Aspirin

Diarmuid Jeffreys traces the story of aspirin from the drug's origins in ancient Egypt, through its industrial development at the end of the nineteenth century and its key role in the great flu pandemic of 1918, to its subsequent exploitation by the pharmaceutical conglomerates and the marvelous powers still being discovered today. Diarmuid Jeffreys is a British writer, journalist, and television producer who has made current affairs and documentary programs for BBC TV, Channel 4, and others. He is also the author of The Bureau: Inside the Modern FBI. He lives with his wife and children in East Sussex. A San Francisco Chronicle Best Book of 2004 "Jeffreys is an extremely clever and accessible writer, and his book is comprehensible while still being smart. If it is possible to get giddy over aspirin, Jeffreys manages it. This enthusiasm injects his well-researched prose with a verve and drama that makes for something of a medical history page-turner."-Oregonian "A remarkable story...This is more than the story of aspirin: It is a history lesson."-San Diego Union-Tribune "Diarmuid Jeffreys seamlessly manages his complicated subject...Throughout, Jeffreys renders an absorbing account of the drug's ride from obscurity to celebrity and around about again to its rebirth as today's wonder drug."-San Francisco Chronicle "One of the most fascinating stories in the whole of medicine."-New Scientist Also available: HC 1-58234-386-1 ISBN 978-158234-386-0 $25.95

Aspirin and the Salicylates focuses principally on aspirin. Topics ranging from analytical chemistry and pediatric medicine, taxonomy and cartels, enzymology and toxicity, to renal functions and rheumatology are also included in this compilation. This book emphasizes that salicylates are polycompetent drugs that influence a large number and variety of biological processes. Their multifactorial actions, in relation to the known therapeutic and toxic effects are clearly described. This text likewise provides a refreshing multidisciplinary approach to aspirins that cover the whole extent from chemical to clinical aspects. This publication is a good reference for clinicians, pharmacists, and students intending to acquire general knowledge of the aspirin and salicylates.

This volume is a state-of-the art resource on the recent advances and clinical management of NSAIDs and aspirin. The text provides a thorough overview of NSAIDS and aspirin, reviewing such topics as pharmacology and mechanisms, clinical effects, and the safety and efficacy of these drugs. It also focuses on the effect of the drugs on the cardiovascular system and in the prevention of GI cancer. Practical recommendations for a safe prescription of NSAIDs are also included. Written by experts in the field, NSAIDs and Aspirin: Recent Advances and Implications for Clinical Management is a comprehensive text of great value to gastroenterologists, rheumatologists, cardiologists, oncologists, orthopedists, trauma and internal medicine specialists.

Navigating the maze of modern American health care is rarely easy; those who enter it are confronted with a dizzying array of specialists, practitioners, and clinics from which to choose, and are forced to make decisions regarding drugs and treatments about which they may know very little. For immigrants, finding their way can be difficult--especially for those to whom Western medicine is itself unfamiliar.In this engaging, accessible, and detail-rich book, Zibin Guo narrates elderly Chinese immigrants' response to contemporary American medicine. Traditional Chinese medicine emphasizes self-care and the medicinal value of foods and herbs; American doctors' responses to the ailments of their Chinese patients can seem impersonal and unnecessarily interventionist. Distrust, expense, and problems of communication and interpretation often frustrate both patient and practitioner.Guo paints a picture of a population that, despite its outward appearance of homogeneity, demonstrates a surprisingly wide variety of health-care knowledge, practice, and belief. Using case materials and interviews, he analyzes the blend of folk treatments and respect for Western science that coexist in the health care regimens of these elderly Chinese immigrants.

From Aspirin to Viagra, insulin to penicillin, and vaccines to vitamin supplements, drugs have become part of our everyday lives. This staggering global industry wasn’t born overnight; advancements in pharmaceutical science have been happening for a long while, over the course of decades and even centuries. This book tells the history of ten prominent substances and how they came to be common household names. It shows how the creation of such influential drugs often began with the right person at the exactly right—or wrong!— time. The chapters tell the stories of geniuses and charlatans; scholars and amateurs; advances won through hard work or pure luck; and ultimately, the handful of resounding successes that revolutionized a global industry. Beyond the pioneers of the most famous drugs in our culture, the book analyzes how our perspective on medical treatment has shifted over the decades. Modern standards for testing and administering substances have created a new set of advantages, setbacks, and stigmas, all of which are discussed herein.

Written by a leading expert on Aspirin-related research, this is the most comprehensive treaty of the history, pharmacological effects and clinical applications of one of the most successful drugs ever. The text is written with a wide audience in mind and to be readily understandable for clinicians, pharmacists, biomedical researchers and pharmacologists alike. This third completely revised edition contains the latest results of clinical and pharmacological research on Acetylsalicylic acid, addressing the multiple pharmacological properties of this famous drug with a balanced view on their translation into clinical practice, including prevention and treatment of cardiovascular diseases, thromboinflammation and colorectal cancer.

Reviewing over a century of aspirin research and use, Aspirin and Related Drugs provides a comprehensive source of information on the history, chemistry, absorption in the body, therapeutic effects, toxicology, elimination, and future uses of aspirin. Highlighting the historical evolution of the salicylates and the commercial development of

Drug-Induced Liver Injury, Volume 85, the newest volume in the Advances in Pharmacology series, presents a variety of chapters from the best authors in the field. Chapters in this new release include Cell death mechanisms in DILI, Mitochondria in DILI, Primary hepatocytes and their cultures for the testing of drug-induced liver injury, MetaHeps an alternate approach to identify IDILI, Autophagy and DILI, Biomarkers and DILI, Regeneration and DILI, Drug-induced liver injury in obesity and nonalcoholic fatty liver disease, Mechanisms of Idiosyncratic Drug-Induced Liver Injury, the Evaluation and Treatment of Acetaminophen Toxicity, and much more. Includes the authority and expertise of leading contributors in pharmacology Presents the latest release in the Advances in Pharmacology series