Autoimmunity COVID 19 Post COVID19 Syndrome and COVID 19 Vaccination

Autoimmunity  COVID 19  Post COVID19 Syndrome and COVID 19 Vaccination
Author: Yehuda Shoenfeld,Arad Dotan
Publsiher: Elsevier
Total Pages: 832
Release: 2022-12-03
Genre: Medical
ISBN: 9780443185670

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Autoimmunity, COVID-19, Post-COVID-19 Syndrome and COVID-19 Vaccination covers all aspects of what is perhaps the most dramatic health crisis in the history of modern medicine. Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) raised major concerns about the association between the virus and various autoimmune manifestations. Over 15 distinct autoantibodies and above 10 different autoimmune diseases were found to develop in COVID-19 patients. Moreover, evidence about recovered COVID-19 patients demonstrates that persistent systemic symptoms, which are believed to have an autoimmune-related mechanism, do exist. As it is of great importance to recognize those autoimmune manifestations of COVID-19 and post-COVID-19 syndrome to properly cope with their outcomes in the ongoing pandemic and the long-term post-pandemic period, this book fulfills a vital need in the medical community. Describe the short and long impact of COVID-19 on autoimmunity Provides understanding to the acute and chronic impact of the SARS-CoV-2 Gives insights into the long-term effects of COVID-19 on recovered patients Provides conclusions on the novel terms "chronic post-COVID-19 syndrome", "post-acute COVID-19 syndrome", and "long COVID-19"

Vaccines and Autoimmunity

Vaccines and Autoimmunity
Author: Yehuda Shoenfeld,Nancy Agmon-Levin,Lucija Tomljenovic
Publsiher: John Wiley & Sons
Total Pages: 394
Release: 2015-07-07
Genre: Science
ISBN: 9781118663431

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In light of the discovery of Autoimmune Syndrome Induced by Adjuvants, or ASIA, Vaccines and Autoimmunity explores the role of adjuvants – specifically aluminum in different vaccines – and how they can induce diverse autoimmune clinical manifestations in genetically prone individuals. Vaccines and Autoimmunity is divided into three sections; the first contextualizes the role of adjuvants in the framework of autoimmunity, covering the mechanism of action of adjuvants, experimental models of adjuvant induced autoimmune diseases, infections as adjuvants, the Gulf War Syndrome, sick-building syndrome (SBS), safe vaccines, toll-like receptors, TLRS in vaccines, pesticides as adjuvants, oil as adjuvant, mercury, aluminum and autoimmunity. The following section reviews literature on vaccines that have induced autoimmune conditions such as MMR and HBV, among others. The final section covers diseases in which vaccines were known to be the solicitor – for instance, systemic lupus erythematosus – and whether it can be induced by vaccines for MMR, HBV, HCV, and others. Edited by leaders in the field, Vaccines and Autoimmunity is an invaluable resource for advanced students and researchers working in pathogenic and epidemiological studies.

The Mosaic of Autoimmunity

The Mosaic of Autoimmunity
Author: Yehuda Shoenfeld,David Isenberg
Publsiher: Elsevier Science Limited
Total Pages: 523
Release: 1989
Genre: Medical
ISBN: 0444811842

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This book comprehensively sets out the common aetiopathogenetic mechanisms shared by many, apparently diverse, diseases of the immune system. Unlike most other texts it does not emphasise the differences between autoimmune diseases, but establishes their many common links including hormonal effects, dietary and immunogenetic influences, complement deficiencies and environmental factors. Special attention is given to the effects of ageing and the relationship with malignancies. The scope of the book is very broad so as to cover the integration of the many diverse components which interact to cause autoimmunity, and it contains many 1988 and 1989 references and over 100 figures and tables, offering an attractive, up-to-date guide to modern concepts. It will greatly assist immunologists wishing to enter the field of autoimmunity, and will serve as an invaluable reference work for those already working in it.

Heaven and Earth

Heaven and Earth
Author: Paolo Giordano
Publsiher: Penguin
Total Pages: 416
Release: 2020-07-21
Genre: Fiction
ISBN: 9781984877321

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A powerful, epic novel of four friends as they grapple with desire, youth, death, and faith in a sweeping story by the international bestselling author of The Solitude of Prime Numbers “Perfect, moving, honest, brilliant, with characters who feel like old friends.” –Andrew Sean Greer, Pulitzer prize-winning author of Less "Heaven and Earth is a stunning achievement and confirms him as an electrifying presence in contemporary fiction.” –André Aciman, author of Call Me By Your Name and Find Me Every summer Teresa follows her father to his childhood home in Puglia, down in the heel of Italy, a land of relentless, shimmering heat, centuries-old olive groves and families who have lived there for generations. She spends long afternoons enveloped in a sunstruck stupor, reading her grandmother's paperbacks. Everything changes the summer she meets the three boys who live on the farm next door: Nicola, Tommaso and Bern - the man Teresa will love for the rest of her life. Raised like brothers on a farm that feels to Teresa almost suspended in time, the three boys share a complex, intimate and seemingly unassailable bond. But no bond is unbreakable and no summer truly endless, as Teresa soon discovers. Because there is resentment underneath the surface of that strange brotherhood, a twisted kind of love that protects a dark secret. And when Bern - the enigmatic, restless gravitational centre of the group - commits a brutal act of revenge, not even a final pilgrimage to the edge of the world will be enough to bring back those perfect, golden hours in the shadow of the olive trees. An unforgettable story of enduring love, the bonds between men, and the all-too-human search for meaning, Heaven and Earth is Paolo Giordano at his best: an author capable of unveiling the depths of the human soul, who has now given us the old-fashioned pleasure of a big, sprawling novel in which to lose ourselves.

Neuro Immune Interactions in Inflammation and Autoimmunity

Neuro Immune Interactions in Inflammation and Autoimmunity
Author: Valentin A. Pavlov,Niccolo Terrando
Publsiher: Frontiers Media SA
Total Pages: 222
Release: 2018-07-24
Genre: Electronic Book
ISBN: 9782889455331

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The nervous system plays an important role in the regulation of immunity and inflammation. On the other hand unbalanced immune responses in inflammatory and autoimmune conditions may have a deleterious impact on neuronal integrity and brain function. Recent studies have characterized neural pathways communicating peripheral inflammatory signals to the CNS, and brain- and spinal cord-derived circuitries controlling various innate and adaptive immune responses and inflammation. A prototypical neural reflex circuit that regulates immunity and inflammation is the vagus nerve-based “inflammatory reflex”. Ongoing research has revealed cellular and molecular mechanisms underlying these neural circuits and indicated new therapeutic approaches in inflammatory and autoimmune disorders. Pharmacological and bioelectronic modulation of neural circuitry has been successfully explored in preclinical settings of sepsis, arthritis, inflammatory bowel disease, obesity-driven disorders, diabetes and other diseases. These studies paved the way to successful clinical trials with bioelectronic neuronal modulation in rheumatoid arthritis and inflammatory bowel disease. Dysregulated release of cytokines and other inflammatory molecules may have a severe impact on brain function. Brain inflammation (neuroinflammation), imbalances in brain neuronal integrity and neurotransmitter systems, and cognitive impairment are characteristic features of post-operative conditions, sepsis, liver diseases, diabetes and other disorders characterized by immune and metabolic dysregulation. Derangements in cytokine release also play a pivotal role in depression. Characteristic brain reactive antibodies in autoimmune conditions, including systemic lupus erythematosus and neuromyelitis optica, significantly contribute to brain pathology and cognitive impairment. These studies, and the simultaneous characterization of neuro-protective cytokines, identified new therapeutic approaches for treating neurological complications in inflammatory and autoimmune disorders. This Frontiers Research Topic is a forum for publishing research findings and methodological and conceptual advances at the intersection of immunology and neuroscience. We hope that presenting new insight into bi-directional neuro-immune communication in inflammation and autoimmunity will foster further collaborations and facilitate the development of new efficient therapeutic strategies.

Mosaic of Autoimmunity

Mosaic of Autoimmunity
Author: Carlo Perricone,Yehuda Shoenfeld
Publsiher: Academic Press
Total Pages: 728
Release: 2019-02-15
Genre: Medical
ISBN: 9780128143070

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The Mosaic of Autoimmunity: The Novel Factors of Autoimmune Diseases describes the multifactorial origin and diversity of expression of autoimmune diseases in humans. The term implies that different combinations of factors in autoimmunity produce varying and unique clinical pictures in a wide spectrum of autoimmune diseases. Most of the factors involved in autoimmunity can be categorized into four groups: genetic, immune defects, hormonal and environmental factors. In this book, the environmental factors are reviewed, including infectious agents, vaccines as triggers of autoimmunity, smoking and its relationship with rheumatoid arthritis, systemic lupus erythematosus, thyroid disease, multiple sclerosis and inflammatory bowel diseases. An entirely new syndrome, the autoimmune/inflammatory syndrome induced by adjuvants (ASIA), is also included, along with other diseases that are now recognized as having an autoimmune etiopathogenesis. Highlights the concept of the mosaic of autoimmune manifestations Includes new visions on unsuspected molecules Provides updated knowledge to physicians helping patients with autoimmune diseases Presents thorough, up-to-date information on specific diseases, along with clinical applications

Feeding During Late Infancy and Early Childhood

Feeding During Late Infancy and Early Childhood
Author: Olle Hernell,Jacques Schmitz
Publsiher: Karger Medical and Scientific Publishers
Total Pages: 253
Release: 2005-01-01
Genre: Health & Fitness
ISBN: 9783805579063

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In its resolution WHA54.2 (2001) the WHO recommends the promotion and support of exclusive breastfeeding for 6 months, and then the provision of safe and appropriate complementary foods whilst continuing breastfeeding until 2 years of age or beyond. The 56 Nutrition Workshop has been specifically developed to review the medical and scientific aspects of these topics and to sustain the Nestle Development Nutrition Program (NDNP).

Podocytopathy

Podocytopathy
Author: Z.-H. Liui,J.C. He
Publsiher: Karger Medical and Scientific Publishers
Total Pages: 277
Release: 2014-05-16
Genre: Medical
ISBN: 9783318026511

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The podocyte is a key cell that forms the last barrier of the kidney filtration unit. One of the most exciting developments in the field of nephrology in the last decade has been the elucidation of its biology and its role in the pathophysiology of inherited and acquired glomerular disease, termed podocytopathy. In this publication, world-renowned experts summarize the most recent findings and advances in the field: they describe the unique biological features and injury mechanisms of the podocyte, novel techniques used in their study, and diagnosis and potential therapeutic approaches to glomerular diseases. Due to its broad scope, this publication is of great value not only for clinical nephrologists and researchers, but also for students, residents, fellows, and postdocs.