Autonomous Robot Aided Optical Manipulation For Biological Cells

Autonomous Robot-Aided Optical Manipulation for Biological Cells gives a systematically and almost self-contained description of the many facets of modeling, sensing, and control techniques or experimentally exploring emerging trends in optical manipulation of biological cell in micro/nanorobotics systems. To achieve biomedical applications, reliability design, modeling, and precision control are vitally important for the development of engineering systems. With the advances in modeling, sensing, and control techniques, it is opportunistic to exploit them for the benefit of reliability design, actuation, and precision control of micro/nanomanipulation systems to expanding the applications of robot at the micro and nano scales, especially in biomedical engineering. This book presents new techniques in reliability modeling and advanced control of robot-aided optical manipulation of biological cells systems. The book will be beneficial to the researchers within robotics, mechatronics, biomedical engineering, and automatic control society, including both academic and industrial parts. Provides a series of latest results in, including but not limited to, design, sensing, actuation, modeling, and control of micro/nano manipulation system using optical tweezers Gives recent advances of theory, technological aspects, and applications of advanced sensing, actuation, modeling and control methodologies in biomedical engineering applications Offers simulation and experimental results in each chapter in order to reflect the biomedical engineering practice, yet demonstrate the main focus of the developed design, analysis and synthesis approaches

Micro/Nano-robotics for Biomedical Applications features a system approach and incorporates modern methodologies in autonomous mobile robots for programmable and controllable micro/nano-robots aiming at biomedical applications. The book provides chapters of instructional materials in micro/nanorobotics for biomedical applications. The book features lecture units on micro/nanorobot components and techniques, including sensors, actuator, power supply, and micro/nano-fabrication and assembly. It also contains case studies on using micro/nano-robots in biomedical environments and in biomedicine, as well as a design example to conceptually develop a Vitamin-pill sized robot to enter human’s gastrointestinal tract. Laboratory modules to teach robot navigation and cooperation methods suitable to biomedical applications will be also provided based on existing simulation and robot platforms.

Robotics for Cell Manipulation and Characterization provides fundamental principles underpinning robotic cell manipulation and characterization, state-of-the-art technical advances in micro/nano robotics, new discoveries of cell biology enabled by robotic systems, and their applications in clinical diagnosis and treatment. This book covers several areas, including robotics, control, computer vision, biomedical engineering and life sciences using understandable figures and tables to enhance readers’ comprehension and pinpoint challenges and opportunities for biological and biomedical research. Focuses on, and comprehensively covers, robotics for cell manipulation and characterization Highlights recent advances in cell biology and disease treatment enabled by robotic cell manipulation and characterization Provides insightful outlooks on future challenges and opportunities

Autonomous Positioning of Piezoactuated Mechanism for Biological Cell Puncture gives a systematic and almost self-contained description of the many facets of advanced design, optimization, modeling, system identification, and advanced control techniques for positioning of the cell puncture mechanism with a piezoelectric actuator in micro/nanorobotics systems. To achieve biomedical applications, reliability design, modeling, and precision control are essential for developing engineering systems. With the advances in mechanical design, dynamic modeling, system identification, and control techniques, it is possible to expand the advancements in reliability design, precision control, and quick actuation of micro/nanomanipulation systems to the robot’s applications at the micro- and nanoscales, especially for biomedical applications. This book unifies existing and emerging techniques concerning advanced design, modeling, and advanced control methodologies in micropuncture of biological cells using piezoelectric actuators with their practical biomedical applications. The book is an essential resource for researchers within robotics, mechatronics, biomedical engineering, and automatic control society, including both academic and industrial parts. KEY FEATURES • Provides a series of latest results in, including but not limited to, design, modeling, and control of micro/nanomanipulation systems utilizing piezoelectric actuators • Gives recent advances of theory, technological aspects, and applications of advanced modeling, control, and actuation methodologies in cell engineering applications • Presents simulation and experimental results to reflect the micro/nano manipulation practice and validate the performances of the developed design, analysis, and synthesis approaches

Robotic engineering inspired by biology—biomimetics—has many potential applications: robot snakes can be used for rescue operations in disasters, snake-like endoscopes can be used in medical diagnosis, and artificial muscles can replace damaged muscles to recover the motor functions of human limbs. Conversely, the application of robotics technology to our understanding of biological systems and behaviors—biorobotic modeling and analysis—provides unique research opportunities: robotic manipulation technology with optical tweezers can be used to study the cell mechanics of human red blood cells, a surface electromyography sensing system can help us identify the relation between muscle forces and hand movements, and mathematical models of brain circuitry may help us understand how the cerebellum achieves movement control. Biologically Inspired Robotics contains cutting-edge material—considerably expanded and with additional analysis—from the 2009 IEEE International Conference on Robotics and Biomimetics (ROBIO). These 16 chapters cover both biomimetics and biorobotic modeling/analysis, taking readers through an exploration of biologically inspired robot design and control, micro/nano bio-robotic systems, biological measurement and actuation, and applications of robotics technology to biological problems. Contributors examine a wide range of topics, including: A method for controlling the motion of a robotic snake The design of a bionic fitness cycle inspired by the jaguar The use of autonomous robotic fish to detect pollution A noninvasive brain-activity scanning method using a hybrid sensor A rehabilitation system for recovering motor function in human hands after injury Human-like robotic eye and head movements in human–machine interactions A state-of-the-art resource for graduate students and researchers.

This book provides an overview of the noteworthy developments in the field of micromachining, with a specific focus on microinjection systems used for biological micromanipulation. The author also explores the design, development, and fabrication of new mechanical designs for micromachines, with plenty of examples that elucidate their modeling and control. The design and fabrication of a piezoelectric microinjector, constant force microinjector, constant force microgripper, PDVF microforce sensor, and a piezoelectric microsyringe are presented as examples of new technology for microinjection systems. This book is appropriate for both researchers and advanced students in bioengineering.