Basic Orthopaedic Biomechanics And Mechano Biology

Biomaterials / Ahmed El-Ghannam and Paul Ducheyne -- Biomechanics of the spine / Ian A. F. Stokes and James C. Iatridis -- Biomechanics of fracture fixation and fracture healing / Lutz E. Claes and Keita Ito -- Biomechanics and preclinical testing of artificial joints: the hip / Rik Huiskes and Jan Stolk -- Biomechanics of total knee replacement designs / Peter S. Walker.

Completely revised and updated, the Third Edition of this classic text reflects the latest advances in research on orthopaedic biomechanics and the successful applications of biomechanical principles in fracture fixation, prosthetic implant design, and hip and knee arthroplasty. For this Third Edition, Dr. Mow is joined by new co-editor Rik Huiskes, PhD, an Editor-in-Chief of the Journal of Biomechanics and an internationally renowned authority in the field. New chapters cover biomaterials, biomechanical principles of cartilage and bone tissue engineering, and biomechanics of fracture fixation and fracture healing.

This classic text has been completely revised and updated to reflect the latest advances in orthopaedic biomechanics, and the successful application of mechanical laws to the locomotor system of the human body. The Second Edition features new chapters on cell-matrix interactions in articular cartilage and on the quantitative anatomy of diarthrodial joints, as well as expanded coverage of the biomechanics of artificial hip and knee joints.

Mechanobiology—the study of the effects of mechanical environments on the biological processes of cells—has evolved from traditional biomechanics via the incorporation of strong elements of molecular and cell biology. Currently, a broad range of organ systems are being studied by surgeons, physicians, basic scientists, and engineers. These mechanobiologists aim to create new therapies and further biological understanding by quantifying the mechanical environment of cells and the molecular mechanisms of mechanically induced pathological conditions. To achieve these goals, investigators must be familiar with both the basic concepts of mechanics and the modern tools of cellular/molecular biology. Unfortunately, current literature contains numerous studies that misuse standard mechanical estimations and terminology, or fail to implement appropriate molecular analyses. Therefore, the Mechanobiology Handbook not only presents cutting-edge research findings across various fields and organ systems, but also provides the elementary chapters on mechanics and molecular analysis techniques to encourage cross-field understanding and appropriate planning. Aided by the continuous advancement of research tools in both mechanics and biology, more sophisticated experiments and analyses are possible—thus fueling the growth of the field of mechanobiology. Considering the complexity of the mechanics and the biology of the human body, most of the world of biomechanics remains to be studied. Since the field is still developing, the Mechanobiology Handbook does not force one unified theory, but brings out many different viewpoints and approaches to stimulate further research questions.

In the latest edition of Benzel’s Spine Surgery, renowned neurosurgery authority Dr. Edward C. Benzel, along with new editor Dr. Michael P. Steinmetz, deliver the most up-to-date information available on every aspect of spine surgery. Improved visuals and over 100 brand-new illustrations enhance your understanding of the text, while 26 new chapters cover today's hot topics in the field. A must-have resource for every neurosurgeon and orthopedic spine surgeon, Benzel's Spine Surgery provides the expert, step-by-step guidance required for successful surgical outcomes. Glean essential, up-to-date information in one comprehensive reference that explores the full spectrum of techniques used in spine surgery. Covers today's hot topics in spine surgery, such as pelvic parameters in planning for lumbar fusion; minimally invasive strategies for the treatment of tumors and trauma of the spine; and biologics and stem cells. A total of 18 intraoperative videos allow you to hone your skills and techniques. New editor Michael P. Steinmetz brings fresh insights and improvements to the text. Features the addition of 26 chapters, including: -Biologics in Spine Fusion Surgery -Endoscopic and Transnasal Approaches to the Craniocervical Junction -Cellular Injection Techniques for Discogenic Pain -Minimally Invasive Techniques for Thoracolumbar Deformity -Spinal Cord Herniation and Spontaneous Cerebrospinal Fluid Leak -MIS Versus Open Spine Surgery Extensive revisions to many of the existing chapters present all of the most up-to-date information available on every aspect of spine surgery. Improved visuals and over 100 brand-new illustrations enhance learning and retention.

This book offers a summary of research on the biomechanics of fracture fixation and mechanobiology of fracture healing. The author, a known expert, provides an overview of the state of art, his own research together with that of his co-workers and collaborators; he describes the ideas and findings from the beginning of this research field in the 1960s up to the clinical consequences and applications of today. The book discusses the mechanobiology of fracture healing, illustrates the numerical methods that simulate fracture healing processes, and depicts specific research methods of experimental studies. Finally, it provides conclusions for the improvement of fracture treatment that will be of use in clinical applications nowadays. This book will be a valuable resource of knowledge for students and scientists in the field of bioengineering, experimental biology, and biomechanics, helping them to identify the correct conditions and analysis for their respective research and receive an understanding of the research field from its beginning until today. For experimental and clinical surgeons active in the field of fracture healing, this book will provide a useful historical overview over this translational research field.

Mechanobiology—the study of the effects of mechanics on biological events—has evolved to answer numerous research questions. Mechanobiology Handbook 2nd Edition is a reference book for engineers, scientists, and clinicians who are interested in mechanobiology and a textbook for senior undergraduate to graduate level students of this growing field. Readers will gain a comprehensive review of recent research findings as well as elementary chapters on solid mechanics, fluid mechanics, and molecular analysis techniques. The new edition presents, in addition to the chapters of the first edition, homework problem sets that are available online and reviews of research in uncovered areas. Moreover, the new edition includes chapters on statistical analysis, design of experiments and optical imaging. The editors of this book are researchers and educators in mechanobiology. They realized a need for a single volume to assist course instructors as a guide for didactic teaching of mechanobiology to a diverse student body. A mechanobiology course is frequently made up of both undergraduate and graduate students pursuing degrees in engineering, biology, or integrated engineering and biology. Their goal was to present both the elementary and cutting-edge aspects of mechanobiology in a manner that is accessible to students from many different academic levels and from various disciplinary backgrounds. Moreover, it is their hope that the readers of Mechanobiology Handbook 2nd Edition will find study questions at the end of each chapter useful for long-term learning and further discussion. Comprehensive collection of reviews of recent research Introductory materials in mechanics, biology, and statistics Discussion of pioneering and emerging mechanobiology concepts Presentation of cutting-edge mechanobiology research findings across various fields and organ systems End of chapter study questions, available online Considering the complexity of the mechanics and the biology of the human body, most of the world of mechanobiology remains to be studied. Since the field is still developing, the Mechanobiology Handbook raises many different viewpoints and approaches with the intention of stimulating further research endeavours.

Human Orthopaedic Biomechanics: Fundamentals, Devices and Applications covers a wide range of biomechanical topics and fields, ranging from theoretical issues, mechanobiology, design of implants, joint biomechanics, regulatory issues and practical applications. The book teaches the fundamentals of physiological loading and constraint conditions at various parts of the musculoskeletal system. It is an ideal resource for teaching and education in courses on orthopedic biomechanics, and for engineering students engaged in these courses. In addition, all bioengineers who have an interest in orthopedic biomechanics will find this title useful as a reference, particularly early career researchers and industry professionals. Finally, any orthopedic surgeons looking to deepen their knowledge of biomechanical aspects will benefit from the accessible writing style in this title. Covers theoretical aspects (mechanics, stress analysis, constitutive laws for the various musculoskeletal tissues and mechanobiology) Presents components of different regulatory aspects, failure analysis, post-marketing and clinical trials Includes state-of-the-art methods used in orthopedic biomechanics and in designing orthopedic implants (experimental methods, finite element and rigid-body models, gait and fluoroscopic analysis, radiological measurements)