Challenges In Delivery Of Therapeutic Genomics And Proteomics

Delivery of therapeutic proteomics and genomics represent an important area of drug delivery research. This text describes the basics of genomics and proteomics and highlights the various chemical, physical and biological approaches to protein and gene delivery.

Delivery of therapeutic proteomics and genomics represent an important area of drug delivery research. Genomics and proteomics approaches could be used to direct drug development processes by unearthing pathways involved in disease pathogenesis where intervention may be most successful. This book describes the basics of genomics and proteomics and highlights the various chemical, physical and biological approaches to protein and gene delivery. Covers a diverse array of topics from basic sciences to therapeutic applications of proteomics and genomics delivery Of interest to researchers in both academia and industry Highlights what’s currently known and where further research is needed

The patenting and licensing of human genetic material and proteins represents an extension of intellectual property (IP) rights to naturally occurring biological material and scientific information, much of it well upstream of drugs and other disease therapies. This report concludes that IP restrictions rarely impose significant burdens on biomedical research, but there are reasons to be apprehensive about their future impact on scientific advances in this area. The report recommends 13 actions that policy-makers, courts, universities, and health and patent officials should take to prevent the increasingly complex web of IP protections from getting in the way of potential breakthroughs in genomic and proteomic research. It endorses the National Institutes of Health guidelines for technology licensing, data sharing, and research material exchanges and says that oversight of compliance should be strengthened. It recommends enactment of a statutory exception from infringement liability for research on a patented invention and raising the bar somewhat to qualify for a patent on upstream research discoveries in biotechnology. With respect to genetic diagnostic tests to detect patient mutations associated with certain diseases, the report urges patent holders to allow others to perform the tests for purposes of verifying the results.

Chitin is the second most abundant biopolymer after cellulose and is a resourceful copious and cheap biomaterial discovered in 1859 owing to significant industrial and technological utility. Raw chitin-chitosan resembles keratin in its biological functions. Chitin chemistry vastly developed via innate unparalleled biological features and exceptional physicochemical characters. Chitosan endures assorted chemical/physical modifications easily at free proactive functionalities, yet intact bulk properties are achieved through processing, viz., film, membrane, composite, hybrid, nanofibre, nanoparticle, hydrogel and scaffolds. Rapidly lessen bioresources signify chitosan as an option due to renewable eco-friendliness and drive embryonic myriad applications in S

This book covers a vast range of information regarding nanotherapeutics, including knowledge based on fundamentals, history and progress, applications, practical aspects and examples, and prospects of nanotherapeutics. It includes the fundamentals of nanotherapeutics, including mechanisms and theories behind the phenomena, summarizing various approaches of nanotherapeutics in the field of medicine. By considering the emerging pandemics and other issues regarding public health, the timely need for novel solutions is also described. Features: Provides a comprehensive knowledge on fundamentals, applications, current situations, and ongoing research in nanotherapeutics. Highlights the practical aspects and prospects to enhance the use of nanotherapeutics in the health field. Illustrates the significance of using nanotherapeutics in futuristic life. Discusses sustainable resolutions to issues in public health. Explores the latest implementations and merits of the fields supported by pertinent examples. This book is aimed at undergraduate, graduate students, and researchers in drug delivery, gene and cancer therapy, biomedical engineering, and nanotechnology.

​This edited book presents all feasible approaches to improve technology of algal biofuels production at both qualitative and quantitative front. The book’s focus in on enhancing mass scale production of algae based biofuels by addressing technological issues and filling the existing gaps to make it smooth for practical as well as commercial implementation. The book also explores in depth analysis of various issues other than technology and related to improve technological significance for practical biofuels production from algae. Low cost strategies and higher mass production is one of the most sounding agenda of the book. The book also evaluates enlighten various sustainable algal biofuels options which are close towards commercial application along with their green future prospect. Societal and environment friendly approach even for commercial application has also been discussed in book. This is a useful reading material for researchers and students of biofuels and reneable energy.

Surface Chemistry of Nanobiomaterials brings together the most recent findings regarding the surface modification of currently used nanomaterials, which is a field that has become increasingly important during the last decade. This book enables the results of current research to reach those who wish to use this knowledge in an applied setting. Leading researchers from around the world present various types of nanobiomaterials, such as quantum dots (QDs), carbon nanotubes, silver nanoparticles, copper oxide, zinc oxide, magnesium oxide, magnetite, hydroxyapatite and graphene, and discuss their related functionalization strategies. This book will be of interest to postdoctoral researchers, professors and students engaged in the fields of materials science, biotechnology and applied chemistry. It will also be highly valuable to those working in industry, including pharmaceutics and biotechnology companies, medical researchers, biomedical engineers and advanced clinicians. An up-to-date and highly structured reference source for researchers, practitioners and students working in biomedical, biotechnological and engineering fields A valuable guide to recent scientific developments, covering major and emerging applications of nanomaterials in the biomedical field Proposes novel opportunities and ideas for developing or improving technologies in nanomedicine and nanobiology

Principles of Biomaterials Encapsulation: Volume One, provides an expansive and in-depth resource covering the key principles, biomaterials, strategies and techniques for encapsulation. Volume One begins with an introduction to encapsulation, with subsequent chapters dedicated to a broad range of encapsulation principles and techniques, including spray chilling and cooling, microemulsion, polymerization, extrusion, cell microencapsulation and much more. This book methodically details each technique, assessing the advantages and disadvantages of each, allowing the reader to make an informed decision when using encapsulation in their research. Principles of Biomaterials Encapsulation: Volume One enables readers to learn about the various strategies and techniques available for encapsulation of a wide selection of biomedical substrates, such as drugs, cells, hormones, growth factors and so on. Written and edited by well-versed materials scientists with extensive clinical, biomedical and regenerative medicine experience, this book offers a deeply interdisciplinary look at encapsulation in translational medicine. As such, this book will provide a useful resource to a broad readership, including those working in the fields of materials science, biomedical engineering, regenerative and translational medicine, pharmacology, chemical engineering and nutritional science. Details the various biomaterials available for encapsulation, as well as advantages and disadvantages of conventional and contemporary biomaterials for encapsulations Describes a broad range of applications in regenerative medicine, uniquely bringing encapsulation into the worlds of translational medicine and tissue engineering Written and edited by well-versed materials scientists with extensive clinical, biomedical and regenerative medicine experience, offering an interdisciplinary approach