Cindy And Cristabelles Big Scare

Cindy and Cristabelle are two little fainting goats with big worries. After all, while life at Lil Steps Farm seems happy and safe, it could change at any moment! Yet no matter how cautious they are, their worries and fears keep growing, and soon Cindy and Cristabelle don’t know where to turn. Lucky for them, they have a friend in Percy the Pig. He’ll teach the goats that when you take a moment to appreciate the world around you, you’ll realize there’s a lot of reasons to feel as happy as happy can be! Cindy and Cristabelle’s Big Scare tackles the subject of childhood anxiety disorders in two stages: the storybook and the workbook. This approach helps adults to learn more about anxiety and how to manage it together with their child. Adults and children alike will love joining the animals of Lil Steps Farm in learning more about worries and fears, and how to overcome them!

Cindy and Cristabelle are two little fainting goats with big worries. After all, while life at Lil' Steps Farm seems happy and safe, it could change at any moment! Yet no matter how cautious they are, their worries and fears keep growing, and soon Cindy and Cristabelle don’t know where to turn. Lucky for them, they have a friend in Wilbert the Pig. He’ll teach the goats that when you take a moment to appreciate the world around you, you’ll realize there’s a lot of reasons to feel as happy as happy can be! Cindy and Cristabelle’s Big Scare tackles the subject of childhood anxiety disorders in two stages: the storybook and the workbook. This approach helps adults to learn more about anxiety and how to manage it together with their child. Adults and children alike will love joining the animals of Lil' Steps Farm in learning more about worries and fears, and how to overcome them!

With an emphasis on simple preparation and fresh foods, the author offers seasonal recipes for Forth of July picnics, Valentine's Day treats, and warming winter meals.

PARP Inhibitors for Cancer Therapy provides a comprehensive overview of the role of PARP in cancer therapy. The volume covers the history of the discovery of PARP (poly ADP ribose polymerase) and its role in DNA repair. In addition, a description of discovery of the PARP family, and other DNA maintenance-associated PARPs will also be discussed. The volume also features a section on accessible chemistry behind the development of inhibitors. PARP inhibitors are a group of pharmacological inhibitors that are a particularly good target for cancer therapy. PARP plays a pivotal role in DNA repair and may contribute to the therapeutic resistance to DNA damaging agents used to treat cancer. Researchers have learned a tremendous amount about the biology of PARP and how tumour-specific defects in DNA repair can be exploited by PARPi. The “synthetic lethality” of PARPi is an exciting concept for cancer therapy and has led to a heightened activity in this area.

Ellen Franck isn't in love with Big Bird. After all, he's a big yellow Sesame Street character -- and she's an intelligent single woman with a fabulous job. On the other hand, Big Bird is looking like a better candidate for fatherhood every day: he's tall, affectionate, and steadily employed. And right now, for Ellen, thirty-five years old and dying to have a baby, almost any father will do. In her hilarious and heartbreaking new novel, Laura Zigman, bestselling author of Animal Husbandry, explores what happens when the life we've chosen isn't that life we expected it to be. And at this point Ellen Franck is rethinking all her choices. Mired in a relationship with a man who is better at brooding than breeding, sister to a woman who can't seem to stop having babies, and working under a boss who is about to have the baby shower of the decade, Ellen knows the path to motherhood is clear. All she has to do is leave her relationship, horrify her family, find an anonymous father, and become independently wealthy. Piece of cake.

Secrets have consequences. If given the power, they will lead you into a life you never dreamed of or wanted. Brooke Lake is a girl caught in a town and a life she yearns to escape. Full of anger, fear, and questions without answers, she runs from her problems only to lose herself in a world that’s too much for her. Molly Shirley is a woman without a past and no foreseeable future. Her body is her best commodity, so she does whatever she has to do to survive. Broken by lies, Brooke and Molly must explore the parts of themselves they would rather keep secret. Only by confronting the past can they develop the strength to create a life of their own making—a life where love and forgiveness never come too late. An intriguing drama that both repels and magnetizes the reader to the page, Beneath the Silence follows the story of a woman's struggle to make sense of a dark world. Explore the hold of the past in this gripping novel and witness the strength it takes to break free from pain and create a life worth living.