Electromagnetism Quanta And Electron Flow In The Electrophysiology Of Living Cells
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Electromagnetism Quanta And Electron Flow In The Electrophysiology Of Living Cells
Author | : Mark Noble |
Publsiher | : World Scientific |
Total Pages | : 220 |
Release | : 2021-08-24 |
Genre | : Science |
ISBN | : 9789811234965 |
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Electrons are involved in all electrical phenomena, and living cells cannot be an exception. This book takes on a decidedly different approach to existing texts on electrophysiology, by considering electrical physiological processes from the viewpoint of electron flow, rather than the conventional notion of ion movement. It concisely describes the theoretical background of electron density and cellular voltage, before exploring thought-provoking questions such as the relationship between electrolyte distribution and transmembrane potential, and the source of electricity generation in living cells. A new electromagnetic theory of muscular function is presented, and all topics of relevance — including the electrophysiology of invertebrates, plants, fungi and bacteria — are comprehensively covered. Using plain language and more than 40 original illustrations, the author has designed each chapter to provide a succinct overview of an individual topic in a format that appeals to both the expert and the uninitiated. Electromagnetism, Quanta, and Electron Flow in the Electrophysiology of Living Cells proffers a refreshingly new way to understand a fascinatingly old subject.
Electromagnetism Quanta And Electron Flow In The Electrophysiology Of Living Cells
Author | : Mark I. M. Noble |
Publsiher | : Unknown |
Total Pages | : 220 |
Release | : 2021 |
Genre | : Electromagnetism |
ISBN | : 9811234957 |
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"This book differs from existing texts on electrophysiology by considering electrical physiological processes from the viewpoint of electron flow, rather than the conventional notion of ion movement. The content is comprehensive, covering the electrophysiology of organs and glands in vertebrates, as well as invertebrates, plants, fungi and bacteria"--
Conversations on Cardiac Physiology
Author | : Mark Noble |
Publsiher | : Cambridge Scholars Publishing |
Total Pages | : 175 |
Release | : 2023-12-08 |
Genre | : Medical |
ISBN | : 9781527556416 |
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This book addresses and corrects widespread misconceptions regarding heart physiology. Such misconceptions include: the voltage in cells is attributed to potassium ion concentration differences between the extracellular and intracellular compartments, which are the same in all organs of the body, whereas the voltage in cells of these same organs vary widely. This book argues that depolarisation and repolarisation can be explained by electron outflow and mitochondrial production, respectively; and that the trigger for internal calcium ion release is calcium ions bound to the inner leaflet of the cell membrane. In the book, Starling’s Law is contrasted with contractility increase, and it is posited that hypertension is not caused by salty diet, coronary artery disease risk is not correlated with total cholesterol (rather, only with some specific cholesterols), and that drug administration should be titrated.
Starling s Law of The Heart Revisited
Author | : Henk Keurs,M.I.M Noble |
Publsiher | : Springer Science & Business Media |
Total Pages | : 157 |
Release | : 2012-12-06 |
Genre | : Medical |
ISBN | : 9789400913134 |
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H. E. D. J. TER KEURS & M. I. M. NOBLE The "Starling's Law of the Heart" and "The Frank-Starling Mechanism" have long been the cornerstone of cardiac mechanical physiology. It is often forgotten that Frank and Starling carried out fundamentally different exper iments. Frankl measured the isovolumic pressure developed by frog heart at different volumes. He therefore discovered the pressure-volume-volume rela tionship which depends directly on the force-length relationship of the 2 sarcomeres. Starling ,3 studied cardiac shortening as manifest by cardiac output and its relationship to end-diastolic conditions as manifest by right atrial pressure. Thus he was studying the ability of cardiac muscle to shorten more at a given load from a greater initial length. Starling in the promulga 4 tions of his law implied a common mechanism for these two phenomena and spoke of the "energy liberated" being a function of initial muscle fiber length. However, there has been much confusion about the interrelationship between the two different aspects studied by Frank and Starling. The 1960s saw the era of isolated cardiac muscle mechanics, beginning with 5 the paper of Abbott and Mommaerts. Whole muscle length-tension relations were equated with sarcomere-length-tension relations by fixation of muscle at a particular point on the curve and determination of sarcomere length by electronmicroscopy.
Integrative Biophysics
Author | : Fritz-Albert Popp,L.V. Beloussov |
Publsiher | : Springer Science & Business Media |
Total Pages | : 499 |
Release | : 2013-03-09 |
Genre | : Science |
ISBN | : 9789401703734 |
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Most of the specialists working in this interdisciplinary field of physics, biology, biophysics and medicine are associated with "The International Institute of Biophysics" (IIB), in Neuss, Germany, where basic research and possibilities for applications are coordinated. The growth in this field is indicated by the increase in financial support, interest from the scientific community and frequency of publications. Audience: The scientists of IIB have presented the most essential background and applications of biophotonics in these lecture notes in biophysics, based on the summer school lectures by this group. This book is devoted to questions of elementary biophysics, as well as current developments and applications. It will be of interest to graduate and postgraduate students, life scientists, and the responsible officials of industries and governments looking for non-invasive methods of investigating biological tissues.
Medical Physics and Biomedical Engineering
Author | : B.H Brown,R.H Smallwood,D.C. Barber,P.V Lawford,D.R Hose |
Publsiher | : Taylor & Francis |
Total Pages | : 768 |
Release | : 2017-09-06 |
Genre | : Medical |
ISBN | : 9781439833735 |
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Medical Physics and Biomedical Engineering provides broad coverage appropriate for senior undergraduates and graduates in medical physics and biomedical engineering. Divided into two parts, the first part presents the underlying physics, electronics, anatomy, and physiology and the second part addresses practical applications. The structured approach means that later chapters build and broaden the material introduced in the opening chapters; for example, students can read chapters covering the introductory science of an area and then study the practical application of the topic. Coverage includes biomechanics; ionizing and nonionizing radiation and measurements; image formation techniques, processing, and analysis; safety issues; biomedical devices; mathematical and statistical techniques; physiological signals and responses; and respiratory and cardiovascular function and measurement. Where necessary, the authors provide references to the mathematical background and keep detailed derivations to a minimum. They give comprehensive references to junior undergraduate texts in physics, electronics, and life sciences in the bibliographies at the end of each chapter.
Introduction to Electrophysiological Methods and Instrumentation
Author | : Franklin Bretschneider,Jan R. de Weille |
Publsiher | : Academic Press |
Total Pages | : 370 |
Release | : 2018-11-13 |
Genre | : Science |
ISBN | : 9780128142110 |
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Introduction to Electrophysiological Methods and Instrumentation, Second Edition covers all topics of interest to electrophysiologists, neuroscientists and neurophysiologists, from the reliable penetration of cells and the behavior and function of the equipment, to the mathematical tools available for analyzing data. It discusses the pros and cons of techniques and methods used in electrophysiology and how to avoid pitfalls. Although the basics of electrophysiological techniques remain the principal purpose of this second edition, it now integrates several current developments, including, amongst others, automated recording for high throughput screening and multimodal recordings to correlate electrical activity with other physiological parameters collected by optical means. This book provides the electrophysiologist with the tools needed to understand his or her equipment and how to acquire and analyze low-voltage biological signals. Introduces possibilities and solutions, along with the problems, pitfalls, and artefacts of equipment and electrodes Discusses the particulars of recording from brain tissue slices, oocytes and planar bilayers Describes optical methods pertinent to electrophysiological practice Presents the fundamentals of signal processing of analogue signals, spike trains and single channel recordings, along with procedures for signal recording and processing Includes appendices on electrical safety and foundations of useful mathematical tools
Nonlinear Electrodynamics in Biological Systems
Author | : W. Adey |
Publsiher | : Springer Science & Business Media |
Total Pages | : 589 |
Release | : 2012-12-06 |
Genre | : Science |
ISBN | : 9781461327899 |
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The past half century has seen an extraordinary growth in the fields of cellular and molecular biology. From simple morphologi cal concepts of cells as the essential units of living matter there has been an ever-sharper focus on functional organization of living systems, with emphasis on molecular dynamics. Thus, life forms have come to be defined increasingly in terms of metabolism, growth, reproduction and responses to environmental perturbations. Since these properties occur in varying degrees in systems below the level of cellular organization, there has been a blurring of older models that restricted the concepts of life to cellular systems. At the same time, a search has begun for elemental as pects of molecular and atomic behavior that might better define properties common to all life forms. This search has led to an examination of nonlinear behavior in biological macromolecules, whether in response to electrical or chemical stimulation, for example, or as a means of signaling along a molecular chain, or as a means of energy transfer. Experimental knowledge in this area has grown rapidly in the past decade, and in some respects has outstripped theoretical models adequate to ex plain these new observations. Nevertheless, it can be claimed that there is now an impressive body of experiments implicating non linear, nonequilibrium processes as fundamental steps in sequential operations of biological systems.