Human Embryos And Preimplantation Genetic Technologies
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Human Embryos and Preimplantation Genetic Technologies
Author | : E. Scott Sills,Gianpiero D. Palermo |
Publsiher | : Academic Press |
Total Pages | : 224 |
Release | : 2019-05-01 |
Genre | : Science |
ISBN | : 9780128167441 |
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Human Embryos and Preimplantation Genetic Technologies: Ethical, Social, and Public Policy Aspects presents the first holistic analysis of PGD and PGS as it is practiced and regulated worldwide. In addition to scientific and technical aspects, the book provides perspectives on the ethical, legal, religious, policy and social implications of global assisted reproduction technologies, including in Africa, Asia, Europe, North and South America, and Australia. Chapters cover history, ethics, feminism, family dynamics, psychological and interpersonal factors, the current state of PGD and PGS in 20 different sovereign nations and religious communities, and provide an analysis of public policy concerns and future directions. - Provides an in-depth discussion of PGD and PGS as practiced and regulated worldwide - Offers an accessible resource for researchers, medical professionals, patients, regulators and policymakers seeking expert opinions on PGS and PGD - Contains chapters contributed by international clinicians, researchers and thought leaders in the field of assisted reproductive technology
EmbryoGenetics
Author | : Carlos Simón,Carmen Rubio |
Publsiher | : Unknown |
Total Pages | : 176 |
Release | : 2021 |
Genre | : Electronic Book |
ISBN | : 3036511539 |
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The science of human gene ...
Preimplantation Genetic Testing
Author | : Darren K. Griffin,Gary L. Harton |
Publsiher | : CRC Press |
Total Pages | : 208 |
Release | : 2020-06-01 |
Genre | : Medical |
ISBN | : 9780429820304 |
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Preimplantation genetic testing (PGT) is now well established as a valuable treatment option for patients wishing to start or continue a family, for a range of indications from advanced maternal age to high risk of transmitting inherited disease. This text brings together contemporary thinking from international opinion leaders and will be an invaluable guide for practitioners in Reproductive Medicine wishing to keep pace with the latest developments and clinical data.
Comparative Legal Frameworks for Pre Implantation Embryonic Genetic Interventions
Author | : Pin Lean Lau |
Publsiher | : Springer |
Total Pages | : 326 |
Release | : 2019-08-01 |
Genre | : Law |
ISBN | : 9783030223083 |
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This book discusses the possibilities for the use of international human rights law (and specifically, international biomedical laws related to the protection of human rights and the human genome) to provide a guiding framework for the future regulation of genetic modifications applied to human embryos and other precursor materials, when these are made with the aim of implanting a genetically altered embryo in a woman. The significance and timeliness of the work derives from the recent availability of CRISPR/Cas9 and other gene editing tools, and from lacunae in international law regarding the legality of embryo modification with these tools and appropriate governance structures for the oversight of resulting practices. The emergence of improved genome editing tools like CRISPR/Cas9, holds the promise of eradicating genetic diseases in the near future. But its possible future applications with Pre-Implantation Genetic Diagnosis (PGD) raises a plethora of legal and ethical concerns about "remaking" future human beings. The work aims to address an urgent call, to embed these rising concerns about biomedical advancements into the fundamental tailoring of legal systems. Suitable regulatory approaches, coupled with careful reflection of global biomedical laws and individual constitutional systems must be explored. The Book analyzes the impact of reproductive biomedical technologies on the legal and ethical dimensions of regulatory frameworks in selected constitutional systems like the US, the UK, Australia, Malaysia and Thailand. Employing a comparative law methodology, the work reveals a dynamic intersection between legal cultures, socio-philosophical reasoning and the development of a human rights-based framework in bio-political studies. Navigating towards a truly internationalized biomedical approach to emerging technologies, it presents an understanding why a renegotiation and reinvigoration of a contemporary and "new" universal shared values system in the international human rights discourse is now necessary.
PGD and Embryo Selection
Author | : Ingileif Jónsdóttir |
Publsiher | : Nordic Council of Ministers |
Total Pages | : 158 |
Release | : 2005 |
Genre | : Medical |
ISBN | : 9789289312592 |
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Human Gametes and Preimplantation Embryos
Author | : David K. Gardner,Denny Sakkas,Emre Seli,Dagan Wells |
Publsiher | : Springer Science & Business Media |
Total Pages | : 307 |
Release | : 2013-05-27 |
Genre | : Health & Fitness |
ISBN | : 9781461466512 |
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In recent years, the advancing science and increasing availability of assisted reproduction have given new hope to infertile couples. However, the use of IVF and ART has also led to marked increases in the number of multiple-infant live births. This poses a public health concern, as these neonates have a higher rate of pre-term delivery, compromising their survival chances and increasing their risk of lifelong disability. By optimizing the selection of gametes and embryos with high probabilities of implantation, it is possible to reduce the number of embryos transferred and, by extension, the number of high-risk multiple gestations, while maintaining or increasing pregnancy rates. Human Gametes and Preimplantation Embryos: Assessment and Diagnosis provides a broad yet concise overview of established and developing methodologies for assessment of gamete and embryo viability in assisted reproduction. This book elucidates the best practices for precisely selecting viable specimens based on morphology and cleavage rate and covers the spectrum of emerging adjunctive technologies for predicting reproductive potential. The authors present their extensive knowledge of “omics” approaches (genomics, transcriptomics, proteomics, and metabolomics), with unbiased delineation of the associated advantages and potential pitfalls. This valuable clinical resource is well suited to infertility specialists, Ob/Gyn physicians, IVF laboratory technicians, and researchers in the fields of embryology and reproductive medicine.
Redesigning Humans
Author | : Gregory Stock |
Publsiher | : Houghton Mifflin Harcourt |
Total Pages | : 300 |
Release | : 2003 |
Genre | : Medical |
ISBN | : 0618340831 |
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Writing for the lay reader, Stock, the director of the Program on Medicine, Technology, and Society at the School of Public Health at UCLA, discusses the science, potential impact, and many controversies surrounding the development of germline engineering, which involves selectively altering human g
Heritable Human Genome Editing
Author | : The Royal Society,National Academy of Sciences,National Academy of Medicine,International Commission on the Clinical Use of Human Germline Genome Editing |
Publsiher | : National Academies Press |
Total Pages | : 239 |
Release | : 2021-01-16 |
Genre | : Medical |
ISBN | : 9780309671132 |
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Heritable human genome editing - making changes to the genetic material of eggs, sperm, or any cells that lead to their development, including the cells of early embryos, and establishing a pregnancy - raises not only scientific and medical considerations but also a host of ethical, moral, and societal issues. Human embryos whose genomes have been edited should not be used to create a pregnancy until it is established that precise genomic changes can be made reliably and without introducing undesired changes - criteria that have not yet been met, says Heritable Human Genome Editing. From an international commission of the U.S. National Academy of Medicine, U.S. National Academy of Sciences, and the U.K.'s Royal Society, the report considers potential benefits, harms, and uncertainties associated with genome editing technologies and defines a translational pathway from rigorous preclinical research to initial clinical uses, should a country decide to permit such uses. The report specifies stringent preclinical and clinical requirements for establishing safety and efficacy, and for undertaking long-term monitoring of outcomes. Extensive national and international dialogue is needed before any country decides whether to permit clinical use of this technology, according to the report, which identifies essential elements of national and international scientific governance and oversight.