In Vitro Fertilization

This fully updated new edition of a successful and popular practical guide is an indispensable account of modern in-vitro fertilization practice. Initial chapters cover theoretical aspects of gametogenesis and embryo development at the cellular and molecular level, while the latter half of the book describes the requisites for a successful IVF laboratory and the basic technologies in ART. Advanced techniques, including pre-implantation genetic diagnosis, vitrification and stem-cell technology, are comprehensively covered, providing up-to-date analyses of these groundbreaking technologies. This edition includes: • New practical techniques, including preservation of fertility for cancer patients, stem-cell biology/technology, vitrification and in-vitro maturation • A 'refresher' study review of fundamental principles of cell and molecular biology • The latest information available from animal and human research in reproductive biology Packed with a wealth of practical and scientific detail, this is a must for all IVF practitioners.

This book provides updates on the most recent developments in individualized infertility treatment resulting in improved outcomes.

Now in its revised and expanded second edition - including over 20 new chapters - this comprehensive textbook remains a unique and accessible description of the current and developing diagnostic and treatment techniques and technologies comprising in vitro fertilization (IVF). Arranged thematically in sections, each chapter covers a key topic in IVF in a sensible presentation. Parts one and two describe the planning, design and organization of an ART unit and IVF laboratory and equipment and systems, respectively. The sections that follow provide detailed descriptions of IVF techniques, embryo culture methods, sperm processing and selection, insemination procedures, micromanipulation, embryo evaluation, cryopreservation, and embryo transfer. Concluding sections address issues of management and regulation of ART labs across the globe, as well as special topics and emerging techniques and devices. Chapter authors, all experts in the field, contribute their expertise from around the world. With the addition of learning key points and review questions at the beginning and end of each chapter, this new edition of In Vitro Fertilization is a readily accessible, high quality instructional resource for reproductive medicine trainees at all levels. Practicing reproductive endocrinologists, urologists, and embryologists also will find value in the book, as will infertility researchers.

A comprehensive guide for trainee embryologists and medical students in the specialized techniques and technology of assisted reproduction.

Cover -- Half Title -- Title Page -- Copyright Page -- Dedication -- Contents -- Preface -- Contributors -- 1. IVF: The First Four Decades -- 2. Evaluation and Preparation of the Infertile Couple for In Vitro Fertilization -- 3. Carrier Screening -- 4. Testing Ovarian Reserve -- 5. Basics of Ovarian Stimulation -- 6. Role of Antagonists in Human IVF: The Tool for a Safer and More Patient Friendly IVF -- 7. Ultrasonography in IVF -- 8. Oocyte Retrieval -- 9. In Vitro Maturation for Clinical Use -- 10. Sperm Preparation for IVF and ICSI -- 11. Assisted Fertilization -- 12. Analysis of Fertilization -- 13. Human Embryo Development and Assessment of Viability -- 14. Embryo Culture Systems -- 15. Polar Body, Cleavage Stage and Trophectoderm Biopsy -- 16. Pre-implantation Genetic Testing -- 17. Oocytes and Embryo Cryopreservation -- 18. Quality Control and Quality Assurance in the IVF Laboratory -- 19. Oocyte Donation -- 20. Endometrial Receptivity -- 21. Embryo Transfer -- 22. Multiple vs. Singleton Births: Consequences and Prevention -- 23. Monitoring and Evaluation of Infertility Treatments: Is There a Priority for Monitoring of Cognitive Function in Children Born from ART and Other Treatments? -- Index

Offers a comprehensive guide to assisted reproductive technology surveillance, describing its history, global variations, and best practices.

This book discusses the common principles of morality and ethics derived from divinely endowed intuitive reason through the creation of al-fitr' a (nature) and human intellect (al-‘aql). Biomedical topics are presented and ethical issues related to topics such as genetic testing, assisted reproduction and organ transplantation are discussed. Whereas these natural sources are God’s special gifts to human beings, God’s revelation as given to the prophets is the supernatural source of divine guidance through which human communities have been guided at all times through history. The second part of the book concentrates on the objectives of Islamic religious practice – the maqa' sid – which include: Preservation of Faith, Preservation of Life, Preservation of Mind (intellect and reason), Preservation of Progeny (al-nasl) and Preservation of Property. Lastly, the third part of the book discusses selected topical issues, including abortion, assisted reproduction devices, genetics, organ transplantation, brain death and end-of-life aspects. For each topic, the current medical evidence is followed by a detailed discussion of the ethical issues involved.

Say "biological clock" and most people think "women." Yet men have biological clocks too, reveals Dr. Harry Fisch, one of the country's leading experts in male infertility and author of this groundbreaking new book, The Male Biological Clock. Men's clocks tick at a different rate from women's and of course cause an entirely different set of bodily and behavioral changes over the course of a lifetime. But while men's clocks don't strike a "midnight" toll heralding an end to fertility the way menopause does for women, male fertility, testosterone levels, and sexuality all do decline with age. Dr. Fisch's book emphasizes that even young men can have testosterone levels as low as those of much older men, leading to infertility, sexual problems, and other serious health issues. Another startling revelation is that men over thirty-five are twice as likely to be infertile as men younger than twenty-five. In addition, as men age, the quality of their sperm declines significantly, giving rise to an increased chance of a Down syndrome baby, other genetic abnormalities, and miscarriage. Every couple should know all the risks and issues facing men, because these affect two of the most important things in their life: their ability to have children and their capacity to have good sex. The Male Biological Clock is must reading for every man and every couple who is struggling to have children or improve their sex life. Many of Dr. Harry Fisch's findings are startling -- beginning with the fact that infertility is not mostly a women's problem -- and he offers many helpful suggestions for how to deal with declining testosterone, changing sexual needs, and the fertility industry. We have all heard stories of men becoming fathers in their seventies or even eighties, yet most of us are unaware that these are dangerously deceptive exceptions. Older men face a number of increased risks as fathers, and often find their sex lives and well-being changing considerably. The good news: Much can be done to slow down and even reverse the effects of a man's biological clock. The Male Biological Clock tells you what you need to know and how you can achieve optimal fertility and sexuality.