Life As We Made It

From the first dog to the first beefalo, from farming to CRISPR, the human history of remaking nature When the 2020 Nobel Prize was awarded to the inventors of CRISPR, the revolutionary gene-editing tool, it underlined our amazing and apparently novel powers to alter nature. But as biologist Beth Shapiro argues in Life as We Made It, this phenomenon isn’t new. Humans have been reshaping the world around us for ages, from early dogs to modern bacteria modified to pump out insulin. Indeed, she claims, reshaping nature—resetting the course of evolution, ours and others’—is the essence of what our species does. In exploring our evolutionary and cultural history, Shapiro finds a course for the future. If we have always been changing nature to help us survive and thrive, then we need to avoid naive arguments about how we might destroy it with our meddling, and instead ask how we can meddle better. Brilliant and insightful, Life as We Made It is an essential book for the decades to come.

I guess I always felt even if the world came to an end, McDonald's still would be open. High school sophomore Miranda's disbelief turns to fear in a split second when an asteroid knocks the moon closer to Earth, like "one marble hits another." The result is catastrophic. How can her family prepare for the future when worldwide tsunamis are wiping out the coasts, earthquakes are rocking the continents, and volcanic ash is blocking out the sun? As August turns dark and wintery in northeastern Pennsylvania, Miranda, her two brothers, and their mother retreat to the unexpected safe haven of their sunroom, where they subsist on stockpiled food and limited water in the warmth of a wood-burning stove. Told in a year's worth of journal entries, this heart-pounding story chronicles Miranda's struggle to hold on to the most important resource of all--hope--in an increasingly desperate and unfamiliar world. An extraordinary series debut Susan Beth Pfeffer has written several companion novels to Life As We Knew It, including The Dead and the Gone, This World We Live In, and The Shade of the Moon.

In the final years of the twentieth century, emigres from mechanical and electrical engineering and computer science resolved that if the aim of biology was to understand life, then making life would yield better theories than experimentation. Sophia Roosth, a cultural anthropologist, takes us into the world of these self-named synthetic biologists who, she shows, advocate not experiment but manufacture, not reduction but construction, not analysis but synthesis. Roosth reveals how synthetic biologists make new living things in order to understand better how life works. What we see through her careful questioning is that the biological features, theories, and limits they fasten upon are determined circularly by their own experimental tactics. This is a story of broad interest, because the active, interested making of the synthetic biologists is endemic to the sciences of our time."

Someday I often wonder what does it mean when we say someday. Is it now? Is it tomorrow? I am still waiting for the meaning. I ask you, why do I have to wait for someday? Life is short! I know it well, we need to stop putting off, pray tell. We need to grasp all our energy today. We never know when our day will come. So I urge you so plain, grab that moment and run . . . Readers Review Dear Ruthie, Thank you for sharing - Your book has touched my heart. I appreciate it. It gave me more strength to be "me" and It is okay to be me. It taught me a lession. "All I can do is to do my best and go on. . . " Sincerely Your Friend June Register Nurse, TN

· What’s happening in the world lately? · How can I be happy when so many are not? · Is life about following your heart or taking what’s served to you? · Who were the prophets, what areangels, and what happens when we die? · What happened to our ancient civilizations, do secret societies have any real secrets, and are aliens now visiting us? · What’s real? What matters? Who says? Who cares? · How do we know or find our purpose? Many of us ask ourselves these questions, and many more, as we go through our days and try to make sense of our lives. Mike Dooley asks them too, except . . . his questions get answered. Wisely. Compassionately. Fully. One such answer explained its source, stating that we all have a higher self within that predates this life and will live beyond it, and thus it knows a whole lot more than we do about where we’ve been, why we’re here, and what will likely happen next on planet Earth. Life on Earth takes the form of a journal in which Mike asks what’s on his mind during pivotal times in his life. As one of today’s most respected New Thought leaders and reality theorists, he offers a lofty platform for this wide-ranging dialogue that powerfully expands our perspectives on essential truths, taking on topics such as: · Why and how to see through the “illusions” of life on earth · How to make sense of natural disasters and man-made tragedies · Living deliberately, creating consciously, and finding your power · Wealth, relationships, “past lives,” and the evolution of consciousness · The ultimate reason for life on earth (it’s shockingly simple) These are questions asked from the heart with a cautious, even suspicious, mind. Mike explores the subtleties of the replies in depth and detail using his trademark wit and realism, in this intrepid explorer’s guide to the jungles of time and space.

NEW YORK TIMES BESTSELLER • A stunning “portrait of the enduring grace of friendship” (NPR) about the families we are born into, and those that we make for ourselves. A masterful depiction of love in the twenty-first century. NATIONAL BOOK AWARD FINALIST • MAN BOOKER PRIZE FINALIST • WINNER OF THE KIRKUS PRIZE A Little Life follows four college classmates—broke, adrift, and buoyed only by their friendship and ambition—as they move to New York in search of fame and fortune. While their relationships, which are tinged by addiction, success, and pride, deepen over the decades, the men are held together by their devotion to the brilliant, enigmatic Jude, a man scarred by an unspeakable childhood trauma. A hymn to brotherly bonds and a masterful depiction of love in the twenty-first century, Hanya Yanagihara’s stunning novel is about the families we are born into, and those that we make for ourselves. Look for Hanya Yanagihara’s latest bestselling novel, To Paradise.

After being diagnosed with terminal cancer, a professor shares the lessons he's learned—about living in the present, building a legacy, and taking full advantage of the time you have—in this life-changing classic. "We cannot change the cards we are dealt, just how we play the hand." —Randy Pausch A lot of professors give talks titled "The Last Lecture." Professors are asked to consider their demise and to ruminate on what matters most to them. And while they speak, audiences can't help but mull over the same question: What wisdom would we impart to the world if we knew it was our last chance? If we had to vanish tomorrow, what would we want as our legacy? When Randy Pausch, a computer science professor at Carnegie Mellon, was asked to give such a lecture, he didn't have to imagine it as his last, since he had recently been diagnosed with terminal cancer. But the lecture he gave—"Really Achieving Your Childhood Dreams"—wasn't about dying. It was about the importance of overcoming obstacles, of enabling the dreams of others, of seizing every moment (because "time is all you have . . . and you may find one day that you have less than you think"). It was a summation of everything Randy had come to believe. It was about living. In this book, Randy Pausch has combined the humor, inspiration and intelligence that made his lecture such a phenomenon and given it an indelible form. It is a book that will be shared for generations to come.

What do biologists want? How will we know when we have 'made sense' of life? Explanations in the biological sciences are provisional and partial, judged by criteria as heterogenous as their subject matter. This text accounts for this diversity.