Lipoprotein Protocols

Lipoprotein Protocols
Author: Jose M. Ordovas
Publsiher: Unknown
Total Pages: 284
Release: 1998
Genre: Medical
ISBN: 1592595820

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In Lipoprotein Protocols, Jose Ordovas compiles a cutting-edge collection of molecular protein techniques for studying advanced aspects of lipoprotein structure and metabolism. These step-by-step methods allow both the beginning and the advanced researcher to carry out not only fundamental, but also the most advanced genetic screening techniques, including RT-PCR and the preparation of relevant models of transgenic and knockout mice. In addition, novel techniques are presented to characterize plasma lipoproteins, their subfractions, and their modifications, and to determine the activity of relevant enzymes and carrier proteins. Each method is described in easily reproducible detail by hands-on experts who have perfected it. Lipoprotein Protocols offers many powerful tools for unraveling the complexity of lipoprotein metabolism and determining the individual risk of coronary heart disease. For all those basic and clinical investigators seeking to advance the frontier of lipoprotein research and develop novel genetic therapies for the treatment of cardiovascular disease, this eminently useful book constitutes the new standard reference and guide.

Lipoprotein Analysis

Lipoprotein Analysis
Author: Carolyn A. Converse,E. Roy Skinner
Publsiher: Unknown
Total Pages: 276
Release: 1992
Genre: Lipoproteins
ISBN: UOM:39015028408386

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Lipoproteins play an important role in maintaining the normal distribution of lipids in the body and in the transport of lipophilic compounds. They are also implicated, however, in some of the major diseases of the Western world including atherosclerosis, heart disease, and stroke. This has lead to a dramatic proliferation of lipoprotein research. This comprehensive volume analyzes the biological activity of lipoproteins. It provides detailed protocols for preparing and separating different lipoproteins, and includes methods for studying their metabolism, activity in different tissues, and interactions with receptors. Lipoprotein Analysis: A Practical Approach is an essential manual for all biomedical scientists studying these compounds including those interested in their role in diseases of the circulatory system

Lipoproteins and Cardiovascular Disease

Lipoproteins and Cardiovascular Disease
Author: Lita A. Freeman
Publsiher: Humana
Total Pages: 0
Release: 2016-08-23
Genre: Science
ISBN: 1493956906

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The lipid-rich and otherwise challenging nature of many key tissues complicates many aspects of current research, and applications of the unique nature of lipoproteins and their biological effects has engendered unique and vital methodologies. In Lipoproteins and Cardiovascular Disease: Methods and Protocols, experts in the field present a compendium of advanced and classical molecular biology methods targeted towards lipoprotein, atherosclerosis, and vascular biology research, bringing together in a single volume an updated set of protocols and strategies for methods now driving the most recent advances, along with classical methods that are still widely used. Among the many topics covered in this cutting-edge work, the book delves into crucial techniques such as quantitative real-time PCR, microarrays, RT-PCR laser capture microdissection, and tissue-specific gene overexpression, knockout, and knockdown methodologies, including AAV as a liver-directed gene delivery vehicle. Written in the highly successful Methods in Molecular BiologyTM series format, chapters include introductions to their respective subjects, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and valuable notes which highlight tips on troubleshooting and avoiding known pitfalls. Comprehensive and easy to use, Lipoproteins and Cardiovascular Disease: Methods and Protocols serves both novices and experts alike as a complete guide for any researcher with an interest in lipoproteins and their significant biological effects.

Handbook of Lipoprotein Testing

Handbook of Lipoprotein Testing
Author: Nader Rifai,G. Russell Warnick,Marek H. Dominiczak
Publsiher: Amer. Assoc. for Clinical Chemistry
Total Pages: 848
Release: 2000
Genre: Medical
ISBN: 1890883352

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Protein Lipidation Protocols

Protein Lipidation Protocols
Author: Michael H. Gelb
Publsiher: Springer Science & Business Media
Total Pages: 243
Release: 2008-02-03
Genre: Science
ISBN: 9781592592647

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In Protein Lipidation Protocols, Michael Gelb brings together a collection of readily reproducible techniques for studying protein lipidation, the covalent attachment of lipids to proteins. These cutting-edge methods-many never published before in a "hands-on" format-deal with glycosyl phosphatidylinositol (GPI)-containing compounds, protein fatty acylation, and protein prenylation. Included are novel techniques for determining the chemical structure of GPI-anchors, for radiolabeling the prenyl groups of protein in eukaryotic cells, a tool for developing inhibitors of the protein farnesyltransferase, and for an exciting lysosomal enzyme that cleaves fatty acyl groups from proteins, the first fatty acylase discovered. Protein Lipidation Protocols offers biochemists, cell and molecular biologists, medicinal chemists, and pharmaceutical researchers state-of-the-art tools for understanding the complex biochemistry of protein lipidation, as well as catalyzing the development of many important new biopharmaceuticals, including anticancer drugs.

Management of Dyslipidemia

Management of Dyslipidemia
Author: Wilbert S. Aronow
Publsiher: BoD – Books on Demand
Total Pages: 176
Release: 2021-07-21
Genre: Medical
ISBN: 9781839685071

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Dyslipidemia is a major risk factor for cardiovascular events, cardiovascular mortality, and all-cause mortality. The earlier in life dyslipidemia is treated, the better the prognosis. The current book is an excellent one on dyslipidemia written by experts on this topic. This book includes 12 chapters including 5 on lipids, 4 on hypercholesterolemia in children, and 3 on the treatment of dyslipidemia. This book should be read by all health care professionals taking care of patients, including pediatricians since atherosclerotic cardiovascular disease begins in childhood.

Coronary Primary Prevention Trial

Coronary Primary Prevention Trial
Author: Anonim
Publsiher: Unknown
Total Pages: 2
Release: 1984
Genre: Coronary heart disease
ISBN: MINN:20000004252553

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Clinical Lipidology A Companion to Braunwald s Heart Disease E Book

Clinical Lipidology  A Companion to Braunwald s Heart Disease E Book
Author: Christie M. Ballantyne
Publsiher: Elsevier Health Sciences
Total Pages: 608
Release: 2014-11-14
Genre: Medical
ISBN: 9780323313261

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Clinical Lipidology, a companion to Braunwald’s Heart Disease, is designed to guide you through the ever-changing therapeutic management of patients with high cholesterol levels. From basic science to pathogenesis of atherothrombotic disease, to risk assessment and the latest therapy options, this medical reference book offers unparalleled coverage and expert guidance on lipidology in a straightforward, accessible, and user-friendly style. Get authoritative guidance from some of the foremost experts in the field. Easily access key content with help from treatment algorithms. Access options and evidence-based solutions for every type of patient scenario, as well as the latest clinical guidelines and clinically relevant evidence on risk assessment, special patient populations, and therapy, including recently approved and experimental therapies. Remain at the forefront of the cardiology field with up-to-date chapters on treatment guidelines; diet, exercise, and weight loss; pharmacologic therapies such as statins, omega-3 fatty acids, and combination therapy; evolving targets of therapy such as PCSK9 inhibition, CETP inhibition, and inflammation Prepare for special patient populations such as children and adolescents; women and the elderly; transplant recipients; HIV patients; and those with chronic renal disease, familial hypercholesterolemia, other severe hypercholesterolemias, diabetes, or other metabolic syndromes. Take advantage of a format that follows that of the well-known and internationally recognized Braunwald’s Heart Disease. Consult this title on your favorite e-reader, conduct rapid searches, and adjust font sizes for optimal readability.