Molecular Technologies for Detection of Chemical and Biological Agents

Molecular Technologies for Detection of Chemical and Biological Agents
Author: Joseph H. Banoub,Richard M. Caprioli
Publsiher: Springer
Total Pages: 306
Release: 2017-07-05
Genre: Science
ISBN: 9789402411133

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This book describes the latest molecular insights needed to understand the chemical and biological (CB) agents and their associated biotechnologies. Its primary focus is to present and discuss molecular technologies such as mass spectrometry, chemical and biological sensors, chromatographic and electrophoretic separation, and comparisons of spectroscopic, immunological and molecular analyses of chemicals used for the detection of chemical and biological agents and to prevent terrorism. This NATO-ASI book also contributes to the critical assessment of existing knowledge on new and important detection technologies. It helps to identify directions for future research and to promote closer working relationships between scientists from different professional fields.

Toxic Chemical and Biological Agents

Toxic Chemical and Biological Agents
Author: Giovanni Sindona,Joseph H. Banoub,Maria Luisa Di Gioia
Publsiher: Springer Nature
Total Pages: 282
Release: 2020-10-19
Genre: Science
ISBN: 9789402420418

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This book critically assesses the current state of knowledge on new and important detection technologies, e.g. mass spectrometry, tandem mass spectrometry, biosensor detection and tissue imaging, in connection with toxic chemical and biological agents. In general, the main topics discussed concern the risks and consequences of chemical and biological agents for human health in general, with special emphasis on all biochemical and metabolic pathways including the reproductive system. The exposome, genetic risks and the environment, various health hazard agents, risk assessment, environmental assessment and preparedness, and analysis of sub-lethal effects at the molecular level are also discussed. In closing, the book provides comprehensive information on the diagnosis of exposure, and on health concerns related to toxic chemical and biological agents.

Detection of Biological Agents for the Prevention of Bioterrorism

Detection of Biological Agents for the Prevention of Bioterrorism
Author: Joseph Banoub
Publsiher: Springer Science & Business Media
Total Pages: 360
Release: 2010-11-05
Genre: Science
ISBN: 9789048198795

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The threat of biological and chemical terrorism has driven the demand for timely techniques that can quickly detect the agent or agents used in an attack. The detection and/or prevention of these potential security threats provide significant scientific and technical challenges due to the combination of possible agents and modes of delivery available. This book will present a thorough look at the importance and technological challenges of mass spectrometry (MS) for the detection & identification of biological and chemical threats. This new contribution’s general aims are to draw the attention of recognized practitioners, experts and graduate students trying to grasp the latest MS developments in the cutting-edge fields of MS-biodefense technologies for the rapid/early/specific sensitive threat detection of pathogens, viruses, explosives, mycotoxins, chemical agents, and biological markers of xenobiotic chemicals.

Chemical and Biological Terrorism

Chemical and Biological Terrorism
Author: Committee on R&D Needs for Improving Civilian Medical Response to Chemical and Biological Terrorism Incidents,Institute of Medicine
Publsiher: National Academies Press
Total Pages: 266
Release: 1999-02-26
Genre: History
ISBN: 9780309523141

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The threat of domestic terrorism today looms larger than ever. Bombings at the World Trade Center and Oklahoma City's Federal Building, as well as nerve gas attacks in Japan, have made it tragically obvious that American civilians must be ready for terrorist attacks. What do we need to know to help emergency and medical personnel prepare for these attacks? Chemical and Biological Terrorism identifies the R&D efforts needed to implement recommendations in key areas: pre-incident intelligence, detection and identification of chemical and biological agents, protective clothing and equipment, early recognition that a population has been covertly exposed to a pathogen, mass casualty decontamination and triage, use of vaccines and pharmaceuticals, and the psychological effects of terror. Specific objectives for computer software development are also identified. The book addresses the differences between a biological and chemical attack, the distinct challenges to the military and civilian medical communities, and other broader issues. This book will be of critical interest to anyone involved in civilian preparedness for terrorist attack: planners, administrators, responders, medical professionals, public health and emergency personnel, and technology designers and engineers.

Detection of Chemical Biological Radiological and Nuclear Agents for the Prevention of Terrorism

Detection of Chemical  Biological  Radiological and Nuclear Agents for the Prevention of Terrorism
Author: Joseph Banoub
Publsiher: Springer
Total Pages: 291
Release: 2014-11-03
Genre: Science
ISBN: 9789401792387

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This NATO-ASI installment is designed to provide an advanced overview for doctoral and post-doctoral candidates of the state-of-the-art technologies for bio-detection. The main objective of the work aims at providing readers with the latest developments necessary to successfully understand the CBRN Agents and their associated biotechnologies. The core methods focused on are mass spectrometry (including chromatographic and electrophoretic separation) and comparisons to spectroscopic, immunological and molecular analysis of chemical, biological and nuclear agents.

Bioaerosol Detection Technologies

Bioaerosol Detection Technologies
Author: Per Jonsson,Göran Olofsson,Torbjörn Tjärnhage
Publsiher: Springer
Total Pages: 330
Release: 2014-07-31
Genre: Science
ISBN: 9781441955821

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This book is intended to give technological background and practical examples, but also to give general insight into the on-going technology development in the area of biodetection. The content is therefore suitable for an array of stakeholders (decision makers, purchasing officers, etc.) and end-users of biodetection equipment within the areas of health, environment, safety and security, and military preparation. The book is divided into three sections. The first section discusses the fundamental physical and biological properties of bioaerosol's. The second section goes into more detail and discusses in-depth the most commonly used detection principles. The third section of the book is devoted to technologies that have been used in standoff applications. The last section of the book gives an overview of trends in bioaerosol detection. The reader of this book will gain knowledge about the different biodetection technologies and thus better judge their capabilities in relation to desired applications.

Handbook on Biological Warfare Preparedness

Handbook on Biological Warfare Preparedness
Author: S.J.S. Flora,Vidhu Pachauri
Publsiher: Academic Press
Total Pages: 306
Release: 2019-10-05
Genre: Medical
ISBN: 9780128120552

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Handbook on Biological Warfare Preparedness provides detailed information on biological warfare agents and their mode of transmission and spread. In addition, it explains methods of detection and medical countermeasures, including vaccine and post-exposure therapeutics, with specific sections detailing diseases, their transmission, clinical signs and symptoms, diagnosis, treatment, vaccines, prevention and management. This book is useful reading for researchers and advanced students in toxicology, but it will also prove helpful for medical students, civil administration, medical doctors, first responders and security forces. As the highly unpredictable nature of any event involving biological warfare agents has given rise to the need for the rapid development of accurate detection systems, this book is a timely resource on the topic. Introduces different bacterial and viral agents, including Ebola and other emerging threats and toxins Discusses medical countermeasures, including vaccines and post-exposure therapeutics Includes a comprehensive review of current methods of detection

Commercial and Pre Commercial Cell Detection Technologies for Defence Against Bioterror

Commercial and Pre Commercial Cell Detection Technologies for Defence Against Bioterror
Author: L.M. Lechuga,F.P. Milanovich,P. Skládal
Publsiher: IOS Press
Total Pages: 180
Release: 2008-07-03
Genre: Political Science
ISBN: 9781607503286

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As a response to the rapidly emerging threat of bioterrorism, the objectives of this volume on Commercial and Pre-Commercial Cell Detection Technologies for Defence against Bioterror are to exchange information on commercially available technologies and equipment for defense against bioterrorism; to further the development of new biosensor system prototypes into a commercially available apparatus and to explore human factors in BWA biosensors. The new commercial and pre-commercial technologies that are currently emerging in the world are presented and explained. Furthermore, there is a discussion about the interaction of modern detection systems with society and a trial for improvement of the relation between the scientific community and commercial entities. There are four major areas highlighted: the first is a presentation of the most advanced biosensors and biodetection system which can be found in the market or are quite close to commercialization. Systems as the BIOHAWKTM, SASS 2000, RAPTOR, Bionas® 2500, OWLS, or a portable SPR are presented in this section. The second issue is a presentation of the advances in the research of biodetection devices as DNA and protein microchips, micro and nanophotonic sensors, CMOS microsensor chips, electrochemical arrays, physical platforms, electro optical detection, mass detection, etc. Then, there is a description of the latest developments in the employment of bioreceptor layers for the selective detection of BWA, as protein signatures, molecular imprinted polymers, membrane engineering (MIME), cell signatures, monoclonal antibodies, synthetic antibodies and lytic phages, among others. The last part is the discussion of the human factor: societal issues related to sensor development and employment for BWA detection.