Neuromodulation

Neuromodulation: Comprehensive Textbook of Principles, Technologies, and Therapies, Second Edition, serves as a comprehensive and in-depth reference textbook covering all aspects of the rapidly growing field of neuromodulation. Since the publication of the first edition seven years ago, there has been an explosion of knowledge in neuromodulation, optogenetics, bioelectronics medicine and brain computer interfacing. Users will find unique discussions of the fundamental principles of neuromodulation and therapies, and how they are applied to the brain, spinal cord, peripheral nerves, autonomic nerves and various organs. The book focuses on comprehensive coverage of spinal cord stimulation, non-interventional and interventional brain stimulation, peripheral nerve stimulation, and the emerging fields of neuromodulation, including optogenetics and bioelectronics medicine. Provides a comprehensive reference that covers all aspects of the growing field of neuromodulation Written by international, leading authorities in their respective fields of neuromodulation, pain management, functional neurosurgery and biomedical engineering Includes new chapters on optogenetics, bioelectronics medicine and brain computer interfacing

Neuromodulation will be the first comprehensive and in-depth reference textbook covering all aspects of the rapidly growing field of neuromodulation. This book provides a complete discussion of the fundamental principles of neuromodulation and therapies applied to the brain, spinal cord, peripheral nerves, autonomic nerves and various organs. The textbook is highly structured and organized into overarching sections that cover chronic pain, movement disorders, psychiatric disorders, epilepsy, functional electrical stimulation, cardiac, gastrointestinal, genitourinary and organ neuromodulation. The fundamental principles of electricity and infusion, neural tissue interface, biomedical engineering, neuromodulation devices, basic science, neuroanatomy, neurophysiology, imaging and mechanisms are emphasized. In addition to providing details pertaining to the state-of-the-art current practice, innovative and emerging applications are discussed in specific chapters. Finally, the textbook provides specific chapters focusing on the technical aspects of the various neuromodulation procedures as well as technical specifications of various implantable devices. All of the contributors to Neuromodulation represent leading experts in the field. The editors are internationally renowned in their respective fields of neuromodulation, pain management, functional neurosurgery and biomedical engineering. Neuromodulation will be the first and foremost authoritative text on neuromodulation therapies and will establish the gold standard that defines the field for years to come. Key Features The first comprehensive reference on the emerging field of Neuromodulation Editors and authors include all leading figures in the field, and the leaders of the International Neuromodulation Society Over 90 chapters on topics ranging from a layout of the fundamentals (e.g. neuroanatomy, plasticity, bioelectrical effects, infusion therapies), solutions for the biomedical engineering challenges (e.g. materials, how to preserve normal function etc.), to a rundown of the existing applications and their future promise Over 1200 pages in splendid full color, richly illustrated Important areas of application include: control of chronic pain delivery of drugs to the nervous system via implanted devices control of epilepsy, Parkinson, etc. functional restoration, e.g. visual, auditory, restoration after stroke, restoration of motor function after traumatic events stimulation of body organs via neural devices (incl. the heart, abdominal organs, genitourinary organs) overview over newly emerging fields - control of obesity, blood pressure, tinnitus, brain injury, neurodegenerative diseases, brain-machine interfaces

Until recently, it was thought that the adult brain is modifiable only during early stages of ontogenesis. However, neurophysiological and neuroimaging studies now indicate that the mature human brain is, under certain conditions, capable of substantial neuroplastic changes. Neuroplasticity reflects the ability of the human brain to alter the pattern of neural activation in response to previous experience, and recent findings indicate that the effects of experience can lead to both structural as well as functional reorganization. It has been shown that pathological neuroplastic changes can be reverted/normalized and that the modulation of the neuroplastic changes can be paralleled by improvement of the patient's status. However, there is a gap between the potential of neuromodulation, technical progress and actual preparedness of medical personnel to provide this type of treatment. A prevalent opinion among medical professionals indicates that training programs and educational materials in neuromodulatory techniques are well needed and appreciated. Neuromodulation will focus on the description and discussion of methods currently available for invasive and non-invasive neuromodulation, their clinical potential, significance and practical applications. In order to facilitate understanding of the topic, the initial part of the textbook will review neurophysiological systems involved in neuromodulation and will provide readers with basic principles of neuroplasticity that constitutes the rationale for neuromodulation in human medicine. Additionally, the clinical use of these techniques will be described with special regard to safety and avoidance of complications.

The study of neurofeedback and neuromodulation offer a window into brain physiology and function, suggesting innovative approaches to the improvement of attention, anxiety, pain, mood and behavior. Resources for understanding what neurofeedback and neuromodulation are, how they are used, and to what disorders and patients they can be applied are scarce, and this volume serves as an ideal tool for clinical researchers and practicing clinicians in both neuroscience and psychology to understand techniques, analysis, and their applications to specific patient populations and disorders. The top scholars in the field have been enlisted, and contributions offer both the breadth needed for an introductory scholar and the depth desired by a clinical professional. Includes the practical application of techniques to use with patients Includes integration of neurofeedback with neuromodulation techniques Discusses what the technique is, for which disorders it is effective, and the evidence basis behind its use Written at an appropriate level for clinicians and researchers

Among neuromodulation procedures, electrical stimulation of peripheral nerves (PNS) is probably the most underappreciated modality. Although PNS is used for all kinds of medical conditions, ranging from chronic neuropathic pain and headache to epilepsy, depression, hypertension and heart failure, its importance is frequently overshadowed by spinal cord stimulation and deep brain stimulation. While the earlier version of this book dealt exclusively with various pain syndromes, this new volume covers the entire spectrum of PNS applications. Written by recognized authorities in their respective fields, the chapters of this title describe the use of PNS in the management of neurological, psychiatric, otorhinolaryngological, cardiovascular, pulmonary, colorectal and genitourinary disorders. To reflect the complexity of the regulatory process, the book ends with a special chapter dedicated to the current state of approval of different PNS devices. This book will be of great value to all those who deal with neuromodulation, including clinicians who select PNS candidates, surgeons and other specialists who implant PNS devices, and researchers and engineers who work on making the stimulators safer and more effective.

Neuromodulation is an emerging field that explores the use of electrical, chemical, and mechanical interventions to heal neurological deficits. Such neurostimulation has already shown great promise with disorders and diseases such as chronic pain, epilepsy, and Parkinson’s disease. This is the first concise reference covering all of the basic principles of neuromodulation in a single affordable volume for neuro-residents, fellows, and basic clinical practitioners, edited by two prominent clinical experts in the field. This volume emphasizes essential observations from all of the important clinical phases involved in any neuromodulation: targeting, intraoperative assessment, programming, complications, and complication avoidance. There are commonalities to all neuromodulation procedures that must be brought to the forefront to form a cohesive presentation of neuromodulation, and such emphasis will give readers a more solid grounding in the fundamentals needed to embrace this field as a cohesive clinical entity. Chapters offer point-counterpoint commentary for varied perspectives Appendix distills current guidelines in easy, accessible format Chapters follow story of patient care, effectively emphasizing general principles with supporting examples Offers outstanding scholarship, with over 20% of chapters involving international contributors

Essentials of Neuromodulation describes the application of neuromodulation for aesthetic purposes. Detailed for readers are all essential aspects of neuromodulation treatment, including how to best safeguard patients. This volume provides an increased anatomical understanding of the injection anatomy within the face in an effort to focus on standard of care and set an industry standard in cosmetic injectables. Given the highly specialized training required for this skill, it details the history as well as the mechanism of action for each FDA-approved neuromodulating drug on the market. Unique anatomical renderings by medical artist Kevin Cease provide accurate and detailed anatomy to correlate beautifully with the content. With before, during, and after photos of more than 20 models and written detailed descriptions, diagrams, tables, and charts, all types of learners with every style of learning will benefit from this one-of-a-kind book. This book is a stepping stone for in-depth knowledge into this specialty field and begin to set the standard for entrance into the practice of aesthetics. Provides a broad background to the neuroaesthetics field, including definitions Highlights key brain regions involved in processing aesthetic experiences Uniquely discusses neuroaesthetics in the context of brain plasticity Features over 20 unique anatomical presentations to help master neuromodulation Describes techniques and explores data from brain-imaging technology

Offers expert guidance on functional neurosurgery and neuromodulation, lists of requirements, and the instruments needed to perform these procedures. Answers practical questions such as "What do I need when performing a thermal procedure?", "What do I need to bear in mind when assembling a device?", and "What do I need to remember with regards to voltages, electrodes, percutaneous leads, RF generators, imaging, and micro instruments?" Consolidates today’s available information and guidance in this timely area into one convenient resource. Functional Neurosurgery and Neuromodulation provides comprehensive coverage of this emerging, minimally invasive area of health care. Recent advances in these areas have proven effective for pain relief, memory loss, addiction, and much more. This practical resource by Drs. Kim J. Burchiel and Ahmed Raslan brings you up to date with what’s new in the field and how it can benefit your patients.