Non Canonical Autophagy

Non Canonical Autophagy
Author: Giulia Petroni,Lorenzo Galluzzi
Publsiher: Academic Press
Total Pages: 184
Release: 2021-04-21
Genre: Science
ISBN: 9780128209110

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Non-canonical Autophagy: Mechanisms and Pathophysiological Implications outlines the differences between ‘canonical’ and ‘non-canonical’ forms of autophagy, highlighting the discoveries concerning the molecular mechanisms underlying these unconventional forms of autophagy and the advancements in pathophysiological features of ‘non-canonical’ autophagy. The book discusses all forms of ‘non-canonical’ autophagy and the complexity of autophagy-dependent cell death. Readers will gain a better understanding of mechanisms underlying ‘non-canonical’ autophagy so that they can interpret the biological effects of autophagy correctly and identify reliable, novel and effective treatment strategies. Presents the most advanced information surrounding the molecular mechanisms underlying non-canonical autophagy Outlines the increasing evidence regarding the involvement of non-canonical autophagy in multiple physiological and pathological processes Discusses the therapeutic potential of autophagy modulators and the obstacles that have limited their development

Membrane Biogenesis

Membrane Biogenesis
Author: Jos A.F. Op den Kamp
Publsiher: Springer Science & Business Media
Total Pages: 474
Release: 2013-06-29
Genre: Science
ISBN: 9783642731846

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Many individual aspects of the dynamics and assembly of biological membranes have been studied in great detail. Cell biological approaches, advanced genetics, biophysics and biochemistry have greatly contributed to an increase in our knowledge in this field.lt is obvious however, that the three major membrane constituents - lipids, proteins and carbohydrates- are studied, in most cases separately and that a coherent overview of the various aspects of membrane biogenesis is not readily available. The NATO Advanced Study Institute on "New Perspectives in the Dynamics of Assembly of Biomembranes" intended to provide such an overview: it was set up to teach students and specialists the achievements obtained in the various research areas and to try and integrate the numerous aspects of membrane assembly into a coherent framework. The articles in here reflect this. Statting with detailed contributions on phospholipid structure, dynamics, organization and biogenesis, an up to date overview of the basic, lipidic backbone of biomembranes is given. Extensive progress is made in the research on membrane protein biosynthesis. In particular the post- and co-translational modification processes of proteins, the mechanisms of protein translocation and the sorting mechanisms which are necessary to direct proteins to their final, intra - or extracellular destination have been characterized in detail. Modern genetic approaches were indispensable in this research area: gene cloning, hybrid protein construction, site directed mutagenesis and sequencing techniques elucidated many functional aspects of specific nucleic acid and amino acid sequences.

Autophagy in Health and Disease

Autophagy in Health and Disease
Author: Roberta A. Gottlieb
Publsiher: Academic Press
Total Pages: 241
Release: 2012-10-16
Genre: Health & Fitness
ISBN: 9780123851017

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Richly illustrated and referenced.

Autophagy in Autoimmunity

Autophagy in Autoimmunity
Author: Xu-jie Zhou,Panayotis Verginis,Jennifer Martinez,Marko Radic
Publsiher: Frontiers Media SA
Total Pages: 161
Release: 2019-05-15
Genre: Electronic Book
ISBN: 9782889458127

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Plant Cell Membranes

Plant Cell Membranes
Author: Lester Packer,Roland Douce
Publsiher: Academic Press
Total Pages: 806
Release: 1987-11-28
Genre: Nature
ISBN: UCSD:31822033947557

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The critically acclaimed laboratory standard, Methods in Enzymology, is one of the most highly respected publications in the field of biochemistry. Since 1955, each volume has been eagerly awaited, frequently consulted, and praised by researchers and reviewers alike. The series contains much material still relevant today - truly an essential publication for researchers in all fields of life sciences.

Autophagy of the Nervous System

Autophagy of the Nervous System
Author: Zhenyu Yue,Charleen T. Chu
Publsiher: World Scientific
Total Pages: 441
Release: 2012
Genre: Medical
ISBN: 9789814350440

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What is autophagy? Why would neurons digest parts of themselves through autophagy? How can autophagy save the lives of cells under some conditions, but act as an accomplice to cell death in others? By what mechanisms are autophagy-related processes dysregulated in neurological diseases, and are there therapeutic strategies to correct or compensate for their dysfunction? This book provides an expert view of major concepts in autophagy research with a focus on autophagy in neurons. Experimental evidence for evolutionarily conserved and specialized regulatory mechanisms for autophagy in the mammalian nervous system will be presented, including recent data on braking mechanisms. Areas of intersection with cell death, the ubiquitin-proteasome system, chaperone-mediated autophagy, and the endocytic pathway will be reviewed, along with emerging areas of mitochondrial autophagy (mitophagy) and the autophagic regulation of neuritic/synaptic processes. Advances in delineating mechanisms by which autophagy is involved in the pathophysiology of neurological disorders, including Alzheimer's, Parkinson's, Huntington's, amyotrophic lateral sclerosis, ischemia/hypoxia and lysosomal storage diseases, will be discussed along with current drug development strategies targeting autophagy.

The Role of Autophagy in Infectious Diseases

The Role of Autophagy in Infectious Diseases
Author: Hua Niu,Meihong Deng
Publsiher: Frontiers Media SA
Total Pages: 183
Release: 2022-11-08
Genre: Science
ISBN: 9782832504260

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A year in review Discussions in autoimmune and autoinflammatory disorders

A year in review  Discussions in autoimmune and autoinflammatory disorders
Author: Raphaela Goldbach-Mansky,Betty Diamond
Publsiher: Frontiers Media SA
Total Pages: 173
Release: 2023-03-31
Genre: Medical
ISBN: 9782832519387

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