Pandemics Pills And Politics

Encapsulating security : pharmaceutical defenses against biological danger -- Discovering a virus's achilles heel : flu fighting at molecular scale -- The pill always wins: Gilead Sciences, Roche and the birth of Tamiflu -- What a difference a day makes : the margin call for regulatory agencies -- Virtual blockbuster : bird flu and the pandemic of preparedness planning -- In the eye of the storm : global access, generics and intellectual property -- 'Ode to Tamiflu' : side effects, teenage 'suicides' and corporate liabilities -- Data backlash : Roche and Cochrane square up over clinical trial data -- 'To boldly go ... ' : pharmaceutical enterprises and global health security -- Epilogue : pharmaceuticals, security and molecular life

Two of America's leading national security experts offer a definitive account of the global impact of COVID-19 and the political shock waves it will have on the United States and the world order in the 21st Century. “Informed by history, reporting, and a truly global perspective, this is an indispensable first draft of history and blueprint for how we can move forward.” —Ben Rhodes The COVID-19 pandemic killed millions, infected hundreds of millions, and laid bare the deep vulnerabilities and inequalities of our interconnected world. The accompanying economic crash was the worst since the Great Depression, with the International Monetary Fund estimating that it will cost over $22 trillion in global wealth over the next few years. Over two decades of progress in reducing extreme poverty was erased, just in the space of a few months. Already fragile states in every corner of the globe were further hollowed out. The brewing clash between the United States and China boiled over and the worldwide contest between democracy and authoritarianism deepened. It was a truly global crisis necessitating a collective response—and yet international cooperation almost entirely broke down, with key world leaders hardly on speaking terms. Colin Kahl and Thomas Wright's Aftershocks offers a riveting and comprehensive account of one of the strangest and most consequential years on record. Drawing on interviews with officials from around the world and extensive research, the authors tell the story of how nationalism and major power rivalries constrained the response to the worst pandemic in a century. They demonstrate the myriad ways in which the crisis exposed the limits of the old international order and how the reverberations from COVID-19 will be felt for years to come.

Over the past few decades a number of emerging infectious diseases (EIDs) have disrupted societies throughout the world, including HIV, Ebola, H5N1 (or ‘‘avian flu’’) and SARS, and of course the coronavirus disease (COVID-19) which spread worldwide to become a global pandemic. As well as EIDs, countries and regions also contend with endemic diseases, such as malaria. There are many factors that have contributed to the rise in, and spread of, EIDs and other diseases, including overpopulation, rapid urbanization, environmental degradation, and antibiotic resistance. Political and cultural responses to disease can greatly affect their spread. The global community needs to defend itself against disease threats: one weak link is enough to start a chain reaction that results in a global pandemic such as COVID-19. Some states take a nationalistic approach towards combating disease; however, international cooperation and meaningful ‘‘viral sovereignty’’—empowering countries to create effective health institutions and surveillance systems in order to contain disease—must be considered. This volume, with a focus on Southeast Asia, Africa and North America, considers the intersection between disease, politics, science, and culture in the global battle against pandemics, making use of case studies and interviews to examine the ways in which governments and regions handle outbreaks and pandemics.

Providing an immediate, contemporary example of a region networking its response to disease outbreak events, this insightful book will appeal to global health governance scholars, students, and practitioners.

̀This is an excellent book which provides an authoritative introduction to the subject coupled with challenging and original new line of thinking about the problem of securing global health.' Colin McInnes, Aberystwyth University --

Drug overdose, driven largely by overdose related to the use of opioids, is now the leading cause of unintentional injury death in the United States. The ongoing opioid crisis lies at the intersection of two public health challenges: reducing the burden of suffering from pain and containing the rising toll of the harms that can arise from the use of opioid medications. Chronic pain and opioid use disorder both represent complex human conditions affecting millions of Americans and causing untold disability and loss of function. In the context of the growing opioid problem, the U.S. Food and Drug Administration (FDA) launched an Opioids Action Plan in early 2016. As part of this plan, the FDA asked the National Academies of Sciences, Engineering, and Medicine to convene a committee to update the state of the science on pain research, care, and education and to identify actions the FDA and others can take to respond to the opioid epidemic, with a particular focus on informing FDA's development of a formal method for incorporating individual and societal considerations into its risk-benefit framework for opioid approval and monitoring.

The COVID-19 pandemic isn’t over. But even as governments around the world try to get it under control, they’re also starting to talk about what happens next. How can we prevent another pandemic from killing millions of people and devastating the global economy? Can we even hope to accomplish this? Bill Gates believes the answer is yes, and he has written a largely upbeat book that lays out clearly and convincingly what the world should learn from COVID-19, explains the science of fighting pandemics, and suggests what all of us can do to help prevent another one.

Touching on a range of disease, from leishmaniasis, schistosomiasis, and Middle East Respiratory Syndrome (MERS) to COVID-19, Preventing the Next Pandemic has always been a timely goal, but it will be even more important in a COVID and post-COVID world.