Parasite Rex

A look inside the often hidden world of parasites turns the clock back to the beginning of life on Earth to answer key questions about these highly evolved and resilient life forms.

Dickson D. Despommier's vivid, visceral account of the biology, behavior, and history of parasites follows the interplay between these fascinating life forms and human society over thousands of years. Despommier focuses on long-term host-parasite associations, which have evolved to avoid or even subvert the human immune system. Some parasites do great damage to their hosts, while others have signed a kind of "peace treaty" in exchange for their long lives within them. Many parasites also practice clever survival strategies that medical scientists hope to mimic as they search for treatments for Crohn's disease, food allergies, type 1 diabetes, organ transplantation, and other medical challenges. Despommier concentrates on particularly remarkable and often highly pathogenic organisms, describing their lifecycles and the mechanisms they use to avoid elimination. He details their attack and survival plans and the nature of the illnesses they cause in general terms, enabling readers of all backgrounds to steal a glimpse into the secret work of such effective invaders. He also points to the cultural contexts in which these parasites thrive and reviews the current treatments available to defeat them. Encouraging scientists to continue to study these organisms even if their threat is largely contained, Despommier shows how closer dissection of the substances parasites produce to alter our response to them could help unravel some of our most complex medical conundrums.

The evolution and life history of parasites, their role in shaping human history, as well as future threats posed by them.

“Engrossing … [An] expedition through the hidden and sometimes horrifying microbial domain.” —Wall Street Journal “Fascinating—and full of the kind of factoids you can't wait to share.” —Scientific American Parasites can live only inside another animal and, as Kathleen McAuliffe reveals, these tiny organisms have many evolutionary motives for manipulating the behavior of their hosts. With astonishing precision, parasites can coax rats to approach cats, spiders to transform the patterns of their webs, and fish to draw the attention of birds that then swoop down to feast on them. We humans are hardly immune to their influence. Organisms we pick up from our own pets are strongly suspected of changing our personality traits and contributing to recklessness and impulsivity—even suicide. Germs that cause colds and the flu may alter our behavior even before symptoms become apparent. Parasites influence our species on the cultural level, too. Drawing on a huge body of research, McAuliffe argues that our dread of contamination is an evolved defense against parasites. The horror and revulsion we are programmed to feel when we come in contact with people who appear diseased or dirty helped pave the way for civilization, but may also be the basis for major divisions in societies that persist to this day. This Is Your Brain on Parasites is both a journey into cutting-edge science and a revelatory examination of what it means to be human. “If you’ve ever doubted the power of microbes to shape society and offer us a grander view of life, read on and find yourself duly impressed.” —Heather Havrilesky, Bookforum

Synthesizes the latest developments in the ecology and evolution of animal parasites for a new generation of parasitologists.

A Best Book of the YearSeed Magazine • Granta Magazine • The Plain-DealerIn this fascinating and utterly engaging book, Carl Zimmer traces E. coli's pivotal role in the history of biology, from the discovery of DNA to the latest advances in biotechnology. He reveals the many surprising and alarming parallels between E. coli's life and our own. And he describes how E. coli changes in real time, revealing billions of years of history encoded within its genome. E. coli is also the most engineered species on Earth, and as scientists retool this microbe to produce life-saving drugs and clean fuel, they are discovering just how far the definition of life can be stretched.

The medical tapestry of the world is full of organisms too small to see, carried by flying and creeping creatures too numerous to eradicate. A while ago, DDT and the antimalarial drug chloroquine seemed sure to make us all safe from such invisible assault. It was not to be. The mosquito has become resistant to DDT; malaria is on the rise; although tapeworms rarely turn up any longer in the most lovingly prepared New York City gefilte fish, a worm may inhabit your sashimi; some strains of gonorrhea actually thrive on penicillin; there is even a parasite for the higher tax brackets—the "nymph of Nantucket"; and there are new ailments—legionnaire's disease, Lassa fever, and new strains of influenza. In the long run, one might bet on the insects and the germs. Meanwhile Dr. Robert Desowitz has written a delightful and instructive book.

Everybody Out of the Pond At the Water's Edge will change the way you think about your place in the world. The awesome journey of life's transformation from the first microbes 4 billion years ago to Homo sapiens today is an epic that we are only now beginning to grasp. Magnificent and bizarre, it is the story of how we got here, what we left behind, and what we brought with us. We all know about evolution, but it still seems absurd that our ancestors were fish. Darwin's idea of natural selection was the key to solving generation-to-generation evolution -- microevolution -- but it could only point us toward a complete explanation, still to come, of the engines of macroevolution, the transformation of body shapes across millions of years. Now, drawing on the latest fossil discoveries and breakthrough scientific analysis, Carl Zimmer reveals how macroevolution works. Escorting us along the trail of discovery up to the current dramatic research in paleontology, ecology, genetics, and embryology, Zimmer shows how scientists today are unveiling the secrets of life that biologists struggled with two centuries ago. In this book, you will find a dazzling, brash literary talent and a rigorous scientific sensibility gracefully brought together. Carl Zimmer provides a comprehensive, lucid, and authoritative answer to the mystery of how nature actually made itself.