Quasispecies and RNA Virus Evolution

Quasispecies and RNA Virus Evolution
Author: Esteban Domingo
Publsiher: Unknown
Total Pages: 188
Release: 2001
Genre: Molecular evolution
ISBN: 1587060108

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The Evolution and Emergence of RNA Viruses

The Evolution and Emergence of RNA Viruses
Author: Edward C. Holmes
Publsiher: Oxford University Press
Total Pages: 267
Release: 2009-06-25
Genre: Language Arts & Disciplines
ISBN: 9780199211128

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While the study of viral evolution has developed rapidly in the last 30 years, little attention has been directed toward linking the mechanisms of viral evolution to the epidemiological outcomes of these processes. This book intends to fill this gap by considering the patterns and processes of viral evolution at all its spatial and temporal scales.

Virus as Populations

Virus as Populations
Author: Esteban Domingo
Publsiher: Academic Press
Total Pages: 426
Release: 2019-11-06
Genre: Science
ISBN: 9780128163320

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Virus as Composition, Complexity, Quasispecies, Dynamics, and Biological Implications, Second Edition, explains the fundamental concepts surrounding viruses as complex populations during replication in infected hosts. Fundamental phenomena in virus behavior, such as adaptation to changing environments, capacity to produce disease, and the probability to be transmitted or respond to treatment all depend on virus population numbers. Concepts such as quasispecies dynamics, mutations rates, viral fitness, the effect of bottleneck events, population numbers in virus transmission and disease emergence, and new antiviral strategies are included. The book's main concepts are framed by recent observations on general virus diversity derived from metagenomic studies and current views on the origin and role of viruses in the evolution of the biosphere. Features current views on key steps in the origin of life and origins of viruses Includes examples relating ancestral features of viruses with their current adaptive capacity Explains complex phenomena in an organized and coherent fashion that is easy to comprehend and enjoyable to read Considers quasispecies as a framework to understand virus adaptability and disease processes

Origin and Evolution of Viruses

Origin and Evolution of Viruses
Author: Esteban Domingo,Colin R. Parrish,John J. Holland
Publsiher: Elsevier
Total Pages: 573
Release: 2008-06-23
Genre: Science
ISBN: 9780080564968

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New viral diseases are emerging continuously. Viruses adapt to new environments at astounding rates. Genetic variability of viruses jeopardizes vaccine efficacy. For many viruses mutants resistant to antiviral agents or host immune responses arise readily, for example, with HIV and influenza. These variations are all of utmost importance for human and animal health as they have prevented us from controlling these epidemic pathogens. This book focuses on the mechanisms that viruses use to evolve, survive and cause disease in their hosts. Covering human, animal, plant and bacterial viruses, it provides both the basic foundations for the evolutionary dynamics of viruses and specific examples of emerging diseases. NEW - methods to establish relationships among viruses and the mechanisms that affect virus evolution UNIQUE - combines theoretical concepts in evolution with detailed analyses of the evolution of important virus groups SPECIFIC - Bacterial, plant, animal and human viruses are compared regarding their interation with their hosts

Quasispecies Concept and Implications for Virology

Quasispecies  Concept and Implications for Virology
Author: Esteban Domingo
Publsiher: Springer Science & Business Media
Total Pages: 410
Release: 2006-02-19
Genre: Medical
ISBN: 9783540263975

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Continuous genetic variation and selection of virus subpopulations in the course of RNA virus replications are intimately related to viral disease mechanisms. The central topics of this volume are the origins of the quasispecies concept, and the implications of quasispecies dynamics for viral populations.

Quasispecies and RNA Virus Evolution

Quasispecies and RNA Virus Evolution
Author: Anonim
Publsiher: Unknown
Total Pages: 173
Release: 2001
Genre: RNA viruses
ISBN: 1570596557

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Viruses Essential Agents of Life

Viruses  Essential Agents of Life
Author: Günther Witzany
Publsiher: Springer Science & Business Media
Total Pages: 428
Release: 2012-11-13
Genre: Science
ISBN: 9789400748996

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A renaissance of virus research is taking centre stage in biology. Empirical data from the last decade indicate the important roles of viruses, both in the evolution of all life and as symbionts of host organisms. There is increasing evidence that all cellular life is colonized by exogenous and/or endogenous viruses in a non-lytic but persistent lifestyle. Viruses and viral parts form the most numerous genetic matter on this planet.

Viruses

Viruses
Author: Michael G. Cordingley
Publsiher: Harvard University Press
Total Pages: 385
Release: 2017-06-19
Genre: Medical
ISBN: 9780674972087

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While viruses—the world’s most abundant biological entities—are not technically alive, they invade, replicate, and evolve within living cells. Michael Cordingley goes beyond our familiarity with infections to show how viruses spur evolutionary change in their hosts and shape global ecosystems, from ocean photosynthesis to drug-resistant bacteria.