Selective Glycosylations

Selective Glycosylations
Author: Clay S. Bennett
Publsiher: John Wiley & Sons
Total Pages: 400
Release: 2017-01-19
Genre: Science
ISBN: 9783527696246

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A comprehensive summary of novel approaches to the stereoselective construction of glycosidic linkages, covering modern glycosylation methods and their use and application in natural product synthesis and drug discovery. Clearly divided into five sections, the first describes recent advances in classical methodologies in carbohydrate chemistry, while the second goes on to deal with newer chemistries developed to control selectivity in glycosylation reactions. Section three is devoted to selective glycosylation reactions that rely on the use of catalytic promoters. Section four describes modern approaches for controlling regioselectivity in carbohydrate synthesis. The final section focuses on new developments in the construction of "unusual" sugars and is rounded off by a presentation of modern procedures for the construction of glycosylated natural products. By providing the latest advances in glycosylation as well as information on mechanistic aspects of the reaction, this is an invaluable reference for both specialists and beginners in this booming interdisciplinary field that includes carbohydrate chemistry, organic synthesis, catalysis, and biochemistry.

Handbook of Chemical Glycosylation

Handbook of Chemical Glycosylation
Author: Alexei V. Demchenko
Publsiher: John Wiley & Sons
Total Pages: 524
Release: 2008-04-09
Genre: Science
ISBN: 9783527621651

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Since carbohydrate oligomers are still a challenge in synthetic chemistry, this book on recent developments fulfils a great need. Covering the chemistry necessary to synthesize exact copies of these structures, top authors from all around the world comprehensively deal with synthesis from anomeric halides, from miscellaneous glycosyl donors, and by indirect and special methods, as well as 1-oxygen-and 1-sulfur-substituted derivatives. They demonstrate the best approach for the stereoselective formation of the intermonomeric bond, making this essential reading for every biochemist working in biosynthesis, the exploration of biopathways and vaccines.

Reactivity Tuning in Oligosaccharide Assembly

Reactivity Tuning in Oligosaccharide Assembly
Author: Bert Fraser-Reid,J. Cristóbal López
Publsiher: Springer
Total Pages: 296
Release: 2011-05-11
Genre: Science
ISBN: 9783642209147

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Armed–Disarmed Effects in Carbohydrate Chemistry: History, Synthetic and Mechanistic Studies, by Bert Fraser-Reid and J. Cristóbal López * A Survey of Ley’s Reactivity Tuning in Oligosaccharide Synthesis, by Ana M. Gómez * “Active–Latent” Thioglycosyl Donors and Acceptors in Oligosaccharide Syntheses, by Tze Chieh Shiao and René Roy * Effect of Electron-Withdrawing Protecting Groups at Remote Positions of Donors on Glycosylation Stereochemistry, by Kwan Soo Kim and Dae-Hwan Suk * Influence of Protecting Groups on the Reactivity and Selectivity of Glycosylation: Chemistry of the 4,6-O-Benzylidene Protected Mannopyranosyl Donors and Related Species, by Sylvain Aubry, Kaname Sasaki, Indrajeet Sharma and David Crich * Superarmed and Superdisarmed Building Blocks in Expeditious Oligosaccharide Synthesis, by Hemali D. Premathilake and Alexei V. Demchenko * Programmable One-Pot Glycosylation, by Chung -Yi Wu and Chi -Huey Wong * Uronic Acids in Oligosaccharide and Glycoconjugate Synthesis, by Jeroen D. C. Codée, Alphert E. Christina, Marthe T. C. Walvoort, Herman S. Overkleeft and Gijsbert A. van der Marel

Essentials of Glycobiology

Essentials of Glycobiology
Author: Ajit Varki,Maarten J. Chrispeels
Publsiher: CSHL Press
Total Pages: 694
Release: 1999
Genre: Medical
ISBN: 0879696818

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Sugar chains (glycans) are often attached to proteins and lipids and have multiple roles in the organization and function of all organisms. "Essentials of Glycobiology" describes their biogenesis and function and offers a useful gateway to the understanding of glycans.

Glycochemical Synthesis

Glycochemical Synthesis
Author: Shang-Cheng Hung,Medel Manuel L. Zulueta
Publsiher: John Wiley & Sons
Total Pages: 576
Release: 2016-09-12
Genre: Science
ISBN: 9781119006473

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This book is a comprehensive and concise review on principles, strategies, and crucial advances in glycochemistry. It focuses on synthesis and practical applications and emphasizes state-of-the-art approaches to the assembly and design of sugars. • Provides detailed discussion on specific topics like oligosaccharide assembly and design of sugars, techniques in glycoconjugate preparation, multivalency, and carbohydrate-based drug design • Uses notable examples, like solution-based one-pot methods and automated methods for sugar assembly, to illustrate important concepts and advances in a rapidly emerging field • Discusses practical applications of carbohydrates, like medicine, therapeutics, drug and vaccine development

Glycoscience

Glycoscience
Author: Bertram O. Fraser-Reid,Kuniaki Tatsuta,Joachim Thiem
Publsiher: Springer Science & Business Media
Total Pages: 2847
Release: 2008-04-14
Genre: Science
ISBN: 9783540361541

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As a reflection of the quantum leap that has been made in the study of glycostructures, the first edition of this book has been completely revised and updated. The editors give up-to-date information on glycostructures, their chemistry and chemical biology in the form of a completely comprehensive survey. Glycostructures play highly diverse and crucial roles in a myriad of organisms and important systems in biology, physiology, medicine, bioengineering and technology. Only in recent years have the tools been developed to partly understand the highly complex functions and the chemistry behind them. While many facts remain undiscovered, this MRW has been contributed to by a large number of the world’s leading researchers in the field.

Carbohydrate Chemistry Volume 45

Carbohydrate Chemistry Volume 45
Author: Yves Queneau,Thisbe K. Lindhorst,Amelia Pilar Rauter
Publsiher: Royal Society of Chemistry
Total Pages: 713
Release: 2021-12-22
Genre: Science
ISBN: 9781839163906

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Carbohydrate Chemistry is an invaluable volume demonstrating the interdisciplinary nature of modern carbohydrate research and containing analysed, evaluated and distilled information on the latest research in the area.

I Stereoselective N glycosylation by Staudinger Ligation

I  Stereoselective N glycosylation by Staudinger Ligation
Author: Yi He
Publsiher: Unknown
Total Pages: 324
Release: 2005
Genre: Electronic Book
ISBN: WISC:89091720276

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