How to Make a Vaccine

How to Make a Vaccine
Author: John Rhodes
Publsiher: University of Chicago Press
Total Pages: 185
Release: 2021-04-12
Genre: Medical
ISBN: 9780226792651

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Distinguished expert in vaccine development John Rhodes tells the story of the first approved COVID-19 vaccines and offers an essential, up-to-the-minute primer on how scientists discover, test, and distribute vaccines. As the COVID-19 pandemic has affected every corner of the world, changing our relationship to our communities, to our jobs, and to each other, the most pressing question has been—when will it end? Researchers around the globe are urgently trying to answer this question by racing to test and distribute a vaccine that could end the greatest public health threat of our time. In How to Make a Vaccine, an expert who has firsthand experience developing vaccines tells an optimistic story of how three hundred years of vaccine discovery and a century and a half of immunology research have come together at this powerful moment—and will lead to multiple COVID-19 vaccines. Dr. John Rhodes draws on his experience as an immunologist, including working alongside a young Anthony Fauci, to unravel the mystery of how vaccines are designed, tested, and produced at scale for global deployment. Concise and accessible, this book describes in everyday language how the immune system evolved to combat infection, how viruses responded by evolving ways to evade our defenses, and how vaccines do their work. That history, and the pace of current research developments, make Rhodes hopeful that multiple vaccines will protect us. Today the complex workings of the immune system are well understood. The tools needed by biomedical scientists stand ready to be used, and more than 160 vaccine candidates have already been produced. But defeating COVID-19 won’t be the end of the story: Rhodes describes how discoveries today are also empowering scientists to combat future threats to global health, including a recent breakthrough in the development of genetic vaccines, which have never before been used in humans. As the world prepares for a vaccine, Rhodes offers a current and informative look at the science and strategies that deliver solutions to the crisis.

Health Dimensions of COVID 19 in India and Beyond

Health Dimensions of COVID 19 in India and Beyond
Author: Saroj Pachauri,Ash Pachauri
Publsiher: Springer Nature
Total Pages: 370
Release: 2022
Genre: COVID-19 (Disease)
ISBN: 9789811673856

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This open access book addresses the multiple health dimensions posed by the COVID-19 pandemic in India and other countries including nine in Asia, five in Sub-Saharan Africa, and New Zealand. It explores the impact of the pandemic on mental health, sexual and reproductive health and rights, health financing, self-care, and vaccine development and distribution. The contributing authors discuss its impact on vulnerable populations, including interstate migrants and female sex workers. The significant role of media and communications, rapid dissemination of information in social media, and its impact during the COVID-19 pandemic era are discussed. It closes with lessons learned from the experiences of countries that have contained the pandemic. With contributions from experts from around the world, this book presents solutions of problems that relate to COVID-19. It is a valuable resource appealing to a wide readership across the social sciences and the humanities. Readers include governments, academicians, researchers, policy-makers, program implementers, as well as lay persons.

Vaccines and Immunization Services During the Pandemic Era and Beyond

Vaccines and Immunization Services During the Pandemic Era and Beyond
Author: Edina Amponsah-Dacosta,Oghenebrume Wariri,Anthony Afum-Adjei Awuah,Alma Fulurija
Publsiher: Frontiers Media SA
Total Pages: 177
Release: 2024-03-28
Genre: Medical
ISBN: 9782832546758

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Covid 19 and Vaccine Nationalism

Covid 19 and Vaccine Nationalism
Author: Eric E. Otenyo
Publsiher: Elsevier
Total Pages: 320
Release: 2023-02-18
Genre: Science
ISBN: 9780443185717

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Covid-19 and Vaccine Nationalism: Managing the Politics of Global Pandemics provides an in-depth overview of the complex nature politics played in vaccine production and distribution. The book ensures international and domestic politics, governance, and mechanisms of vaccine production and administration are understandable through insightful discussions. The book aims to solve several problems, including the essence of vaccine nationalism in a context of international politics, the discourse of vaccine nationalism outside popular media, historical documentation of the problem of vaccine inequality and low access of Covid-19 vaccines in developing countries of Africa, the Caribbean, parts of Asia, and more. Final sections cover the global blueprint of solving the problem of the Covid-19 pandemic through vaccines and an in-depth analysis of the politics of Covid-19 vaccines in the United States, China, Europe, the United Kingdom and India. Includes brief descriptions of the political and historical content of various countries accused of practicing vaccine nationalism Provides insightful reasons and responses to the national and regional strategies developed in the global vaccine management process Offers insights into how future pandemics may avoid mistakes made by policymakers

Potency Assays for Advanced Stem Cell Therapy Medicinal Products

Potency Assays for Advanced Stem Cell Therapy Medicinal Products
Author: Jorge S. Burns
Publsiher: Springer Nature
Total Pages: 226
Release: 2023-05-31
Genre: Science
ISBN: 9783031300400

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This volume of the Springer book series Advances in Experimental Medicine and Biology covers potency assays, one of the most complex yet fundamental evaluations that critically influence stem cell regenerative medicine. Developing potency assays for cell-based medicinal products comes with numerous challenges due to the highly specialised nature of the application and purpose. This book provides the reader with the knowledge necessary to understand issues governing the successful development of potency assays, highlighting an international outlook of how the various challenges raised are being managed. Stakeholders concerned with potency assay development range from patient and clinician to contract research organisations, small and medium enterprise, regulatory authorities and even politicians. The value of potency assays is poised to increase given the inevitable watershed as early-stage clinical trials addressing safety progress to trials testing efficacy. Contributors from clinical, academic, industrial and regulatory sectors establish a broad point of view for guidance and timely debate. Potency assays require extensive collaboration across disciplines and sectors, as well as compromise and the authors aim to constructively address the many key aspects involved. Potency assays provide a quantitative measure of the biological activity of advanced therapy medicinal products (ATMPs) and thus are required for their market authorization. As the pace of ATMP development accelerates, the need to develop specific, accurate, and robust potency assays for each product is also accelerating. The volume Potency Assays for Stem Cell Advanced Therapy Medicinal Products presents a broad outlook on the development, quality attributes, and implementation of potency assays for ATMPs. The first few chapters introduce a nuanced historical perspective on the science of potency assay development, describe specific quality attributes of an idealized potency assay, indicate pitfalls associated with developing such assays for ATMPs, and review guidance recommended by regulatory authorities on assay suitability for product approval. Subsequent chapters highlight efforts to develop potency assays for specific ATMPs, including skeletal stem cells, mesenchymal stromal cells, extracellular vesicles, CAR T-cells, and discuss emerging technologies/platforms for potency assay design. The volume concludes with a chapter reviewing potency assays used for the release of commercial ATMP products, which amalgamates information contained in previous chapters. Overall, the knowledge contributed from leading authorities in both academia and industry is an ideal resource for technicians, scientists, clinicians, process engineers, and regulators working with ATMPs. —Donald G. Phinney, PhD Professor, Department of Molecular Medicine, Herbert Wertheim UF Scripps Institute for Biomedical Innovation & Technology

Vascular Dysfunction Beyond Pathological Pregnancies An International Effort Addressed to Fill the Gaps in Latin America Volume II

Vascular Dysfunction Beyond Pathological Pregnancies  An International Effort Addressed to Fill the Gaps in Latin America  Volume II
Author: Carlos Alonso Escudero,Fernanda Regina Giachini,Carlos Galaviz-Hernandez,Alicia E. Damiano
Publsiher: Frontiers Media SA
Total Pages: 242
Release: 2022-10-11
Genre: Science
ISBN: 9782832502082

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Public Health Matters Pandemic Policies Processes

Public Health Matters  Pandemic  Policies  Processes
Author: Noor Hazilah Abd Manaf,Yong Kang Cheah,Noor’ain Mohamad Yunus
Publsiher: Frontiers Media SA
Total Pages: 198
Release: 2022-05-27
Genre: Medical
ISBN: 9782889762514

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COVID 19 and the Law

COVID 19 and the Law
Author: I. Glenn Cohen,Abbe R. Gluck,Katherine Kraschel,Carmel Shachar
Publsiher: Cambridge University Press
Total Pages: 427
Release: 2023-10-31
Genre: Law
ISBN: 9781009265706

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This book examines the ethical, legal and regulatory impacts that COVID-19 has had on our society and institutions.