The Genome Generation

The Genome Generation
Author: Elizabeth Finkel
Publsiher: Melbourne Univ. Publishing
Total Pages: 290
Release: 2012
Genre: Science
ISBN: 9780522856477

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The year 2001 marked more than just the beginning of Stanley Kubrick's Space Odyssey, it marked the beginning of the genome era. That was the year scientists first read the 3 billion letters of DNA that make up the human genome. This was followed by a veritable Noah's Ark of genomesandmdash;sponges and worms, dogs and cows, rice and wheat, chimps and elephantsandmdash;180 creatures aboard so far. So what have we learned from all this? How has it changed the way we practise medicine, grow crops and breed livestock? What have we learned about evolution? These are the questions science writer and molecular biologist Elizabeth Finkel asked herself four years ago. To find the answers she travelled the science frontier from Botswana to Boston, from Warracknabeal to Mexico and tracked down scientists working in the field. Their stories, told here, paint the picture of what it means to be part of the genome generation. 'The Genome Generation is absolutely riveting. These tales from the frontier are a 'must read' for everyone who wishes to understand our pastandmdash;the logic of evolutionandmdash;or take a peep into our exciting future at the creation of 'super plants' through 'digital agriculture'.'andmdash;R.A. Mashelkar, CSIR Bhatnagar Fellow and India President, Global Research Alliance

Somatic Genome Variation

Somatic Genome Variation
Author: Xiu-Qing Li
Publsiher: John Wiley & Sons
Total Pages: 448
Release: 2017-04-20
Genre: Science
ISBN: 9781118647127

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Written by an international team of experts, Somatic Genome Variation presents a timely summary of the latest understanding of somatic genome development and variation in plants, animals, and microorganisms. Wide-ranging in coverage, the authors provide an updated view of somatic genomes and genetic theories while also offering interpretations of somatic genome variation. The text provides geneticists, bioinformaticians, biologist, plant scientists, crop scientists, and microbiologists with a valuable overview of this fascinating field of research.

Longevity Senescence and the Genome

Longevity  Senescence  and the Genome
Author: Caleb E. Finch
Publsiher: University of Chicago Press
Total Pages: 948
Release: 1994-05-16
Genre: Health & Fitness
ISBN: 0226248895

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Featuring extensive references, updated for this paperback edition, Longevity, Senescence, and the Genome constitutes a landmark contribution to biomedicine and the evolutionary biology of aging. To enhance gerontology's focus on human age-related dysfunctions, Caleb E. Finch provides a comparative review of all the phyla of organisms, broadening gerontology to intersect with behavioral, developmental, evolutionary, and molecular biology. By comparing species that have different developmental and life spans, Finch proposes an original typology of senescence from rapid to gradual to negligible, and he provides the first multiphyletic calculations of mortality rate constants.

Next Generation Genome Sequencing

Next Generation Genome Sequencing
Author: Michal Janitz
Publsiher: John Wiley & Sons
Total Pages: 282
Release: 2011-08-24
Genre: Science
ISBN: 9783527644735

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Written by leading experts from industry and academia, this first single comprehensive resource addresses recent developments in next generation DNA sequencing technology and their impact on genome research, drug discovery and health care. As such, it presents a detailed comparative analysis of commercially available platforms as well as insights into alternative, emerging sequencing techniques. In addition, the book not only covers the principles of DNA sequencing techniques but also social, ethical and commercial aspects, the concept of personalized medicine and a five-year perspective of DNA sequencing.

Rigor and Reproducibility in Genetics and Genomics

Rigor and Reproducibility in Genetics and Genomics
Author: Anonim
Publsiher: Academic Press
Total Pages: 504
Release: 2023-11-24
Genre: Medical
ISBN: 9780128172193

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Rigor and Reproducibility in Genetics and Genomics: Peer-reviewed, Published, Cited provides a full methodological and statistical overview for researchers, clinicians, students, and post-doctoral fellows conducting genetic and genomic research. Here, active geneticists, clinicians, and bioinformaticists offer practical solutions for a variety of challenges associated with several modern approaches in genetics and genomics, including genotyping, gene expression analysis, epigenetic analysis, GWAS, EWAS, genomic sequencing, and gene editing. Emphasis is placed on rigor and reproducibility throughout, with each section containing laboratory case-studies and classroom activities covering step-by-step protocols, best practices, and common pitfalls. Specific genetic and genomic technologies discussed include microarray analysis, DNA-seq, RNA-seq, Chip-Seq, methyl-seq, CRISPR gene editing, and CRISPR-based genetic analysis. Training exercises, supporting data, and in-depth discussions of rigor, reproducibility, and ethics in research together deliver a solid foundation in research standards for the next generation of genetic and genomic scientists. Provides practical approaches and step-by-step protocols to strengthen genetic and genomic research conducted in the laboratory or classroom Presents illustrative case studies and training exercises, discussing common pitfalls and solutions for genotyping, gene expression analysis, epigenetic analysis, GWAS, genomic sequencing, and gene editing, among other genetic and genomic approaches Examines best practices for microarray analysis, DNA-seq, RNA-seq, gene expression validation, Chip-Seq, methyl-seq, CRISPR gene editing, and CRISPR-based genetic analysis Written to provide trainees and educators with highly applicable tools and strategies to learn or refine a method toward identifying meaningful results with high confidence in their reproducibility

Plant Genetics and Molecular Biology

Plant Genetics and Molecular Biology
Author: Rajeev K. Varshney,Manish K. Pandey,Annapurna Chitikineni
Publsiher: Springer
Total Pages: 298
Release: 2018-09-04
Genre: Science
ISBN: 9783319913131

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This book reviews the latest advances in multiple fields of plant biotechnology and the opportunities that plant genetics, genomics and molecular biology have offered for agriculture improvement. Advanced technologies can dramatically enhance our capacity in understanding the molecular basis of traits and utilizing the available resources for accelerated development of high yielding, nutritious, input-use efficient and climate-smart crop varieties. In this book, readers will discover the significant advances in plant genetics, structural and functional genomics, trait and gene discovery, transcriptomics, proteomics, metabolomics, epigenomics, nanotechnology and analytical & decision support tools in breeding. This book appeals to researchers, academics and other stakeholders of global agriculture.

Genetic Transparency Ethical and Social Implications of Next Generation Human Genomics and Genetic Medicine

Genetic Transparency  Ethical and Social Implications of Next Generation Human Genomics and Genetic Medicine
Author: Malte Dreyer,Jeanette Erdmann,Christoph Rehmann-Sutter
Publsiher: BRILL
Total Pages: 292
Release: 2016-01-12
Genre: Social Science
ISBN: 9789004311893

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Genetic Transparency? tackles the question of who has, or should have access to personal genomic information. Genomics experts and scholars from the humanities and social sciences discuss the changes in interpersonal relationships, human self-understandings, ethics, law, and the health systems.

Evolution in Action Past Present and Future

Evolution in Action  Past  Present and Future
Author: Wolfgang Banzhaf,Betty H.C. Cheng,Kalyanmoy Deb,Kay E. Holekamp,Richard E. Lenski,Charles Ofria,Robert T. Pennock,William F. Punch,Danielle J. Whittaker
Publsiher: Springer Nature
Total Pages: 607
Release: 2020-07-08
Genre: Computers
ISBN: 9783030398316

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This edited research monograph brings together contributions from computer scientists, biologists, and engineers who are engaged with the study of evolution and how it may be applied to solve real-world problems. It also serves as a Festschrift dedicated to Erik D. Goodman, the founding director of the BEACON Center for the Study of Evolution in Action, a pioneering NSF Science and Technology Center headquartered at Michigan State University. The contributing authors are leading experts associated with the center, and they serve in top research and industrial establishments across the US and worldwide. Part I summarizes the history of the BEACON Center, with refreshingly personal chapters that describe Erik's working and leadership style, and others that discuss the development and successes of the center in the context of research funding, projects, and careers. The chapters in Part II deal with the evolution of genomes and evolvability. The contributions in Part III discuss the evolution of behavior and intelligence. Those in Part IV concentrate on the evolution of communities and collective dynamics. The chapters in Part V discuss selected evolutionary computing applications in domains such as arts and science, automated program repair, cybersecurity, mechatronics, and genomic prediction. Part VI deals with evolution in the classroom, using creativity in research, and responsible conduct in research training. The book concludes with a special chapter from Erik Goodman, a short biography that concentrates on his personal positive influences and experiences throughout his long career in academia and industry.