The Value of BCG and TNF in Autoimmunity

The Value of BCG and TNF in Autoimmunity
Author: Denise Faustman
Publsiher: Academic Press
Total Pages: 200
Release: 2018-08-01
Genre: Medical
ISBN: 9780081025901

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The Value of BCG and TNF in Autoimmune Diseases, Second Edition provides an overview on the current research related to TNF induction and the use of the BCG vaccine as a potential treatment approach to diverse forms of autoimmunity, allergies, infections and neurologic diseases. Since the initial conference (2013) and first edition of this book (2014), the field of BCG research has grown considerably. This new edition contains updates on MS and diabetes, and features at least eight additional chapters on new prevention and treatment trials in autoimmunity and allergy, along with a new understanding of the genetics of BCGs. Brings a different perspective on treatment approaches for certain autoimmune conditions Gives insight into the how the BCG vaccine impacts gene expression and the durability of the BCG vaccines in long lasting clinic effects Discusses TNF induction, rather than anti-TNF, as a therapeutic pathway for autoimmunity treatment Covers new topics, such as the Epigenetics of tuberculosis, BCG in neurological disease, BCG in early childhood and allergy, BCG in large prevention trials, Gene expression of BCG and re-methylation of genes, and more

Nutrition and Cardiovascular Health

Nutrition and Cardiovascular Health
Author: Paramjit S. Tappia,Heather Blewett
Publsiher: MDPI
Total Pages: 278
Release: 2020-06-17
Genre: Science
ISBN: 9783039288878

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There is unequivocal experimental, epidemiological, and clinical evidence demonstrating a correlation between diet and increased risk of cardiovascular disease (CVD). While nutritionally-poor diets can have a significant negative impact on cardiovascular health, dietary interventions with specific nutrients and/or functional foods are considered cost-effective and efficient components of prevention strategies. It has been estimated that nutritional factors may be responsible for approximately 40% of all CVD. Indeed, in one of the seminal studies conducted on modifiable risk factors and heart health (the INTERHEART study), >90% of all myocardial infarctions were attributed to preventable environmental factors with nutrition identified as one of the important determinants of CVD. There is an increasing public interest in and scientific investigation into establishing dietary approaches that can be undertaken for the prevention and treatment of CVD. This Special Issue provides an insight into the influential role of nutrition and dietary habits on cardiovascular health and disease, as well as their mechanisms of therapeutic and preventive action.

Heterologous Immunity Implications and Applications in Vaccines and Immunotherapies

Heterologous Immunity  Implications and Applications in Vaccines and Immunotherapies
Author: Babita Agrawal,Stephanie Yanow,Shakti Singh
Publsiher: Frontiers Media SA
Total Pages: 168
Release: 2020-08-27
Genre: Electronic Book
ISBN: 9782889639656

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Clinical Perspectives and Targeted Therapies in Apoptosis

Clinical Perspectives and Targeted Therapies in Apoptosis
Author: Rupinder K. Sodhi,Jitender Madan
Publsiher: Academic Press
Total Pages: 432
Release: 2020-10-15
Genre: Medical
ISBN: 9780128157633

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Clinical Perspectives and Targeted Therapies in Apoptosis: Drug Discovery, Drug Delivery, and Disease Prevention provides comprehensive coverage, from basic cell biology, to modern assessment techniques for apoptosis in all major disease areas. Chapters provide an introduction to the fundamentals of cell biology, biochemical mechanisms, and the pathophysiological consequences of apoptosis. In addition, the book covers the tools and techniques used to quantify apoptosis and the significance of apoptosis in drug discovery, drug delivery, and its applications in disease prevention. Finally, the book provides a comprehensive compilation of the apoptosis targeting drugs that recently underwent clinical trials. This combination of fundamentals, along with applications in drug discovery, drug delivery, and clinical research make this book a useful resource for those in both academia and industry who are engaged in pharmaceutical, biomedical and biotechnology research. Offers standard and innovative therapeutic approaches to modulate apoptosis in clinical interventions, such as cardiovascular diseases, immune disorders, cancer chemotherapy and neurological ailments Covers cutting-edge laboratory techniques and traditional protocols to determine apoptosis, both in vitro and in vivo Examines clinical study reports of new drug moieties that are explored for various pathological conditions associated with apoptosis

Immunotherapy of Type 1 Diabetes

Immunotherapy of Type 1 Diabetes
Author: Domenico Andreani,Hubert Kolb,Paolo Pozzilli
Publsiher: John Wiley & Sons
Total Pages: 280
Release: 1989
Genre: Diabetes
ISBN: UOM:39015015329371

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Recent national, European and international diabetes meetings have seen controversial discussions on the potential benefit and also on ethical aspects of immune intervention in patients with Type 1 diabetes or in persons with a high risk of developing the disease.

Vaccines and Autoimmunity

Vaccines and Autoimmunity
Author: Yehuda Shoenfeld,Nancy Agmon-Levin,Lucija Tomljenovic
Publsiher: John Wiley & Sons
Total Pages: 394
Release: 2015-07-07
Genre: Science
ISBN: 9781118663431

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In light of the discovery of Autoimmune Syndrome Induced by Adjuvants, or ASIA, Vaccines and Autoimmunity explores the role of adjuvants – specifically aluminum in different vaccines – and how they can induce diverse autoimmune clinical manifestations in genetically prone individuals. Vaccines and Autoimmunity is divided into three sections; the first contextualizes the role of adjuvants in the framework of autoimmunity, covering the mechanism of action of adjuvants, experimental models of adjuvant induced autoimmune diseases, infections as adjuvants, the Gulf War Syndrome, sick-building syndrome (SBS), safe vaccines, toll-like receptors, TLRS in vaccines, pesticides as adjuvants, oil as adjuvant, mercury, aluminum and autoimmunity. The following section reviews literature on vaccines that have induced autoimmune conditions such as MMR and HBV, among others. The final section covers diseases in which vaccines were known to be the solicitor – for instance, systemic lupus erythematosus – and whether it can be induced by vaccines for MMR, HBV, HCV, and others. Edited by leaders in the field, Vaccines and Autoimmunity is an invaluable resource for advanced students and researchers working in pathogenic and epidemiological studies.

Canadian Immunization Guide

Canadian Immunization Guide
Author: Canada. Comité consultatif national de l'immunisation,Canada. National Advisory Committee on Immunization
Publsiher: Unknown
Total Pages: 392
Release: 2006
Genre: Immunization
ISBN: 0660193922

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The seventh edition of the Canadian Immunization Guide was developed by the National Advisory Committee on Immunization (NACI), with the support ofthe Immunization and Respiratory Infections Division, Public Health Agency of Canada, to provide updated information and recommendations on the use of vaccines in Canada. The Public Health Agency of Canada conducted a survey in 2004, which confi rmed that the Canadian Immunization Guide is a very useful and reliable resource of information on immunization.

Essential Immunology for Surgeons

Essential Immunology for Surgeons
Author: Oleg Eremin,Herb Sewell
Publsiher: Oxford University Press
Total Pages: 547
Release: 2011-04-28
Genre: Medical
ISBN: 9780199586875

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Previously published as: The Immunological basis of surgical science and practice, 1992.