Viral

"Chan and Ridley write with an urgency...that inspires gripping depictions of what viruses are, how infectious-disease laboratories work and wonderfully lucid descriptions of bats. . . . They powerfully recount how dangerous pathogens can both leak from a lab and emerge in nature." (New York Times Book Review) Understanding how Covid-19 started is crucial for the future of humankind. Viral is the most incisive and authoritative book about the search for the source of the virus. A new virus descended on the human species in 2019 wreaking unprecedented havoc. Finding out where it came from and how it first jumped into people is an urgent priority, but early expectations that this would prove an easy question to answer have been dashed. Nearly two years into the pandemic, the crucial mystery of the origin of SARS-CoV-2 is not only unresolved but has deepened. In this uniquely insightful book, a scientist and a writer join forces to try to get to the bottom of how a virus whose closest relations live in bats in subtropical southern China somehow managed to begin spreading among people more than 1,500 kilometres away in the city of Wuhan. They grapple with the baffling fact that the virus left none of the expected traces that such outbreaks usually create: no infected market animals or wildlife, no chains of early cases in travellers to the city, no smouldering epidemic in a rural area, no rapid adaptation of the virus to its new host—human beings. To try to solve this pressing mystery, Viral delves deep into the events of 2019 leading up to 2021, the details of what went on in animal markets and virology laboratories, the records and data hidden from sight within archived Chinese theses and websites, and the clues that can be coaxed from the very text of the virus’s own genetic code. The result is a gripping detective story that takes the reader deeper and deeper into a metaphorical cave of mystery. One by one the authors explore promising tunnels only to show that they are blind alleys, until, miles beneath the surface, they find themselves tantalisingly close to a shaft that leads to the light.

So far, twenty-three thousand and ninety-six people have seen me online. Su has always been the successful sister. It's Leah who is wild and often angry. But when they go to Magaluf to celebrate their exam results, Su disappears. Su is on the run, humiliated and afraid. There's an online video of her performing multiple sex acts in a nightclub. And everyone has seen it. Their mother Ruth, a prominent court judge, is furious. Can she bring justice to the men who took advantage of her daughter, and what will it take to bring Su home? 'Read it.' Stylist 'Gripping.' Tammy Cohen, author of When She Was Bad 'A real psychological roller-coaster.' Scotsman

In this electrifying medical thriller from New York Times bestselling author Robin Cook, a family’s exposure to a rare yet deadly virus ensnares them in a growing danger to mankind—and pulls back the curtain on a healthcare system powered by profit and greed. Trying to find some normalcy during the Covid-19 pandemic, Brian Murphy and his family are on a summer excursion in Cape Cod when his wife, Emma, comes down with concerning flu-like symptoms. But their leisurely return home to New York City quickly becomes a race to the local hospital as she suddenly begins seizing in the car. At the ICU, she is diagnosed with eastern equine encephalitis, a rare and highly lethal mosquito-borne viral disease seemingly caught during one of their evening cookouts. Complicating the situation further, Brian and Emma’s young daughter then begins to exhibit alarming physical and behavioral symptoms, too. Emma’s harrowing hospital stay turns even more fraught when Brian receives a staggering hospital bill full of outrageous charges and murky language. To add insult to injury, his health insurance company refuses to cover any of the cost, citing dubious clauses in Brian’s policy. Forced to choose between the ongoing care of family and bills he can never pay, and furious at a shockingly indifferent healthcare system, Brian vows to seek justice. But to get to the bottom of the predatory practices targeting his loved ones and countless others, he must uncover the dark side of an industry that has strayed drastically from its altruistic roots—and bring down the callous executives preying on the sick and defenseless before the virus can claim even more people . . .

Using a multidisciplinary approach, Human Respiratory Viral Infections is set at the level between the definitive reference work and an essential clinical manual. Exploring recent advances in human respiratory viral research, the text builds on the basic sciences of epidemiology, virology, molecular biology, and immunology to cover clinical diagnos

The 4th edition of Viral Hepatitis coverscomprehensively the entire complex field of infections caused byall of the different hepatitis viruses, which affect many millionsof people throughout the world with considerable morbidity andmortality. Howard Thomas and Arie Zuckerman are joined by Anna Lok from theUSA and Stephen Locarnini from Australia as Editors. Theyhave recruited leading researchers and physicians from manycountries, who have produced an authoritative account of currentknowledge and research on this important infection, including newinsights into immune response to HBV and HCV. The result is a comprehensive account on all aspects of viralhepatitis, including rapid advances in the diagnosis, management,treatment and prevention of a complex infection, which in the caseof hepatitis B, C and D may lead to severe complications includingchronic hepatitis, cirrhosis and hepatocellular carcinoma. The latest edition of Viral Hepatitis offers an essentialresource of current information for hepatologists,gastroenterologists, infectious diseases specialists and otherclinicians, researchers, public health physicians and National andInternational Health Authorities.

With further rapid advances in diagnosis and therapy, the field of chronic viral hepatitis C and B has changed in important ways since the first edition of this best-selling text. This new edition is intended to bring all those involved in the care of patients with hepatitis up to date with the latest management guidelines. To help the reader, clear diagnostic algorithms are provided, along with MCQs at the end of each chapter for self-testing

The pregnant host is at risk for any of the viral diseases her nonpregnant counterpart acquires. Additionally, pregnancy heightens our concerns regarding specific viral diseases be cause of their potential for enhanced adverse effects on both maternal and fetal well-being. All too often the obstetrician relinquishes responsibility for the management of the gravida infected by a viral pathogen, and those expert in infectious diseases are confounded by the influence of pregnancy on these conditions. A major goal of this textbook is to narrow the gap between the two aforementioned management dichotomies in the virally infected pregnant woman. Weare at the infancy of our understanding of viral infections in pregnancy. The current and anticipated advancements are due in large part to a burgeoning oftechnological achievements in the areas of immunodiagnostics, molecular biology, and pharmacotherapeutics. Our in utero diagnostic capabilities, both invasive and noninvasive, have also allowed us new opportunities to study the effects of various maternal infectious disease processes on the developing fetus. New insights have been recognized pertaining to the maternal-fetal interface, the placenta, in that this structure is now acknowledged to function as both a mechanical and an immunological barrier to vertical transmission of infection. These observations suggest that there will be an outpouring of new data in the next several years that clinicians will need to master to maintain an appropriate level of expertise in the care of their patients.

In Going Viral, Nahon and Hemsley uncover the factors that make things go viral online. They analyze the characteristics of networks that shape virality, including the crucial role of gatekeepers who control the flow of information and connect networks to one another. They also explore the role of human attention, showing how phenomena like word of mouth, bandwagon effects, homophily and interest networks help to explain the patterns of individual behavior that make viral events.