Advanced Materials For Biomedical Applications

This book provides an insight into the basic fundamentals of the biomaterials used for the biomedical applications, their development and processing techniques. Advanced materials are significantly utilized for the biomedical applications ranging from dental devices to cancer treatment owing to their higher biocompatibility and better interaction with tissues. This book covers the various topics that include basic biocompatibility phenomena, insight to materials science, class of different advanced materials as a biomaterials, development and processing techniques, design and analysis of the developed advanced materials, investigation of its properties and major applications. Recent information regarding the development techniques and methods for improving the properties of the advanced materials in the field of biomedical applications is highlighted in detail. The textbook offers clear explanation of the text in the chapters with self-explanatory figures and tables. It demonstrates the novel methods, opportunities and ideas for developing biomaterials in the field of biomedical applications. It also includes critical review study of the developed advanced materials for biomedical applications in a new summarized form. The inclusion of the discussions on hybrid polymer-based composites and self-healing composite materials offers a special feature in the textbook. It features a thorough overview of the simulation aspect in the biomedical applications. The book features at least 50% of its references from last three–four years’ work in the field of biomaterials and biomedical. The book content adds to the redundancy in the literature work related to biomedical and biomaterials. This book is a valuable resource for academicians, students and scholars from science and engineering background having interest in biomaterials. It is helpful to the biomedical engineering group especially in countries or location where they don’t have access to the major journals.

The text discusses synthesis, processing, design, simulation and characterization of biomaterials for biomedical applications. It synergizes exploration related to various properties and functionalities in the biomedical field through extensive theoretical and experimental modeling. It further presents advanced integrated design and nonlinear simulation problems occurring in the biomedical engineering field. It will serve as an ideal reference text for senior undergraduate and graduate students, and academic researchers in fields including biomedical engineering, mechanical engineering, materials science, ergonomics, and human factors. The book: Employs a problem-solution approach, where, in each chapter, a specific biomedical engineering problem is raised and its numerical, and experimental solutions are presented Covers recent developments in biomaterials such as OPMF/KGG bio composites, PEEK-based biomaterials, PF/KGG biocomposites, oil palm mesocarp Fibre/KGG biocomposites, and polymeric resorbable materials for orthopedic, dentistry and shoulder arthroplasty applications Discusses mechanical performance and corrosive analysis of biomaterials for biomedical applications in detail Presents advanced integrated design and nonlinear simulation problems occurring in the biomedical engineering field Presents biodegradable polymers for various biomedical applications over the last decade owing to their non-corrosion in the body, biocompatibility and superior strength in growing state Synergizes exploration related to the various properties and functionalities in the biomedical field through extensive theoretical and experimental modeling

ADVANCED MATERIALS and MANUFACTURING TECHNIQUES for BIOMEDICAL APPLICATIONS The book provides essential knowledge for the synthesis of biomedical products, development, nanomaterial properties, fabrication processes, and design techniques for different applications, as well as process design and optimization. In origin, biomaterials can come from nature or be synthesized in the laboratory with a variety of approaches that use metals, polymers, ceramic, or composite materials. They are often used or adapted for various biomedical applications. Biomaterials are commonly used in scaffolds, orthopedic, wound healing, fracture fixation, surgical sutures, artificial organ developments, pins and screws to stabilize fractures, surgical mesh, breast implants, artificial ligaments and tendons, and drug delivery systems. The sixteen chapters in Advanced Materials and Manufacturing Techniques in Biomedical Applications cover the synthesis, processing, design, manufacturing, and characterization of advanced materials; self-healing, bioinspired, nature-resourced, nanobiomaterials for biomedical applications; and manufacturing techniques such as rapid prototyping, additive manufacturing, etc. Audience The book is for engineers, technologists, and researchers working in the area of biomedical engineering and manufacturing techniques. It is also appropriate for upper-level undergraduate and graduate students.

Offers a comprehensive and interdisciplinary view of cutting-edge research on advanced materials for healthcare technology and applications Advanced healthcare materials are attracting strong interest in fundamental as well as applied medical science and technology. This book summarizes the current state of knowledge in the field of advanced materials for functional therapeutics, point-of-care diagnostics, translational materials, and up-and-coming bioengineering devices. Advanced Healthcare Materials highlights the key features that enable the design of stimuli-responsive smart nanoparticles, novel biomaterials, and nano/micro devices for either diagnosis or therapy, or both, called theranostics. It also presents the latest advancements in healthcare materials and medical technology. The senior researchers from global knowledge centers have written topics including: State-of-the-art of biomaterials for human health Micro- and nanoparticles and their application in biosensors The role of immunoassays Stimuli-responsive smart nanoparticles Diagnosis and treatment of cancer Advanced materials for biomedical application and drug delivery Nanoparticles for diagnosis and/or treatment of Alzheimers disease Hierarchical modelling of elastic behavior of human dental tissue Biodegradable porous hydrogels Hydrogels in tissue engineering, drug delivery, and wound care Modified natural zeolites Supramolecular hydrogels based on cyclodextrin poly(pseudo)rotaxane Polyhydroxyalkanoate-based biomaterials Biomimetic molecularly imprinted polymers

This book provides in-depth knowledge about cross rolling of biomedical alloys, cellulose, magnetic iron oxide nanoparticles, magnesium-based nanocomposites, titanium, titanium alloys, stainless steel, and improved biodegradable implants materials for biomechanical applications like joint replacements, bone plates, bone cement, artificial ligaments and tendons, dental implants for tooth fixation, and hip implants. It comprehensively covers advancements in materials including graphene-reinforced magnesium metal matrix, magnesium and its alloys, and 2D nanomaterials. The text discusses important topics including advanced materials for biomechanical applications, design, and analysis of stainless steel 316L for femur bone fracture healing, design and manufacturing of prosthetic dental implants, a biomechanical study of a low-cost prosthetic leg, and an energy harvesting mechanism for walking applications. The text will serve as a useful text for graduate students, academic researchers, and general practitioners in areas including materials science, manufacturing engineering, mechanical engineering, and biomechanical engineering.

This book highlights recent advances in the field of biomaterials design and the state of the art in biomaterials applications for biomedicine. Addressing key aspects of biomaterials, the book explores technological advances at multi-scale levels (macro, micro, and nano), which are used in applications related to cell and tissue regeneration. The book also discusses the future scope of bio-integrated systems. The contents are supplemented by illustrated examples, and schematics of molecular and cellular interactions with biomaterials/scaffolds are included to promote a better understanding of the complex biological mechanisms involved in material-to-biomolecule interactions. The book also covers factors that govern cell growth, differentiation, and regeneration in connection with the treatment and recovery of native biological systems. Tissue engineering, drug screening and delivery, and electrolyte complexes for biomedical applications are also covered in detail. This book offers a comprehensive reference guide for multi-disciplinary communities working in the area of biomaterials, and will benefit researchers and graduate students alike.

Dynamic soft materials that have the ability to expand and contract, change stiffness, self-heal or dissolve in response to environmental changes, are of great interest in applications ranging from biosensing and drug delivery to soft robotics and tissue engineering. This book covers the state-of-the-art and current trends in the very active and exciting field of bioinspired soft matter, its fundamentals and comprehension from the structural-property point of view, as well as materials and cutting-edge technologies that enable their design, fabrication, advanced characterization and underpin their biomedical applications. The book contents are supported by illustrated examples, schemes, and figures, offering a comprehensive and thorough overview of key aspects of soft matter. The book will provide a trusted resource for undergraduate and graduate students and will extensively benefit researchers and professionals working across the fields of chemistry, biochemistry, polymer chemistry, materials science and engineering, nanosciences, nanotechnologies, nanomedicine, biomedical engineering and medical sciences.