An Introduction To Hplc For Pharmaceutical Analysis
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An Introduction to HPLC for Pharmaceutical Analysis
Author | : Oona McPolin |
Publsiher | : Lulu.com |
Total Pages | : 150 |
Release | : 2009-03-01 |
Genre | : Medical |
ISBN | : 9780956152800 |
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If you are new to HPLC, this book provides an invaluable guide to how HPLC is actually used when analysing pharmaceuticals. It is full of practical advice on the operation of HPLC systems combined with the necessary theoretical knowledge to ensure understanding of the technique. Key features include: A thorough discussion of the stationary phase enabling the reader to make sense of the many parameters used to describe a HPLC column; Practical advice and helpful hints for the preparation and use of mobile phase; A complete overview of each of the different components which together make up a HPLC system; A description of the contents of a typical HPLC analytical method and how to interpret these; A step-by-step guide on how to follow a method and set up a HPLC analysis; A discussion of system suitability criteria and how to interpret the values obtained during an analysis; Explanation of the common methods of calibration and quantification used for pharmaceutical analysis.
Handbook of Pharmaceutical Analysis by HPLC
Author | : Satinder Ahuja,Michael Dong |
Publsiher | : Elsevier |
Total Pages | : 679 |
Release | : 2005-02-09 |
Genre | : Medical |
ISBN | : 9780080455181 |
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High pressure liquid chromatography–frequently called high performance liquid chromatography (HPLC or, LC) is the premier analytical technique in pharmaceutical analysis and is predominantly used in the pharmaceutical industry. Written by selected experts in their respective fields, the Handbook of Pharmaceutical Analysis by HPLC Volume 6, provides a complete yet concise reference guide for utilizing the versatility of HPLC in drug development and quality control. Highlighting novel approaches in HPLC and the latest developments in hyphenated techniques, the book captures the essence of major pharmaceutical applications (assays, stability testing, impurity testing, dissolution testing, cleaning validation, high-throughput screening). A complete reference guide to HPLC Describes best practices in HPLC and offers 'tricks of the trade' in HPLC operation and method development Reviews key HPLC pharmaceutical applications and highlights currents trends in HPLC ancillary techniques, sample preparations, and data handling
HPLC for Pharmaceutical Scientists
Author | : Yuri V. Kazakevich,Rosario LoBrutto |
Publsiher | : John Wiley & Sons |
Total Pages | : 1136 |
Release | : 2007-02-16 |
Genre | : Science |
ISBN | : 9780470087947 |
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HPLC for Pharmaceutical Scientists is an excellent book for both novice and experienced pharmaceutical chemists who regularly use HPLC as an analytical tool to solve challenging problems in the pharmaceutical industry. It provides a unified approach to HPLC with an equal and balanced treatment of the theory and practice of HPLC in the pharmaceutical industry. In-depth discussion of retention processes, modern HPLC separation theory, properties of stationary phases and columns are well blended with the practical aspects of fast and effective method development and method validation. Practical and pragmatic approaches and actual examples of effective development of selective and rugged HPLC methods from a physico-chemical point of view are provided. This book elucidates the role of HPLC throughout the entire drug development process from drug candidate inception to marketed drug product and gives detailed specifics of HPLC application in each stage of drug development. The latest advancements and trends in hyphenated and specialized HPLC techniques (LC-MS, LC-NMR, Preparative HPLC, High temperature HPLC, high pressure liquid chromatography) are also discussed.
HPLC Methods for Pharmaceutical Analysis Volumes 2 4
Author | : George Lunn |
Publsiher | : Wiley-Interscience |
Total Pages | : 0 |
Release | : 2000-01-21 |
Genre | : Science |
ISBN | : 0471332968 |
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The most commonly used method for analyzing substances, and the first method most researchers turn to, is high performance liquid chromatography (HPLC). Following up on a best-seller, volumes 2-4 continue to provide an easily-accessible collection of procedures for analyzing pharmaceuticals using HPLC.
HPLC in the Pharmaceutical Industry
Author | : Godwin W. Fong |
Publsiher | : CRC Press |
Total Pages | : 332 |
Release | : 1991-03-14 |
Genre | : Science |
ISBN | : 0824784995 |
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A practical guide for chemists in the pharmaceutical industry to making automated analyses of drugs that will meet the standards of regulatory agencies. Reviews the standard techniques of high-performance liquid chromatography, specialized detection methods, automation in pharmaceutical analysis, an
HPLC Methods for Pharmaceutical Analysis
Author | : George Lunn,Norman R. Schmuff |
Publsiher | : Wiley-Interscience |
Total Pages | : 2370 |
Release | : 1997 |
Genre | : Science |
ISBN | : STANFORD:36105111547712 |
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Full text included in Knovel Library within the subject area of Chemistry and Chemical Engineering.
High Performance Liquid Chromatography
Author | : W.J. Lough,I.W. Wainer |
Publsiher | : CRC Press |
Total Pages | : 292 |
Release | : 1995-09-30 |
Genre | : Science |
ISBN | : 0751400769 |
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High performance liquid chromatography (HPLC) has long been recognized as one of the most useful and versatile analytical techniques. It has now progressed from being a highly expensive method of analysis to a routine technique with wide applications. Consequently there is a requirement in many chemistry and chemistry-related courses for students to acquire a detailed understanding of the principles and practice of HPLC. Written in a manner suitable for undergraduate students studying analytical chemistry and learning about chromatographic analytical techniques applied to pharmaceutical analysis, biochemistry and related disciplines, High-performance Liquid Chromatography: Fundamental Principles and Practice introduces the fundamentals of HPLC. Loosely structured in three parts, the text begins with a thorough introduction of the subject and then progresses through the essential knowledge of the instrumentation needed for HPLC. The final part covers with the applications of HPLC in real-world situations. Developed by a team of international experts from a wide cross-section of disciplines, the text is relevant to a wide range of courses.
HPLC Method Development for Pharmaceuticals
Author | : Satinder Ahuja,Henrik Rasmussen |
Publsiher | : Elsevier |
Total Pages | : 532 |
Release | : 2011-09-21 |
Genre | : Medical |
ISBN | : 9780080554198 |
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High pressure, or high performance, liquid chromatography (HPLC) is the method of choice for checking purity of new drug candidates, monitoring changes during scale up or revision of synthetic procedures, evaluating new formulations, and running control/assurance of the final drug product. HPLC Method Development for Pharmaceuticals provides an extensive overview of modern HPLC method development that addresses these unique concerns. Includes a review and update of the current state of the art and science of HPLC, including theory, modes of HPLC, column chemistry, retention mechanisms, chiral separations, modern instrumentation (including ultrahigh-pressure systems), and sample preparation. Emphasis has been placed on implementation in a pharmaceutical setting and on providing a practical perspective. HPLC Method Development for Pharmaceuticals is intended to be particularly useful for both novice and experienced HPLC method development chemists in the pharmaceutical industry and for managers who are seeking to update their knowledge. Covers the requirements for HPLC in a pharmaceutical setting including strategies for software and hardware validation to allow for use in a regulated laboratory Provides an overview of the pharmaceutical development process (clinical phases, chemical and pharmaceutical development activities) Discusses how HPLC is used in each phase of pharmaceutical development and how methods are developed to support activities in each phase