An Introduction To Pain And Its Relation To Nervous System Disorders

Introduction to Pain and its relation to Nervous System Disorders provides an accessible overview of the latest developments in the science underpinning pain research, including, but not limited to, the physiological, pathological and psychological aspects. This unique book fills a gap in current literature by focussing on the intricate relationship between pain and human nervous system disorders such as Autism, Alzheimer Disease, Parkinson’s Disease, Depression and Multiple Sclerosis. This fully illustrated, colour handbook will help non-experts, including advanced undergraduate and new postgraduate students, become familiar with the current, wide-ranging areas of research that cover every aspect of the field from chronic and inflammatory pain to neuropathic pain and biopsychosocial models of pain, functional imaging and genetics. Contributions from leading experts in neuroscience and psychiatry provide both factual information and critical points of view on their approach and the theoretical framework behind their choices. An appreciation of the strengths and weaknesses of brain imaging technology applied to pain research in humans provides the tools required to understand current cutting edge literature on the topic. Chapters covering placebo effects in analgesia and the psychology of pain give a thorough overview of cognitive, psychological and social influences on pain perception. Sections exploring pain in the lifecycle and in relation to nervous system disorders take particular relevance from a clinical point of view. Furthermore, an intellectually stimulating chapter analysing the co-morbidity of pain and depression provides a philosophical angle rarely presented in related handbooks. The references to external research databases and relevant websites aim to prompt readers to become critical and independent thinkers, and motivate them to carry out further reading on these topics. Introduction to Pain and its relation to Nervous System Disorders is essential reading for advanced undergraduate and postgraduate students in neuroscience, medical and biomedical sciences, as well as for clinical and medical healthcare professionals involved in pain management.

This volume provides a comprehensive accounting of pain and its relation to neurology. It is dedicated entirely to the mechanisms and clinical aspects of the subject, and provides a wealth of information on the latest neurobiological and clinical data surrounding the topic. From discussions of the physiology and pathology of the pain pathways from signaling, via spinal cord and supraspinal processing to endogenous pain modulation, users will gain an invaluable reference that provides a new understanding of pain related topics, including cytokines, sex differences, and the autonomic nervous system. Practicing clinicians, internists, surgeons, and those in the fields of psychiatry and gerontology will gain a greater understanding of this challenging topic with chapters that deal extensively with peripheral and central pain conditions, including specific disorders such as fibromyalgia, whiplash, psychiatric diseases, dementia, and even cancer. In addition, treatments for neuropathic pain are also thoroughly presented and discussed. * A comprehensive guide to the topic of pain and its relation to neurology* Invaluable information on specific topics of interest, including discussions of pain and its implications for related diseases and conditions such as fibromyalgia, whiplash, and even psychiatric disorders* Treatment protocols for neuropathic pain and patient care

Pain Syndromes in Neurology deals with the diagnosis and treatment of painful conditions associated with dysfunction of the peripheral or central nervous system. It discusses advances in three areas: first, the normal anatomy and physiology of pain; second, the pathophysiology of damaged sensory neurons; and third, the diagnosis and treatment of patients with neuropathic pain. The book begins with a discussion of neural mechanisms relevant to pain perception along with a brief review of neuropathic pain. This is followed by separate chapters on hyperalgesia following cutaneous injury; the importance of peripheral processes in the etiology of neuropathic and radiculopathic pain; and mechanisms by which sympathetic efferent fibers contribute to the occurrence of pain. Subsequent chapters cover the diagnosis and treatment of reflex sympathetic dystrophy; pain in generalized neuropathies; surgical treatment of pain; clinical features and management of postherpetic neuralgia; diagnosis of cancer pain syndromes; and drugs in the management of chronic pain.

Many patients suffer from problems in their muscles or nerves in combination with pain. This book is about the complex interplay between the causes of these problems and the puzzle they pose. Pain is the subjective experience of a psychophysical phenomenon arising from a defined area in the body. It is a cry for help and challenges the physician to ask the right questions and to carry out the right examinations. If they succeed in doing so, the patient’s signs and symptoms will be translated into the present knowledge of pain concepts to initiate appropriate therapy. With this goal in mind, this book summarizes the latest scientific information on pain states and their mechanisms. It provides a deeper understanding of the different pain conditions and allows physicians to form strategies for better pain therapy. The second edition includes more graphs, tables, and illustrations. It is updated with the current and dynamically expanding knowledge on the therapy of several disease states and explains in more detail the processing of pain in the central nervous system. When puzzling symptoms of sensory, motor, and autonomic deficits are evident, an examination has to be performed systematically in order to reach the correct diagnosis. This calls for suitable anatomical knowledge. Depending on where a lesion exists within a peripheral nerve, the root or the plexus, typical patterns of paralysis can be detected. Numerous illustrations in the book help physicians to more easily understand and solve problems of peripheral nerve and root injuries and their sequelae in their daily work.

It is only natural for someone in pain to attend to the body part that hurts. Yet this book tells the story of persistent pain having negative effects on brain function. The contributors, all leading experts in their respective fields of pain electrophysiology, brain imaging, and animal models of pain, strive to synthesize compelling and, in some ways, connected hypotheses with regard to pain-related changes in the brain. Together, they contribute their clinical, academic, and theoretical expertise in a comprehensive overview that attempts to define the broader philosophical context of pain (disentangling sensical from nonsensical claims), list the changes known to take place in the brains of individuals with chronic pain and animal models of pain, address the possible causes and mechanisms underlying these changes, and detail the techniques and analytical methods at our disposal to "visualize" and study these changes. Philosophical and social concepts of pain; testimonials of chronic-pain patients Clinical data from pain patients’ brains Advances in noninvasive brain imaging for pain patients Combining theoretical and empirical approaches to the analysis of pain-related brain function Manipulation of brain function in animal models Emerging neurotechnology principles for pain diagnostics and therapeutics

This book challenges some long-held beliefs, models of treatment, and clinical reasoning about pain. It presents the current evidence on whatwe know about the sympathetic nervous system and the implications it has for patients with complex regional pain syndromes. Part 1 tackles controversial issues surrounding the role of the sympathetic nervous system in pain states and explores clinical challenges and questions that surround the topic. Can visceral disease precipitate musculoskeletal disorder? What do we know about mind body pathways? Where does the immune system fit in? What is complex regional pain syndrome? What is sympathetic maintained pain? How is it managed and treated? What are sympathetic blocks? Do they work? What happens to tissues when they are immobilised or under-used? What role does the sympathetic nervous system play in oedema, ischaemia and supersensitivity development? How can it cause pain? Part 2 is devoted to pain management. A single and highly authoritative chapter provides the information and clinical tools for us to deal more effectively with the distress and anger shown by some patients with back pain. There are excellent guidelines for clinicians seeking to further their 'Yellow Flag' assessment and management skills Part 3 addresses clinical effectiveness. It introduces, explains and discusses the concept and provides a rich resource for further research and investigation of the topic. There is also a critical look at 'evidence' and research into the effectiveness of acupuncture and TENS to help our understanding of the systematic review process and the pitfalls that so often occur in clinical research. The Topical Issues in Pain series derives from the work, study days and seminars of the Physiotherapy Pain Association and is written by clinicians for clinicians. Each volume reviews the literature and presents best practice in a lively and understandable text. All clinicians will benefit from the straightforward advice.

The decade since the publication of David Butler's Mobilisation of the Nervous System has seen the rapid growth and influence of the powerful and linked forces of the neurobiological revolution, the evidence based movements, restless patients and clinicians. The Sensitive Nervous System calls for skilled combined physical and educational contributions to the management of acute and chronic pain states. It offers a "big picture" approach using best evidence from basic sciences and outcomes data, with plenty of space for individual clinical expertise and wisdom.

Introduction to Pain and its relation to Nervous System Disorders provides an accessible overview of the latest developments in the science underpinning pain research, including, but not limited to, the physiological, pathological and psychological aspects. This unique book fills a gap in current literature by focussing on the intricate relationship between pain and human nervous system disorders such as Autism, Alzheimer Disease, Parkinson’s Disease, Depression and Multiple Sclerosis. This fully illustrated, colour handbook will help non-experts, including advanced undergraduate and new postgraduate students, become familiar with the current, wide-ranging areas of research that cover every aspect of the field from chronic and inflammatory pain to neuropathic pain and biopsychosocial models of pain, functional imaging and genetics. Contributions from leading experts in neuroscience and psychiatry provide both factual information and critical points of view on their approach and the theoretical framework behind their choices. An appreciation of the strengths and weaknesses of brain imaging technology applied to pain research in humans provides the tools required to understand current cutting edge literature on the topic. Chapters covering placebo effects in analgesia and the psychology of pain give a thorough overview of cognitive, psychological and social influences on pain perception. Sections exploring pain in the lifecycle and in relation to nervous system disorders take particular relevance from a clinical point of view. Furthermore, an intellectually stimulating chapter analysing the co-morbidity of pain and depression provides a philosophical angle rarely presented in related handbooks. The references to external research databases and relevant websites aim to prompt readers to become critical and independent thinkers, and motivate them to carry out further reading on these topics. Introduction to Pain and its relation to Nervous System Disorders is essential reading for advanced undergraduate and postgraduate students in neuroscience, medical and biomedical sciences, as well as for clinical and medical healthcare professionals involved in pain management.