Analysis And Control Of Complex Nonlinear Processes In Physics Chemistry And Biology

Nonlinear dynamics of complex processes is an active research field with large numbers of publications in basic research, and broad applications from diverse fields of science. Nonlinear dynamics as manifested by deterministic and stochastic evolution models of complex behavior has entered statistical physics, physical chemistry, biophysics, geophysics, astrophysics, theoretical ecology, semiconductor physics and -optics, etc. This field of research has induced a new terminology in science connected with new questions, problems, solutions and methods. New scenarios have emerged for spatio-temporal structures in dynamical systems far from equilibrium. Their analysis and possible control are intriguing and challenging aspects of the current research. The duality of fundamental and applied research is a focal point of its main attractivity and fascination. Basic topics and foundations are always linked to concrete and precise examples. Models and measurements of complex nonlinear processes evoke and provoke new fundamental questions that diversify and broaden the mathematical concepts and tools. In return, new mathematical approaches to modeling and analysis enlarge the scope and efficiency of applied research.

Nonlinear dynamics of complex processes is an active research field with large numbers of publications in basic research, and broad applications from diverse fields of science. Nonlinear dynamics as manifested by deterministic and stochastic evolution models of complex behavior has entered statistical physics, physical chemistry, biophysics, geophysics, astrophysics, theoretical ecology, semiconductor physics and -optics, etc. This field of research has induced a new terminology in science connected with new questions, problems, solutions and methods. New scenarios have emerged for spatio-temporal structures in dynamical systems far from equilibrium. Their analysis and possible control are intriguing and challenging aspects of the current research.The duality of fundamental and applied research is a focal point of its main attractivity and fascination. Basic topics and foundations are always linked to concrete and precise examples. Models and measurements of complex nonlinear processes evoke and provoke new fundamental questions that diversify and broaden the mathematical concepts and tools. In return, new mathematical approaches to modeling and analysis enlarge the scope and efficiency of applied research.

This research addresses delay effects in nonlinear systems, which are ubiquitous in various fields of physics, chemistry, biology, engineering, and even in social and economic systems. They may arise as a result of processing times or due to the finite propagation speed of information between the constituents of a complex system. Time delay has two complementary, counterintuitive and almost contradictory facets. On the one hand, delay is able to induce instabilities, bifurcations of periodic and more complicated orbits, multi-stability and chaotic motion. On the other hand, it can suppress instabilities, stabilize unstable stationary or periodic states and may control complex chaotic dynamics. This thesis deals with both aspects, and presents novel fundamental results on the controllability of nonlinear dynamics by time-delayed feedback, as well as applications to lasers, hybrid-mechanical systems, and coupled neural systems.

By establishing an alternative foundation of control theory, this thesis represents a significant advance in the theory of control systems, of interest to a broad range of scientists and engineers. While common control strategies for dynamical systems center on the system state as the object to be controlled, the approach developed here focuses on the state trajectory. The concept of precisely realizable trajectories identifies those trajectories that can be accurately achieved by applying appropriate control signals. The resulting simple expressions for the control signal lend themselves to immediate application in science and technology. The approach permits the generalization of many well-known results from the control theory of linear systems, e.g. the Kalman rank condition to nonlinear systems. The relationship between controllability, optimal control and trajectory tracking are clarified. Furthermore, the existence of linear structures underlying nonlinear optimal control is revealed, enabling the derivation of exact analytical solutions to an entire class of nonlinear optimal trajectory tracking problems. The clear and self-contained presentation focuses on a general and mathematically rigorous analysis of controlled dynamical systems. The concepts developed are visualized with the help of particular dynamical systems motivated by physics and chemistry.

Networked systems are all around us. The accumulated evidence of systems as complex as a cell cannot be fully understood by studying only their isolated constituents, giving rise to a new area of interest in research OCo the study of complex networks . In a broad sense, biological networks have been one of the most studied networks, and the field has benefited from many important contributions. By understanding and modeling the structure of a biological network, a better perception of its dynamical and functional behavior is to be expected. This unique book compiles the most relevant results and novel insights provided by network theory in the biological sciences, ranging from the structure and dynamics of the brain to cellular and protein networks and to population-level biology. Sample Chapter(s). Chapter 1: Introduction (61 KB). Contents: Networks at the Cellular Level: The Structural Network Properties of Biological Systems (M Brilli & P Li); Dynamics of Multicellular Synthetic Gene Networks (E Ullner et al.); Boolean Networks in Inference and Dynamic Modeling of Biological Systems at the Molecular and Physiological Level (J Thakar & R Albert); Complexity of Boolean Dynamics in Simple Models of Signaling Networks and in Real Genetic Networks (A D az-Guilera & R ulvarez-Buylla); Geometry and Topology of Folding Landscapes (L Bongini & L Casetti); Elastic Network Models for Biomolecular Dynamics: Theory and Application to Membrane Proteins and Viruses (T R Lezon et al.); Metabolic Networks (M C Palumbo et al.); Brain Networks: The Human Brain Network (O Sporns); Brain Network Analysis from High-Resolution EEG Signals (F De Vico Fallani & F Babiloni); An Optimization Approach to the Structure of the Neuronal layout of C elegans (A Arenas et al.); Cultured Neuronal Networks Express Complex Patterns of Activity and Morphological Memory (N Raichman et al.); Synchrony and Precise Timing in Complex Neural Networks (R-M Memmesheimer & M Timme); Networks at the Individual and Population Levels: Ideas for Moving Beyond Structure to Dynamics of Ecological Networks (D B Stouffer et al.); Evolutionary Models for Simple Biosystems (F Bagnoli); Evolution of Cooperation in Adaptive Social Networks (S Van Segbroeck et al.); From Animal Collectives and Complex Networks to Decentralized Motion Control Strategies (A Buscarino et al.); Interplay of Network State and Topology in Epidemic Dynamics (T Gross). Readership: Advanced undergraduates, graduate students and researchers interested in the study of complex networks in a wide range of biological processes and systems."

This second review volume is a follow-up to the book “Engineering of Chemical Complexity” that appeared in 2013. Co-edited by the Nobel laureate Gerhard Ertl, this book provides a broad perspective over the current research aimed at understanding, the design and control of complex chemical systems of various origins, on the scales ranging from single molecules and nano-phenomena to macroscopic chemical reactors. Self-organization behavior and emergence of coherent collective dynamics in reaction-diffusion systems, in active soft matter and biochemical networks are discussed. Special attention is paid to applications in cell biology, to molecular motors and microfluidics effects. The reviews, prepared by leading international experts from the EU, USA, Russia and Japan, together yield a fascinating picture of a rapidly developing research discipline that brings chemical engineering to new frontiers.