Application Of Radiomics In Understanding Tumor Biological Behaviors And Treatment Response

This collection of 25 research papers comprised of 22 original articles and 3 reviews is brought together from international leaders in bioinformatics and biostatistics. The collection highlights recent computational advances that improve the ability to analyze highly complex data sets to identify factors critical to cancer biology. Novel deep learning algorithms represent an emerging and highly valuable approach for collecting, characterizing and predicting clinical outcomes data. The collection highlights several of these approaches that are likely to become the foundation of research and clinical practice in the future. In fact, many of these technologies reveal new insights about basic cancer mechanisms by integrating data sets and structures that were previously immiscible. Accordingly, the series presented here bring forward a wide range of artificial intelligence approaches and statistical methods that can be applied to imaging and genomics data sets to identify previously unrecognized features that are critical for cancer. Our hope is that these articles will serve as a foundation for future research as the field of cancer biology transitions to integrating electronic health record, imaging, genomics and other complex datasets in order to develop new strategies that improve the overall health of individual patients.

The rapid development of artificial intelligence technology in medical data analysis has led to the concept of radiomics. This book introduces the essential and latest technologies in radiomics, such as imaging segmentation, quantitative imaging feature extraction, and machine learning methods for model construction and performance evaluation, providing invaluable guidance for the researcher entering the field. It fully describes three key aspects of radiomic clinical practice: precision diagnosis, the therapeutic effect, and prognostic evaluation, which make radiomics a powerful tool in the clinical setting. This book is a very useful resource for scientists and computer engineers in machine learning and medical image analysis, scientists focusing on antineoplastic drugs, and radiologists, pathologists, oncologists, as well as surgeons wanting to understand radiomics and its potential in clinical practice. An introduction to the concepts of radiomics In-depth presentation of the core technologies and methods Summary of current radiomics research, perspective on the future of radiomics and the challenges ahead An introduction to several platforms that are planned to be built: cooperation, data sharing, software, and application platforms

Precision Medicine for Investigators, Practitioners and Providers addresses the needs of investigators by covering the topic as an umbrella concept, from new drug trials to wearable diagnostic devices, and from pediatrics to psychiatry in a manner that is up-to-date and authoritative. Sections include broad coverage of concerning disease groups and ancillary information about techniques, resources and consequences. Moreover, each chapter follows a structured blueprint, so that multiple, essential items are not overlooked. Instead of simply concentrating on a limited number of extensive and pedantic coverages, scholarly diagrams are also included. Provides a three-pronged approach to precision medicine that is focused on investigators, practitioners and healthcare providers Covers disease groups and ancillary information about techniques, resources and consequences Follows a structured blueprint, ensuring essential chapters items are not overlooked

This essential text provides a readable yet sophisticated overview of the basic concepts of information technologies as they apply in healthcare. Spanning areas as diverse as the electronic medical record, searching, protocols, and communications as well as the Internet, Enrico Coiera has succeeded in making this vast and complex area accessible and understandable to the non-specialist, while providing everything that students of medical informatics need to know to accompany their course.

Radiomics and Radiogenomics: Technical Basis and Clinical Applications provides a first summary of the overlapping fields of radiomics and radiogenomics, showcasing how they are being used to evaluate disease characteristics and correlate with treatment response and patient prognosis. It explains the fundamental principles, technical bases, and clinical applications with a focus on oncology. The book’s expert authors present computational approaches for extracting imaging features that help to detect and characterize disease tissues for improving diagnosis, prognosis, and evaluation of therapy response. This book is intended for audiences including imaging scientists, medical physicists, as well as medical professionals and specialists such as diagnostic radiologists, radiation oncologists, and medical oncologists. Features Provides a first complete overview of the technical underpinnings and clinical applications of radiomics and radiogenomics Shows how they are improving diagnostic and prognostic decisions with greater efficacy Discusses the image informatics, quantitative imaging, feature extraction, predictive modeling, software tools, and other key areas Covers applications in oncology and beyond, covering all major disease sites in separate chapters Includes an introduction to basic principles and discussion of emerging research directions with a roadmap to clinical translation

This issue of Neuroimaging Clinics of North America focuses on Dual Energy CT: Applications in Neurologic, Head and Neck Imaging, and is edited by Drs. Reza Forghani and Hillary R. Kelly. Articles will include: Dual Energy CT: Physical Principles and Approaches to Scanning, Part 1; Dual Energy CT: Physical Principles and Approaches to Scanning, Part 2; Dual Energy CT Applications for Differentiation of Intracranial Hemorrhage, Calcium, and Iodine; Dual Energy CT Angiography of the Head and Neck and Related Applications; Miscellaneous and Emerging Applications of Dual Energy CT for the Evaluation of Intracranial Pathology; Applications of Dual Energy CT for the Evaluation of Head and Neck Squamous Cell Carcinoma; Dual Energy CT Applications for the Evaluation of Cervical Lymphadenopathy; Miscellaneous and Emerging Applications of Dual Energy CT for the Evaluation of Pathologies in the Head and Neck; Dual Energy CT Applications for the Evaluation of the Spine; Applications of Dual Energy CT for Artifact Reduction in the Head, Neck, and Spine; Advanced Tissue Characterization and Texture Analysis using Dual Energy CT: Horizons and Emerging Applications; and more!