Applications Of Ion Chromatography For Pharmaceutical And Biological Products

This is a comprehensive source of information on the application of ion chromatography (IC) in the analysis of pharmaceutical drugs and biologicals. This book, with contributors from academia, pharma, the biotech industry, and instrument manufacturing, presents the different perspectives, experience, and expertise of the thought leaders of IC in a comprehensive manner. It explores potential IC applications in different aspects of product development and quality control testing. In addition, an appendix section gives information on critical physical and chromatographic parameters related to IC and information on current manufacturers of IC systems, columns, and other components.

Ion Chromatography: Instrumentation, Techniques and Applications, Volume 13 in the series Separation Science and Technology, provides a modern overview of all aspects of ion chromatography instrumentation and chemistry techniques, including the historical backdrop of some of the key developments. Most existing books on ion chromatography are focused on single column ion chromatography (rarely used today) or applications, or are outdated. This book covers the broad range of technologies in use and explains the advantages of each, helping both experienced and new practitioners to choose the method they need. The editors of this book have all played a key role in the success of ion chromatography at Dionex Corporation, the undisputed leader in ion chromatography for more than 40 years, and are in a unique position to describe both the technology and its applications. Ion chromatography is the technique of choice for analyzing ionic or ionizable compounds in various industries, such as pharmaceuticals and food. In addition, it is very useful for monitoring cationic or anionic impurities in drinking water. Covers the broad range of technologies currently used in ion chromatography, with an explanation of not only how the technology works, but also which commonly used approaches represent the best options Provides a solid introduction for new practitioners to improve background knowledge on troubleshooting skills Serves as a comprehensive overview of all approaches in ion chromatography, describing the advantages of various newer technology options over older methodologies still in wide use

Introduces the reader to the field of ion chromatography, species analysis and hyphenated methods IC-MS and IC-ICP-MS including the theory and theirs applications Covers the importance of species analysis and hyphenated methods in ion chromatography Includes practical applications of IC-MS and IC-ICP-MS in environmental analysis Details sample preparation methods for ion chromatography Discusses hyphenated methods IC-MS and IC-ICP-MS used in determining both the total element contents and its elements Details speciation analysis used in studying biochemical cycles of selected chemical compounds; determining toxicity and ecotoxicity of elements; food and pharmaceuticals quality control; and in technological process control and clinical analytics

Liquid Chromatography: Applications, Third Edition delivers a single source of authoritative information on all aspects of the practice of modern liquid chromatography. The text gives those working in academia and industry the opportunity to learn, refresh, and deepen their understanding of the field by covering basic and advanced theoretical concepts, recognition mechanisms, conventional and advanced instrumentation, method development, data analysis, and more. This third edition addresses new developments in the field with updated chapters from expert researchers. The book is a valuable reference for research scientists, teachers, university students, industry professionals in research and development, and quality control managers. Emphasizes the integration of chromatographic methods and sample preparation Provides important data related to complex matrices, sample preparation, and data handling Covers the most interesting and valuable applications in different fields, e.g., proteomic, metabolomics, foodomics, pollutants and contaminants, and drug analysis (forensic, toxicological, pharmaceutical, biomedical) Offers comprehensive updates to all chapters Adds new chapters on selection of liquid chromatographic mode, proteomics, doping analysis, analysis of microplastics, and analysis of pharmaceutically and biologically relevant isoforms

This book presents the applications of ion-exchange materials in the biomedical industries. It includes topics related to the application of ion exchange chromatography in determination, extraction and separation of various compounds such as amino acids, morphine, antibiotics, nucleotides, penicillin and many more. This title is a highly valuable source of knowledge on ion-exchange materials and their applications suitable for postgraduate students and researchers but also to industrial R&D specialists in chemistry, chemical, and biochemical technology. Additionally, this book will provide an in-depth knowledge of ion-exchange column and operations suitable for engineers and industrialists.

Carbohydrate Analysis by Modern Liquid Phase Separation Techniques, Second Edition, presents readers with the various principles of modern liquid phase separation techniques and their contributions to the analysis of complex carbohydrates and glycoconjugates. In a selection of all-new chapters, this fully updated volume covers each technique in detail. The book aims to help analysts solve any of the many practical problems they may face in tackling the analysis of carbohydrates. In addition, it addresses current difficulties that must be resolved in carbohydrate research, thus inspiring further important technological developments to meet these challenges. This is an essential resource for anyone seeking a broad view of the science of carbohydrates and separation techniques. Covers the basic principles of modern liquid phase separation techniques, along with their applications Compiles up-to-date information on the field of carbohydrate analysis, along with updates on separation science Focuses on problems currently faced in carbohydrate analysis and the solutions necessary for further progress

This book is characterized by three important features. The authors represent an impressive collection of international workers from Brazil, China, Egypt, Poland, Turkey, and the United States. The majority of the chapters reflect the importance of collaborative efforts in contemporary research. Finally, some chapters are especially useful because of the experimental details that are provided. And it is to be hoped that readers will find that the chapters are both informative and inspirational.