Applied Statistics With Applications In Epidemiological Studies

This textbook provides the basic concepts of epidemiology while preparing readers with the skills of applying statistical tools in real-life situations. Students, in general, struggle with statistical theories and their practical applications. This book makes statistical concepts easy to understand by focusing on real-life examples, case studies, and exercises. It also provides step-by-step guides for data analysis and interpretation using standard statistical software such as SPSS, SAS, R, Python, and GIS as appropriate, illustrating the concepts. Through the book's 23 chapters, readers primarily learn how to apply statistical methods in epidemiological studies and problem-solving. Among the topics covered: Clinical Trials Epidemic Investigation and Control Geospatial Applications in Epidemiology Survival Analysis and Applications Using SAS and SPSS Systematic Review and Meta-Analysis: Evidence-based Decision-Making in Public Health Missing Data Imputation: A Practical Guide Artificial Intelligence and Machine Learning Multivariate Linear Regression and Logistics Regression Analysis Using SAS Each chapter is written by eminent scientists and experts worldwide, including contributors from institutions in the United States, Canada, Bangladesh, India, Hong Kong, Malaysia, and the Middle East. Statistical Approaches for Epidemiology: From Concept to Application is an all-in-one book that serves as an essential text for graduate students, faculty, instructors, and researchers in public health and other branches of health sciences, as well as a useful resource for health researchers in industry, public health and health department professionals, health practitioners, and health research organizations and non-governmental organizations. The book also will be helpful for graduate students and faculty in related disciplines such as data science, nursing, social work, environmental health, occupational health, computer science, statistics, and biology.

Epidemiologic studies provide research strategies for investigating public health and scientific questions relating to the factors that cause and prevent ailments in human populations. Statistics in Epidemiology: Methods, Techniques and Applications presents a comprehensive review of the wide range of principles, methods and techniques underlying prospective, retrospective and cross-sectional approaches to epidemiologic studies. Written for epidemiologists and other researchers without extensive backgrounds in statistics, this new book provides a clear and concise description of the statistical tools used in epidemiology. Emphasis is given to the application of these statistical tools, and examples are provided to illustrate direct methods for applying common statistical techniques in order to obtain solutions to problems. Statistics in Epidemiology: Methods, Techniques and Applications goes beyond the elementary material found in basic epidemiology and biostatistics books and provides a detailed account of techniques:

Applied statistics is more than data analysis, but it is easy to lose sight of the big picture. David Cox and Christl Donnelly distil decades of scientific experience into usable principles for the successful application of statistics, showing how good statistical strategy shapes every stage of an investigation. As you advance from research or policy question, to study design, through modelling and interpretation, and finally to meaningful conclusions, this book will be a valuable guide. Over a hundred illustrations from a wide variety of real applications make the conceptual points concrete, illuminating your path and deepening your understanding. This book is essential reading for anyone who makes extensive use of statistical methods in their work.

"This very informative book introduces classical and novel statistical methods that can be used by theoretical and applied biostatisticians to develop efficient solutions for real-world problems encountered in clinical trials and epidemiological studies. The authors provide a detailed discussion of methodological and applied issues in parametric, semi-parametric and nonparametric approaches, including computationally extensive data-driven techniques, such as empirical likelihood, sequential procedures, and bootstrap methods. Many of these techniques are implemented using popular software such as R and SAS."— Vlad Dragalin, Professor, Johnson and Johnson, Spring House, PA "It is always a pleasure to come across a new book that covers nearly all facets of a branch of science one thought was so broad, so diverse, and so dynamic that no single book could possibly hope to capture all of the fundamentals as well as directions of the field. The topics within the book’s purview—fundamentals of measure-theoretic probability; parametric and non-parametric statistical inference; central limit theorems; basics of martingale theory; Monte Carlo methods; sequential analysis; sequential change-point detection—are all covered with inspiring clarity and precision. The authors are also very thorough and avail themselves of the most recent scholarship. They provide a detailed account of the state of the art, and bring together results that were previously scattered across disparate disciplines. This makes the book more than just a textbook: it is a panoramic companion to the field of Biostatistics. The book is self-contained, and the concise but careful exposition of material makes it accessible to a wide audience. This is appealing to graduate students interested in getting into the field, and also to professors looking to design a course on the subject." — Aleksey S. Polunchenko, Department of Mathematical Sciences, State University of New York at Binghamton This book should be appropriate for use both as a text and as a reference. This book delivers a "ready-to-go" well-structured product to be employed in developing advanced courses. In this book the readers can find classical and new theoretical methods, open problems and new procedures. The book presents biostatistical results that are novel to the current set of books on the market and results that are even new with respect to the modern scientific literature. Several of these results can be found only in this book.

A one-stop guide for public health students and practitioners learning the applications of classical regression models in epidemiology This book is written for public health professionals and students interested in applying regression models in the field of epidemiology. The academic material is usually covered in public health courses including (i) Applied Regression Analysis, (ii) Advanced Epidemiology, and (iii) Statistical Computing. The book is composed of 13 chapters, including an introduction chapter that covers basic concepts of statistics and probability. Among the topics covered are linear regression model, polynomial regression model, weighted least squares, methods for selecting the best regression equation, and generalized linear models and their applications to different epidemiological study designs. An example is provided in each chapter that applies the theoretical aspects presented in that chapter. In addition, exercises are included and the final chapter is devoted to the solutions of these academic exercises with answers in all of the major statistical software packages, including STATA, SAS, SPSS, and R. It is assumed that readers of this book have a basic course in biostatistics, epidemiology, and introductory calculus. The book will be of interest to anyone looking to understand the statistical fundamentals to support quantitative research in public health. In addition, this book: • Is based on the authors’ course notes from 20 years teaching regression modeling in public health courses • Provides exercises at the end of each chapter • Contains a solutions chapter with answers in STATA, SAS, SPSS, and R • Provides real-world public health applications of the theoretical aspects contained in the chapters Applications of Regression Models in Epidemiology is a reference for graduate students in public health and public health practitioners. ERICK SUÁREZ is a Professor of the Department of Biostatistics and Epidemiology at the University of Puerto Rico School of Public Health. He received a Ph.D. degree in Medical Statistics from the London School of Hygiene and Tropical Medicine. He has 29 years of experience teaching biostatistics. CYNTHIA M. PÉREZ is a Professor of the Department of Biostatistics and Epidemiology at the University of Puerto Rico School of Public Health. She received an M.S. degree in Statistics and a Ph.D. degree in Epidemiology from Purdue University. She has 22 years of experience teaching epidemiology and biostatistics. ROBERTO RIVERA is an Associate Professor at the College of Business at the University of Puerto Rico at Mayaguez. He received a Ph.D. degree in Statistics from the University of California in Santa Barbara. He has more than five years of experience teaching statistics courses at the undergraduate and graduate levels. MELISSA N. MARTÍNEZ is an Account Supervisor at Havas Media International. She holds an MPH in Biostatistics from the University of Puerto Rico and an MSBA from the National University in San Diego, California. For the past seven years, she has been performing analyses for the biomedical research and media advertising fields.

Statistics are a vital skill for epidemiologists and form an essential part of clinical medicine. This textbook introduces students to statistical epidemiology methods in a carefully structured and accessible format with clearly defined learning outcomes and suggested chapter orders that can be tailored to the needs of students at both undergraduate and graduate level from a range of academic backgrounds. The book covers study design, disease measuring, bias, error, analysis and modelling and is illustrated with figures, focus boxes, study questions and examples applicable to everyday clinical problems. Drawing on the authors' extensive teaching experience, the text provides an introduction to core statistical epidemiology that will be a valuable resource for students and lecturers in health and medical sciences and applied statistics, health staff, clinical researchers and data managers.

Routine applications of advanced statistical methods on real data have become possible in the last ten years because desktop computers have become much more powerful and cheaper. However, proper understanding of the challenging statistical theory behind those methods remains essential for correct application and interpretation, and rarely seen in the medical literature. Modern Methods for Epidemiology provides a concise introduction to recent development in statistical methodologies for epidemiological and biomedical researchers. Many of these methods have become indispensible tools for researchers working in epidemiology and medicine but are rarely discussed in details by standard textbooks of biostatistics or epidemiology. Contributors of this book are experienced researchers and experts in their respective fields. This textbook provides a solid starting point for those who are new to epidemiology, and for those looking for guidance in more modern statistical approaches to observational epidemiology. Epidemiological and biomedical researchers who wish to overcome the mathematical barrier of applying those methods to their research will find this book an accessible and helpful reference for self-learning and research. This book is also a good source for teaching postgraduate students in medical statistics or epidemiology.