Bioactive Compounds From Microbes
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Bioactive Compounds from Microbes
Author | : Roberto Mazzoli,Katharina Riedel,Enrica Pessione |
Publsiher | : Frontiers Media SA |
Total Pages | : 144 |
Release | : 2017-06-02 |
Genre | : Electronic book |
ISBN | : 9782889451852 |
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Microorganisms have had a long and surprising history. They were “invisible” until invention of microscope in the 17th century. Until that date, although they were extensively (but inconsciously) employed in food preservation, beer and wine fermentation, cheese, vinegar, yogurt and bread making, as well as being the causative agents of infectious diseases, they were considered as “not-existing”. The work of Pasteur in the middle of the 19th century revealed several biological activities performed by microorganisms including fermentations and pathogenicity. Due to the urgent issue to treat infectious diseases (the main cause of death at those times) the “positive potential” of the microbial world has been neglected for about one century. Once the fight against the “evil” strains was fulfilled also thanks to the antibiotics, industry began to appreciate bacteria’s beneficial characteristics and exploit selected strains as starters for both food fermentations and aroma, enzyme and texturing agent production. However, it was only at the end of the 20th century that the probiotic potential of some bacteria such as lactic acid bacteria and bifidobacteria was fully recognized. Very recently, apart from the probiotic activity of in toto bacteria, attention has begun to be directed to the chemical mediators of the probiotic effect. Thanks also to the improvement of techniques such as transcriptomics, proteomics and metabolomics, several bioactive compounds are continuously being discovered. Bioactive molecules produced by bacteria, yeasts and virus-infected cells proved to be important for improving or impairing human health. The most important result of last years’ research concerns the discovery that a very complex network of signals allows communication between organisms (from intra-species interactions to inter-kingdom signaling). Based on these findings a completely new approach has arisen: the system biology standpoind. Actually, the different organisms colonizing a certain environmental niche are not merely interacting with each other as individuals but should be considered as a whole complex ecosystem continuously exchanging information at the molecular level. In this context, this topic issue explores both antagonistic compounds (i.e. antibiotics) and “multiple function” cooperative molecules improving the physiological status of both stimulators and targets of this network. From the applicative viewpoint, these molecules could be hopefully exploited to develop new pharmaceuticals and/or nutraceuticals for improving human health.
The Search for Bioactive Compounds from Microorganisms
Author | : Satoshi Omura |
Publsiher | : Springer Science & Business Media |
Total Pages | : 373 |
Release | : 2012-12-06 |
Genre | : Science |
ISBN | : 9781461244127 |
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Biologically active compounds isolated from microorganisms continue to be vital to the development of new drugs and agricultural chemicals. This book was prepared by current and past members of the laboratory of Dr. Satoshi Omura of the Kitasato Institute in Japan. Dr. Omura and his colleagues have discovered and studied a number of important antibiotics, and in their work they have pioneered new methods for screening microbes for interesting and important compounds. This book presents strategies and methods for identifying novel molecules with several types of biological activity. In addition, the book discusses the identification of microbial compounds of agrochemical importance, presents information on chemical screening methods, and concludes with chapters on microbial strain selection, fermentation technology, and genetic engineering of antibiotic-producing microorganisms. This book will be of great interest to scientists working in the very active and competitive fields of antibiotic and agrochemical discovery.
Marine Microbiology
Author | : Se-Kwon Kim |
Publsiher | : John Wiley & Sons |
Total Pages | : 558 |
Release | : 2013-06-21 |
Genre | : Science |
ISBN | : 9783527665273 |
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Deliberately breaking with the classical biology-centered description of marine organisms and their products, this reference emphasizes microbial technology over basic biology, setting it apart from its predecessors. As such, it systematically covers the technology behind high-value compounds for use as pharmaceuticals, nutraceuticals or cosmetics, from prospecting to production issues. Following a definition of the field, the book goes on to address all industrially important aspects of marine microbial biotechnology. The first main part contains a description of the major production organisms, from archaebacteria to cyanobacteria to algae and symbionts, including their genetic engineering. The remaining four parts look at commercially important compounds produced by these microorganisms together with their applications. Throughout, the emphasis is on technological considerations, and the future potential of these organisms or compound classes is discussed. A valuable and forward-looking resource for innovative biotechnologists in industry as well as in academia.
Bioactive Compounds from Terrestrial Extremophiles
Author | : Lesley-Ann Giddings,David J. Newman |
Publsiher | : Springer |
Total Pages | : 90 |
Release | : 2014-11-21 |
Genre | : Science |
ISBN | : 9783319132600 |
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A discussion of the chemical compounds produced by organisms living under extreme conditions that may have potential as drugs or leads to novel drugs for human use. This SpringerBrief deals with bioactive materials from terrestrial extremophiles.
MICROBIAL TRANSFORMATIONS OF BIOACTIVE COMPOUNDS
Author | : John P. Rosazza |
Publsiher | : CRC Press |
Total Pages | : 152 |
Release | : 1982-07 |
Genre | : Medical |
ISBN | : UOM:39015005998847 |
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Volume 1: Notes on the historical development of microbial transformations; The methodology of microbial transformations of organic compounds; Microbial transformations of antibiotics; Microbial transformation of important industrial hydrocarbons; Microbial transformations of prostaglandins. Volume 2: Microbial transformations as a means of preparing mammalian drug metabolites; Transformations of xenobiotics by the intestinal microflora; Microbial transformations of alkaloids; Microbial transformations of cannabinoids; Microbial transformations of pesticides.
Marine Microorganisms
Author | : Leo M.L. Nollet |
Publsiher | : CRC Press |
Total Pages | : 167 |
Release | : 2016-09-19 |
Genre | : Technology & Engineering |
ISBN | : 9781498702560 |
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The marine environment covers 70% of the earth’s surface and accounts for 98% of the potentially habitable space. The bioactives from marine microorganisms include antibiotic compounds, polysaccharides, inhibitors, enzymes, peptides, and pigments. These are used in various fields of biology that range from nutraceuticals to cosmeceuticals. Recent scientific investigations have revealed that marine microbial compounds exhibit various beneficial biological effects, such as anti-inflammatory, anti-cancer, anti-HIV, anti-hypertensive, and anti-diabetic. Marine Microorganisms: Extraction and Analysis of Bioactive Compounds sheds light on the extraction, clean-up, and detection methods of major compounds from marine organisms. The book includes information on the different classes of marine microorganisms and the different bioactives that can be extracted from bacteria, fungi and microalgae. Divided into 7 chapters, the book covers bioactive marine natural products, such as marine microbes, seaweeds, and marine sponges as potential sources of drug discovery, and focuses on analysis methods of the biocomponents from marine microorganisms. A useful reference tool for researchers and students, this book provides current knowledge about isolation and analysis methods of the bioactives and provides insight into the various bioactives of marine microbes toward nutraceutical and pharmaceutical development.
Bioactive Compounds from Extremophiles
Author | : Lesley-Ann Giddings,David J. Newman |
Publsiher | : Springer |
Total Pages | : 63 |
Release | : 2015-01-07 |
Genre | : Science |
ISBN | : 9783319148366 |
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This SpringerBrief sheds new light on bioactive materials from extremophiles with the focus on the biosynthesis processes and related genomics. It deals with all aspects of the chemical compounds produced by organisms living under extreme conditions that may have potential as drugs or lead to novel drugs for human use.
The Search for Bioactive Compounds from Microorganisms
![The Search for Bioactive Compounds from Microorganisms](https://youbookinc.com/wp-content/uploads/2024/06/cover.jpg)
Author | : Satoshi Ōmura |
Publsiher | : Springer |
Total Pages | : 352 |
Release | : 1992-01-01 |
Genre | : Biological products |
ISBN | : 3540977554 |
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