Biochemistry And Molecular Biology

Uniquely integrates the theory and practice of key experimental techniques for bioscience undergraduates. Now includes drug discovery and clinical biochemistry.

While biomedical investigation has greatly advanced, investigators have lost touch with and inadvertently corrupted significant nomenclature at the foundation of their science. Nowadays, one has to be an insider to even understand the titles of journals, as modern biochemists have a tendency to invent new terms to describe old phenomena and apply a

A concise introductory textbook in biochemistry and molecular biology for life sciences students taking a first course in the topic. Professor William Elliott from University of Adelaide, Dr Daphne Elliott formerly at Flinders University.

A new edition of the popular introductory textbook for biochemistry and molecular biology. * Contains substantial new material * Contains even more of the clear, colour diagrams Completely up to date. Elimination of inessential material has permitted full coverage of the areas of most current interest as well as coverage of essential basic material. Areas of molecular biology such as cell signalling, cancer molecular biology, protein targeting, proteasomes, immune system, eukaryotic gene control are covered fully but still in a clear student friendly style. This makes the book suitable for the most modern type of courses. WHAT'S NEW New or completely re-written chapters - 2. Enzymes 3. The structure of proteins 4. The cell membrane - a structure depending only on weak forces 13. Strategies for metabolic control and their applications to carbohydrate and fat metabolism 17. Cellular disposal of unwanted molecules 23. Eukaryotic gene transcription and control 24. Protein synthesis, intracellular transport and degradation 25. How are newly synthesised proteins delivered to their correct destinations? - Protein targeting 26. Cell signalling 27. The immune system 30. Molecular biology of cancer 33. The cytoskeleton, molecular motors and intracellular transport There are also several major insertions of new material, and minor editing to the rest of the book. SUPPORT MATERIAL ON THE WEB www.oup.com/elliott (look for the site in August 2000) * There will be a sample chapter in November 2000 so that readers can see the design and content * All the illustrations will be available free for downloading (from March 2001) * A detailed description of the purpose of the book: who it's aimed at and why it was written (from August 2000) * A detailed description of what's new to this edition (from August 2000) PLUS Student's Solutions Manual Instructor's Solutions Manual (tbc)

Even though the ApoA5 gene was discovered more than 13 years ago by Pennacchio et al, 2001 [1], and it was known then the gene influences triglycerides, leading to speculations that it would affect the risk of stroke; the factors that affect cardiovascular diseases are very complex. Larry Baum's group shown that APOA5 genotypes were not significantly associated with strokes or stroke subtypes in the cohort they studied [2]. The discovery of the ApoA5 gene was very special in that, unlike many other genes discovered through studying a known protein or enzyme, advanced bioinformatics was used for the initial gene discovery, an amazing feat that could not have been done without knowledge of the human genome. The laborious effort in deciphering the genome was very controversial in its infancy, and voices of opposition nearly led to premature abortion of the project, and much of the objection was voiced due to the doubt of spending a hugh budget in sequencing what was thought to be useless, i.e. for a major proportion (98%) of junk DNA at that time. However, recently it was shown that deleting a non-coding region of what was thought to be junk DNA could lead to narrowing of arteries in mice [3] so that might offer an explanation that there are more to the story of stroke risk factors than merely studying APOA5, and such findings just remind us time and again, often the basic research could laid the foundation that is very essential for discoveries made by clinicians or the translational/applied scientists.

A major update of a best-selling textbook that introduces students to the key experimental and analytical techniques underpinning life science research.

Publisher's Note: Products purchased from 3rd Party sellers are not guaranteed by the Publisher for quality, authenticity, or access to any online entitlements included with the product. Practical, approachable, and perfect for today’s busy medical students and practitioners, BRS Biochemistry, Molecular Biology, and Genetics, Seventh Edition helps ensure excellence in class exams and on the USMLE Step 1. The popular Board Review Series outline format keeps content succinct and accessible for the most efficient review, accompanied by bolded key terms, detailed figures, quick-reference tables, and other aids that highlight important concepts and reinforce understanding. This revised edition is updated to reflect the latest perspectives in biochemistry, molecular biology, and genetics, with a clinical emphasis essential to success in practice. New Clinical Correlation boxes detail the real-world application of chapter concepts, and updated USMLE-style questions with answers test retention and enhance preparation for board exams and beyond.

Progress in wood chemistry has been related mainly to chemical wood pulping and bleaching and chemical utilization of wood and wood extractives. Meth ods of wood analysis were developed by Schorger (proximate analysis in 1917) and Dore (summative analysis in 1919), and standard methods based on Schorger's method, e.g., TAPPI standards (Technical Association of the Pulp and Paper Industry), have been widely used for chemical analysis of woods in many countries. Thus it is generally known that wood is composed of about 50% cellulose, 20-35% of lignin, 15-25% of hemicelluloses, and variable amounts of extractives. Chemical characterization and efficient utilization of these wood components have been studied in laboratories of wood chemistry and technology in universities and government institutions. In the last decade, biochemistry and molecular biology of microorganisms, animals, and plants have greatly progressed. At the same time wood has been recognized as a unique renewable ecomaterial produced by trees using solar energy. In addition, many desirable properties of wood and wood components as biomaterial that affects physiology and psychology in humans have recently attracted attention.