Cardiac Adaptations

This book summarizes present knowledge of different mechanisms involved in the development of positive and negative consequences of cardiac adaptation. Particular attention is paid to the still underestimated adaptive cardiac responses during development, to adaptation to the frequently occurring pressure and volume overload as well as to cardiac changes, induced by enduring exercise and chronic hypoxia. Cardiac Adaptations will be of great value to cardiovascular investigators, who will find this book highly useful in their cardiovascular studies for finding solutions in diverse pathological conditions; it will also appeal to students, fellows, scientists, and clinicians interested in cardiovascular abnormalities.

The effective management of Cardiac remodeling(CR), remains a major challenge. Heart failure remains the leading cause of death in industrialized countries. Yet, despite the enormity of the problem, effective therapeutic interventions remain elusive. In fact, several initially promising agents were found to decrease mortality in patients recovering from myocardial infarction. Cardiac remodeling is defined as molecular and interstitial changes, manifested clinically by changes in size, mass , geometry and function of the heart in response to certain aggression. Initially, ventricular remodeling aims to maintain stable cardiac function in situations of aggression.

This book summarizes present knowledge of different mechanisms involved in the development of positive and negative consequences of cardiac adaptation. Particular attention is paid to the still underestimated adaptive cardiac responses during development, to adaptation to the frequently occurring pressure and volume overload as well as to cardiac changes, induced by enduring exercise and chronic hypoxia. Cardiac Adaptations will be of great value to cardiovascular investigators, who will find this book highly useful in their cardiovascular studies for finding solutions in diverse pathological conditions; it will also appeal to students, fellows, scientists, and clinicians interested in cardiovascular abnormalities.

Sex and Cardiac Electrophysiology: Differences in Cardiac Electrical Disorders Between Men and Women is a comprehensive investigation into all aspects of sex differences in cardiac electrophysiology. As there are substantial differences between female and male patients in physiology, pathology triggering factors, disease progression, clinical approaches and treatment outcome, this book provides a comprehensive examination. In cardiology, the differences between women and men are more recognized, hence this title summarizes these important differences, providing the essential information needed for clinical specialists and researchers involved in the design and implementation of clinical studies. Explores topics ranging from the physiologic differences between women and men to the differences in clinical handling of arrhythmic disorders between female and male patients Provides sex differences in cardiac electrophysiology in separate chapters Covers the sex differences of cardiac electrical disorders, providing insights beyond cardiac metabolic syndrome, hypertension, atherogenesis and heart failure

Written for students and professionals working within exercise science and related health professions, AdvancedCardiovascular Exercise Physiology systematically details the effect of acute and chronic exercise training on each component of the cardiovascular system: the heart, the vasculature, and the blood (including blood clotting factors). Readers will gain a comprehensive understanding of the cardiovascular system and learn how to apply this knowledge to their work with athletes, other active individuals, and patients who have cardiovascular risk factors. Advanced Cardiovascular Exercise Physiology highlights the complex interaction of the components of the cardiovascular system both at rest and during exercise. Using the latest scientific and medical research, this text presents engaging discussion of cardiovascular responses and adaptions to both acute and chronic aerobic and resistance exercise training. In addition, specific attention is paid to the beneficial effects of exercise on the components of the cardiovascular system and the mechanisms through which regular exercise provides cardioprotection. Each chapter contains a summary to highlight key content, important terms bolded within the text for quick reference, and a key terms section at the end of each chapter defining all the bolded terms. In addition, sidebars within each chapter describe real-world examples and applications. Richly illustrated, Advanced Cardiovascular Exercise Physiology uses extensive figures and graphics to elucidate physiological mechanisms and to depict exercise responses and training adaptations. This text is divided into two sections, beginning with a concise explanation of the structure and function of each component of the cardiovascular system. In the second section, readers encounter detailed discussion of the acute and chronic effects of aerobic and resistance exercise on cardiac function, vascular function, and hemostatic variables. Advanced Cardiovascular Exercise Physiology provides a framework for understanding how the components of the cardiovascular system cooperate to support exercise and how those components adapt to and benefit from a systematic program of exercise training. By presenting current research that elucidates the specific effects and benefits of exercise on the cardiovascular system, Advanced Cardiovascular Exercise Physiology also offers readers possible future directions for research. Human Kinetics’ Advanced Exercise Physiology series offers books for advanced undergraduate and graduate students as well as professionals in exercise science and kinesiology. These books highlight the complex interaction of the various systems both at rest and during exercise. Each text in this series offers a concise explanation of the system and details how each is affected by acute exercise and chronic exercise training. Advanced Cardiovascular Exercise Physiology is the second volume in the series.

Cardiac hypertrophy and accompanying phenomena have received increasing attention in recent years - particularly in the basic sciences. The present volume contains the proceedings of the Erwin RIESCH SYMPOSIUM on "CARDIAC ADAPTATION TO HEMODYNAMIC OVERLOAD, TRAINING AND STRESS" held in Tiibingen on Sep tember 19-22, 1982. In addition to the topics of the previous symposia (1976 and 1979) concerned with problems of cardiac hypertrophy, the scope of this sequel meeting has been expanded to include related fields. The intention was to consider numerous related features and problems of chronic reactions of the heart (and vascular system) to abnormal hemodynamic loading, as well as alterations due to maturation, aging, training, neuroendocrine status and stress. Special attention has been paid to cardiac reactions at the level of contractile proteins. The results are considered primarily in light of long-term adaptation of the heart. Of course, research at the forefront of current knowledge need not always lead to congruent conclusions. Neither can the individual contributions always agree with the viewpoint of the editors. However, the broad array of individual approaches employed by biochemists, biolo gists, pathologists, physiologists, pharmacologists and clinical cardio logists will certainly help to provide a more balanced interpretation of the results in individual fields, stimulate reexamination of established con cepts and provide direction for future research.

This title is directed primarily towards health care professionals outside of the United States. Written by an eminent cardiovascular physiologist with a strong track record in dealing with issues related to exercise and environmental physiology, this text covers cardiovascular function from the exercise and human physiologist's viewpoint. It provides a solid foundation of knowledge of how the cardiovascular system responds and adapts to the challenges of exercise and environmental change, and analyses the practicalities of measuring cardiovascular parameters in normal human subjects. Case studies in exercise physiology throughout text. Open-ended questions at end of each chapter encourage students to explore common situations facing exercise and human physiologists. Bibliography at end of each chapter directs students to further reading resources. Summaries at start of each chapter and multiple choice questions with explanatory answers at end of book aid revision and help students test their knowledge.