Cell Mechanics During Phagocytosis Studied By Optical Tweezers Based Microscopy

"Adhesion of Cells, Viruses and Nanoparticles" describes the adhesion of cells, viruses and nanoparticles starting from the basic principles of adhesion science, familiar to postgraduates, and leading on to recent research results. The underlying theory is that of van der Waals forces acting between cells and substrates, embodied in the molecules lying at the surfaces, together with the geometry and elasticity of the materials involved. The first part describes the fundamental background to adhesion principles, including the phenomenology, the important equations and the modeling ideas. Then the mechanisms of adhesion are explored in the second part, including the elastic deformations of spheres and the importance of the energy of adhesion as measured in various tests. It is demonstrated that adhesion of cells is statistical and depends on Brownian movement and on the complex multiple contacts that can form as cells move around. Then, detailed chapters on cell adhesion, contact of viruses and aggregation of nanoparticles follow in Part 3. Finally, the last chapter looks to the future understanding of cell adhesion and points out some interesting directions of research, development and treatment of diseases related to these phenomena. This book is an ideal resource for researchers on adhesion molecules, receptors, cell and tissue culturing, virus infection, toxicity of nanoparticles and bioreactor fouling. It can also be used to support undergraduate and Masters level teaching courses. "This is a fascinating book and it is an invaluable resource for understanding particle-particle/surface adhesion at micro- and nano- scales. I intend to keep one for my future reference and highly recommend it to my students." (Prof. Zhibing Zhang, School of Chemical Engineering, University of Birmingham, UK)

Handbook of Antimicrobial Coatings is the first comprehensive work on the developments being made in the emerging field of antimicrobial coatings. Crucial aspects associated with coating research are presented in the form of individual chapters. Particular close attention has been given to essential aspects necessary to understand the properties of novel materials. The book introduces the reader to progress being made in the field, followed by an outline of applications in different areas. Various methods and techniques of synthesis and characterization are detailed as individual chapters. Chapters provide insight into the ongoing research, current trends and technical challenges in this rapidly progressing field. The covered topics were chosen so that they can be easily understood by new scholars as well as advanced learners. No book has been written on this topic thus far with so much crucial information for materials scientists, engineers and technologists. Offers the first comprehensive work on developments being made in the emerging field of antimicrobial coatings Features updates written by leading experts in the field of anti-microbial coatings Includes discussions of coatings for novel materials Provides various methods and techniques of synthesis and characterization detailed in individual chapters

Shortlisted for the 2023 Royal Society Science Book Prize A structural engineer examines the seven most basic building blocks of engineering that have shaped the modern world. Some of humanity’s mightiest engineering achievements are small in scale—and, without them, the complex machinery on which our modern world runs would not exist. In Nuts and Bolts, structural engineer Roma Agrawal examines seven of these extraordinary elements: the nail, the wheel, the spring, the magnet, the lens, the string, and the pump. Tracing the evolution from Egyptian nails to modern skyscrapers, and Neanderthal string to musical instruments, Agrawal shows us how even our most sophisticated items are built on the foundations of these ancient and fundamental breakthroughs. She explores an array of intricate technologies—dishwashers, spacesuits, microscopes, suspension bridges, breast pumps—making surprising connections, explaining how they work, and using her own hand-drawn illustrations to bring complex principles to life. Alongside deeply personal experiences, she recounts the stories of remarkable—and often uncredited—scientists, engineers, and innovators from all over the world, and explores the indelible impact these creators and their creations had on society. In preindustrial Britain, nails were so precious that their export to the colonies was banned—and women were among the most industrious nail makers. The washing machine displayed at an industrial fair in Chicago in 1898 was the only machine featured that was designed by a woman. The history of the wheel, meanwhile, starts with pottery, and takes us to India’s independence movement, where making clothes using a spinning wheel was an act of civil disobedience. Eye-opening and engaging, Nuts and Bolts reveals the hidden building blocks of our modern world, and shows how engineering has fundamentally changed the way we live.

Once the second edition was safely off to the printer, the 110 larger world of micro-CT and micro-MRI and the smaller world authors breathed a sigh of relief and relaxed, secure in the belief revealed by the scanning and transmission electron microscopes. that they would “never have to do that again. ” That lasted for 10 To round out the story we even have a chapter on what PowerPoint years. When we ?nally awoke, it seemed that a lot had happened. does to the results, and the annotated bibliography has been In particular, people were trying to use the Handbook as a text- updated and extended. book even though it lacked the practical chapters needed. There As with the previous editions, the editor enjoyed a tremendous had been tremendous progress in lasers and ?ber-optics and in our amount of good will and cooperation from the 124 authors understanding of the mechanisms underlying photobleaching and involved. Both I, and the light microscopy community in general, phototoxicity. It was time for a new book. I contacted “the usual owe them all a great debt of gratitude. On a more personal note, I suspects” and almost all agreed as long as the deadline was still a would like to thank Kathy Lyons and her associates at Springer for year away.

MBC online publishes papers that describe and interpret results of original research conserning the molecular aspects of cell structure and function.