Cell Traffic

Cell Traffic presents new poems and uncollected prose poetry along with selected work from award-winning poet Heid Erdrich's three previous poetry collections. Erdrich's new work reflects her continuing concerns with the tensions between science and tradition, between spirit and body. She finds surprising common ground while exploring indigenous experience in multifaceted ways: personal, familial, biological, and cultural. The title, Cell Traffic, suggests motion and Erdrich considers multiple movements-cellular transfer, the traffic of DNA through body parts and bones, "migration" through procreation, and the larger "movements" of indigenousness and ancestral inheritance.ÊErdrich's wry sensibility, sly wit, and keenly insightful mind have earned her a loyal following. Her point of view is always slightly off center, and this lends a particular freshness to her poetry. The debunking and debating of the science of origins is one of Erdrich's focal subjects. In this collection, she turns her observational eye to the search for a genetic mother of humanity, forensic anthropology's quest for the oldest known bones, and online offers of genetic testing. But her interests are not limited to science. She freely admits popular culture into her purview as well, referencing sci-fi television series and Internet pop-up ads.

Although mechanisms involved in the spread of cancer have been the subject of a major research endeavor over the past decade, metastatic tumors still account for significant clinical morbidity and the failure of cancer treatment. Not only are the vascular pathways the most common route for the dissemination of cancer cells, but interactions between the cells and the circulation act as important rate-regulators for the metastatic process. This authoritative, multi-authored volume addresses the importance of microcirculation in cancer metastasis. The book begins with up-to-date reviews on the biology of endothelial cells and the structure and physiology of the normal and tumor microcirculations, and then emphasizes interactions between components of the microcirculation and cancer cells. Metastasis is discussed through chapters exploring the entry of cancer cells into the circulation, the biophysics and morphology of cancer cell traffic and arrest, interactions with host cells and the basement membranes, and angiogenesis. This fascinating book will interest oncologists, pathologists, and students of metastasis or the microcirculation.

In attempts to reduce greenhouse gas emissions, many alternatives to manufacturing have been recommended from a number of international organizations. Although challenges will arise, remanufacturing has the ability to transform ecological and business value. Computational Intelligence in Remanufacturing introduces various computational intelligence techniques that are applied to remanufacturing-related issues, results, and lessons from specific applications while highlighting future development and research. This book is an essential reference for students, researchers, and practitioners in mechanical, industrial, and electrical engineering.

International Review of Cell and Molecular Biology presents comprehensive reviews and current advances in cell and molecular biology. The series has a worldwide readership, maintaining a high standard by publishing invited articles on important and timely topics authored by prominent cell and molecular biologists. Provides comprehensive reviews and current advances Presents a wide range of perspectives on specific subjects Contains valuable reference material for advanced undergraduates, graduate students, and professional scientists

As wireless users have become increasingly mobile, tracking their location and establishing communications links between them have become critical. Location management, paging and routing are the key technologies for performing these crucial functions. This comprehensive work examines past, present and future advances in location management and routing protocols for both single-hop and multi-hop mobile wireless networks.

CHAPEL AND HAENEY’S ESSENTIALS OF CLINICAL IMMUNOLOGY The Essentials are an international, best-selling series of textbooks, all of which are designed to support lecture series or themes on core topics within the health sciences. See www.wiley.com for further details. The fully updated new edition of the classic textbook, introducing the pathophysiology and management of immunological disorders Chapel and Haeney’s Essentials of Clinical Immunology contains the knowledge necessary to understand the diagnosis and treatment of immunological disorders. With easy-to-read text and a wealth of colour clinical images and diagrams, this well-regarded textbook introduces complex concepts using effective pedagogical tools such as bulleted lists, key point boxes, real-life case studies, practical examples, figures and tables, chapter introductions, and keywords in bold integrated in each chapter. Fully updated throughout, the seventh edition provides up-to-date coverage of the clinical relevance that immunology has in medicine. These new and revised sections examine current research trends, the implementation of automation in laboratories, the emerging field of neuro-psychiatric disorders such as NMDA receptor encephalitis and more. This edition includes new end-of-chapter summaries, updated clinical information, additional real-life case histories illustrating key concepts, and linking immunological testing to diseases. The new edition also includes: Covers the investigations required for diagnosis of immunological disorders and for management of patients Describes what occurs when diagnosing conditions in real-world laboratories Features case studies highlighting the connections between immunological theory and clinical cases Includes an updated companion website that features: case studies, interactive questions, photographs, illustrations, web links and review articles from the journal Clinical and Experimental Immunology Chapel and Haeney’s Essentials of Clinical Immunology is an ideal resource for clinical medical students, junior doctors, medical residents and other medical professionals who are looking to expand or refresh their knowledge in clinical immunology, as well as being an excellent introductory textbook for undergraduate courses in the subject. For more information on the complete range of Wiley medical student and junior doctor publishing, please visit: www.wiley.com To receive automatic updates on Wiley books and journals, join our email list. Sign up today at www.wiley.com/email All content reviewed by students for students Wiley Medical Education books are designed exactly for their intended audience. All of our books are developed in collaboration with students. This means that our books are always published with you, the student, in mind If you would like to be one of our student reviewers, go to www.reviewmedicalbooks.com to find out more. This title is also available as an e-book. For more details, please see www.wiley.com/buy/9781119542384

Volume 71 of Advances in Cancer Research begins with Morgan and Kastan presenting data on the roles of p53 and ATM in cell cycle progression and cell death in response to DNA damage and how this information may lead to targets for improved cancer therapies. Kok et all. Review the methodological advantages and limitations to localizing tumor suppressor genes, especially those on the short arm of chromosome 3. Peltomaki and de la Chapelle describe research on mismatch repair genes and their effects on colorectal cancer. McKenna and Cotter present findings on the functions and failures of apoptosis in the hematopoietic system. Ravitz and Wenner review TGF-B and how it controls and affects cell cycle progression in a variety of cell types. Andrew Simpson presents data on the mutation frequencies of microsatellites in human carcinogenesis. Naor and colleagues present research on a multitude of tumors expressing levels of CD44 and discuss how CD44 may be used as a target for cancer therapy. Luisa Villa discusses various aspects of HPV and the potential clinical use of HPV testing in cervical cancer prevention programs. Last, Disis and Cheever review the studies that define HER-2/neu specific immunity in patients with cancer and the current vaccine strategies for generating specific immunity.