Chemical And Biological Microsensors

This book reviews the state of art in the field of chemical sensors for analyses of ionic or molecular species dissolved in liquid media, mainly in aqueous solutions. The transduction of such devices is based on chemical, biological and physical phenomena. The fundamental phenomena involved in these sensors are described in the different chapters by specialists having a good expertise in the field. Numerous recent bibliographic references are given. Most of the devices could be miniaturised using modern technologies allowing a fabrication on a large scale, for a mass production at low cost. Moreover, such devices could open the field of applications in a near future (environmental, biomedical, food industries, domotic and automotive applications etc.).

Technological needs for chemical, ionic and biological species detection are giving rise to continuous research and development in physico-chemistry and biology. The constant progress being made in the theoretical and technological aspects concerning studies and developments of chemical sensors, biosensors and biochips is presented in this book by different scientists and professors from different universities and constitutes an updating of the state of the art for chemical sensors, biosensors and biochips. This book places a large emphasis on interaction between chemical and biological species, in a gaseous or liquid state, and details mineral and biological materials acting as sensitive elements. The role of electrical, electrochemical, piezoelectric and optical transducers in detection mechanisms are presented through their developments and from a performance point-of-view. Micro-reactors, nanotechnologies and flexible substrates, are considered in relation to their role in neural networks. Contents 1. Chemical and Biological Recognition, Nicole Jaffrezic-Renault. 2. Adsorption Phenomena, René Lalauze. 3. Microcantilever Transduction, Isabelle Dufour. 4. Piezoelectric Transduction (QCM), Hubert Perrot. 5. Metal Oxide Gas Sensors, Christophe Pijolat. 6. Molecular Material-based Conductimetric Gas Sensors, Marcel Bouvet. 7. Responses and Electrical Properties of Gas Microsensors, Khalifa Aguir. 8. Gas Microsensor Technology, Philippe Menini. 9. Multisensors: Measurements and Behavior Models, Philippe Breuil. 10. Development of Microtechnologies for the Realization of Chemical, Biochemical and/or Biological Microsensors, Pierre Temple-Boyer. 11. Development of Micro-preconcentrators for the Detection of Gaseous Species at Trace Level, Jean-Paul Viricelle. 12. Microfluidics: Manipulation of Nanovolume Samples, Louis Renaud. 13. Electrochemical Biosensors, Chantal Gondran. 14. Fiber-optic Biosensors, Neso Sojic. 15. In Vivo Analyses with Electrochemical Microsensors, Stéphane Arbault. 16. Microbial Biosensors for Environmental Applications, Gérald Thouand and Marie José Durand. 17. Biofuel Cells, Serge Cosnier.

"This unique book is the only current publication that provides readers with a brief, yet concise, collection of the latest advances in chemical and biological agent detection and/or their surveillance. Nano and Microsensors for Chemical and Biological Terrorism Surveillance compiles and gives in-depth detail on several detection schemes so that the reader is provided with a general sense of these micro and nanoscale sensing systems and platforms." --Book Jacket.

Bringing together widely scattered information, Nanosensors: Physical, Chemical, and Biological explores sensor development in the nanotechnology age. This easy-to-read book presents a critical appraisal of the new opportunities in the area of sensors provided by nanotechnologies and nanotechnology-enabled advancements. After introducing nanosensor classification and fundamental terms, the book outlines the properties of important nanomaterials and nanotechnologies used in nanosensor fabrication. Subsequent chapters are organized according to nanosensor type: physical (mechanical and acoustical, thermal and radiation, optical, and magnetic); chemical (atomic and molecular energies); and biological. The final chapter summarizes the current state of the field and discusses future trends. A complete and authoritative guide to nanosensors, this book offers up-to-date information on the fabrication, properties, and operating mechanisms of these fast and reliable sensors. It addresses progress in the field, fundamental issues and challenges facing researchers, and prospects for future development.

Devoted primarily to the many applications of microsensors, this text covers thermal, radiation, mechanical, magnetic, chemical and biological microsensors. Information is also provided on basic processing, interfacing and bus systems, microsensor array and intelligent sensors.

This book, "Integrated Chemical Microsensor Systems in CMOS Technology", provides a comprehensive treatment of the highly interdisciplinary field of CMOS chemical microsensor systems. It is targeted at students, scientists and engineers who are interested in gaining an introduction to the field of chemical sensing since all the necessary fundamental knowledge is included. However, as it provides detailed information on all important issues related to the realization of chemical microsensors in CMOS technology, it also addresses experts well familiar with the field. After a brief introduction, the fundamentals of chemical sensing are presented. Fabrication and processing steps that are commonly used in the semiconductor industry are then detailed followed by a short description of the microfabrication techniques, and of the CMOS substrate and materials. Thereafter, a comprehensive overview of semiconductor-based and CMOS-based transducer structures for chemical sensors is given. CMOS-technology is then introduced as platform technology, which enables the integration of these microtransducers with the necessary driving and signal conditioning circuitry on the same chip. In a next section, the development of monolithic multisensor arrays and fully developed microsystems with on-chip sensor control and standard interfaces is described. A short section on packaging shows that techniques from the semiconductor industry can be applied to chemical microsensor packaging. The book concludes with a brief outlook on future developments, such as the realization of more complex integrated microsensor systems and methods to interface biological materials, such as cells, with CMOS microelectronics.

This book is planned to publish with an objective to provide a state-of-art reference book in the area of microsensors for engineers, scientists, applied physicists and post-graduate students. Also the aim of the book is the continuous and timely dissemination of new and innovative research and developments in microsensors. This reference book is a collection of 13 chapters characterized in 4 parts: magnetic sensors, chemical, optical microsensors and applications. This book provides an overview of resonant magnetic field microsensors based on MEMS, optical microsensors, the main design and fabrication problems of miniature sensors of physical, chemical and biochemical microsensors, chemical microsensors with ordered nanostructures, surface-enhanced Raman scattering microsensors based on hybrid nanoparticles, etc. Several interesting applications area are also discusses in the book like MEMS gyroscopes for consumer and industrial applications, microsensors for non invasive imaging in experimental biology, a heat flux microsensor for direct measurements in plasma surface interactions and so on.