Cingulate Neurobiology And Disease

One of the major neuroscience publications of the past few years, Cingulate Neurobiology and Disease presents the definitive review of the cingulate cortex, explaining its critical role in a host of diseases and illnesses.

New edition building on the success of previous one. Retains core aim of providing an accessible introduction to behavioral neuroanatomy.

Cingulate Cortex, Volume 166 summarizes research on the cingulate cortex, including its structure and function in health and how it is compromised in disease or trauma. Chapters discuss the cingulate organization by region and area, cover its function in consciousness, attention, social cognition and spatial orientation, review neurological disorders with cingulate involvement, including neurodegenerative disorders, movement disorders, Parkinson’s, ADHD, Cognitive impairment, Palsy, Tourette’s Syndrome, chronic pain, seizures, and more. Final sections discuss the relationship between the cingulate cortex, stress and psychiatric disorders. Coverage here includes PTSD, anxiety, depression, and evidence-based treatment for same. Identifies the structure and function of all areas and regions of the cingulate cortex Discusses its role in sensory-motor, cognitive and emotional processing Covers cingulate-mediated neurological and psychiatric disorders Supplies evidence-based treatment for cingulate mediated disorders

Uniting attachment-focused therapy and neurobiology to help distrustful and traumatized children revive a sense of trust and connection. How can therapists and caregivers help maltreated children recover what they were born with: the potential to experience the safety, comfort, and joy of having trustworthy, loving adults in their lives? This groundbreaking book explores, for the first time, how the attachment-focused family therapy model can respond to this question at a neural level. It is a rich, accessible investigation of the brain science of early childhood and developmental trauma. Each chapter offers clinicians new insights—and powerful new methods—to help neglected and insecurely attached children regain a sense of safety and security with caring adults. Throughout, vibrant clinical vignettes drawn from the authors' own experience illustrate how informed clinical processes can promote positive change. Authors Baylin and Hughes have collaborated for many years on the treatment of maltreated children and their caregivers. Both experienced psychologists, their shared project has bee the development of the science-based model of attachment-focused therapy in this book—a model that links clinical interventions to the crucial underlying processes of trust, mistrust, and trust building—helping children learn to trust caregivers and caregivers to be the "trust builders" these children need. The book begins by explaining the neurobiology of blocked trust, using the latest social neuroscience to show how the child's early development gets channeled into a core strategy of defensive living. Subsequent chapters address, among other valuable subjects, how new research on behavioral epigenetics has shown ways that highly stressful early life experiences affect brain development through patterns of gene expression, adapting the child's brain for mistrust rather than trust, and what it means for treatment approaches. Finally, readers will learn what goes on in the child's brain during attachment-focused therapy, honing in on the dyadic processes of adult-child interaction that seem to embody the core "mechanisms of change": elements of attachment-focused interventions that target the child's defensive brain, calm this system, and reopen the child's potential to learn from new experiences with caring adults, and that it is safe to depend upon them. If trust is to develop and care is to be restored, clinicians need to know what prevents the development of trust in the first place, particularly when a child is living in an environment of good care for a long period of time. What do abuse and neglect do to the development of children's brains that makes it so difficult for them to trust adults who are so different from those who hurt them? This book presents a brain-based understanding that professionals can apply to answering these questions and encouraging the development of healthy trust.

Encompassing the contributions of expert clinicians and researchers in the area of traumatic stress and dissociation, this volume is the first to integrate current neuroscience research regarding traumatic dissociation with several cutting-edge approaches to treatment, providing a comprehensive, neurobiologically based treatment approach. The text discusses current neuroscientific research regarding traumatic stress and dissociation that includes attachment, affective neuroscience, polyvagal theory, structural dissociation, and information processing theory, yielding a comprehensive model that guides treatment and clinical interventions for traumatic dissociation. It then integrates this model with stage-oriented treatment and current therapeutic interventions, including EMDR, somatic and body psychotherapy approaches, Ego State Therapy, and adjunctive pharmacological interventions. Readers are given hands-on practical guidance regarding clinical decision making, enabling them to make sound choices about interventions that will facilitate optimal treatment outcomes. Key Features: Provides a broad-based treatment approach to traumatic stress syndromes and dissociation Offers accessible current research in the basic neurosciences relevant to our understanding of attachment, traumatic stress, and dissociation Includes practical suggestions for integrating EMDR, somatic, and body psychotherapy approaches with Ego State Therapy and adjunctive pharmacological interventions Integrates concepts from the affective and cognitive neurosciences and the study of consciousness Presents a comprehensive neurobiological model that accounts for the therapeutic effects of both somatic therapies and EMDR, as well as adjunctive pharmacological interventions

Some well-known age-related neurological diseases include Parkinson's disease, Alzheimer's disease, deafness, and blindness. Even more common are the problems of aging which are not due to disease but to more subtle impairments in neurobiological systems, including impairments in vision, memory loss, muscle weakening, and loss of reproductive functions, changes in body weight, and sleeplessness. As the average age of our society increases, diseases of aging continue to become more common, and conditions associated with aging need more attention by doctors and researchers. In 1991, patients over the age of 65 saw their doctors an average of eight times per year. Research funding is provided by the Neuroscience and Neuropsychology of Aging (NNA) Program, which is run by the National Institute on Aging. This book offers a comprehensive overview of all topics related to functional impairments which are related to the aging brain and nervous system. It is organized according to four general functions: movement, senses, memory, and neuroendocrine regulation. Written by the leading researchers in the field, this comprehensive work addresses both impairments associated with diseases and not associated with diseases, making it easier to understand the mechanisms involved. Functional Neurobiology of Aging is an important reference for professionals and students involved in aging research, as well as physicians who need to recognize and understand age-related impairments. Organized by function, making it easy to find and understand the material Addresses impairments both associated with diseases and not associated with diseases Written by leading researchers in the field Most comprehensive source of information on the neurobiology of aging

A study that goes beyond the debate over functional specialization to describe the ways that emotion and cognition interact and are integrated in the brain. The idea that a specific brain circuit constitutes the emotional brain (and its corollary, that cognition resides elsewhere) shaped thinking about emotion and the brain for many years. Recent behavioral, neuropsychological, neuroanatomy, and neuroimaging research, however, suggests that emotion interacts with cognition in the brain. In this book, Luiz Pessoa moves beyond the debate over functional specialization, describing the many ways that emotion and cognition interact and are integrated in the brain. The amygdala is often viewed as the quintessential emotional region of the brain, but Pessoa reviews findings revealing that many of its functions contribute to attention and decision making, critical components of cognitive functions. He counters the idea of a subcortical pathway to the amygdala for affective visual stimuli with an alternate framework, the multiple waves model. Citing research on reward and motivation, Pessoa also proposes the dual competition model, which explains emotional and motivational processing in terms of their influence on competition processes at both perceptual and executive function levels. He considers the broader issue of structure-function mappings, and examines anatomical features of several regions often associated with emotional processing, highlighting their connectivity properties. As new theoretical frameworks of distributed processing evolve, Pessoa concludes, a truly dynamic network view of the brain will emerge, in which "emotion" and "cognition" may be used as labels in the context of certain behaviors, but will not map cleanly into compartmentalized pieces of the brain.