Clinical Approaches In Endodontic Regeneration

This richly illustrated book combines explanation of the scientific base underpinning vital pulp treatment with description of current and emerging trends in clinical practice. It guides the reader through modern views on pulp diagnostics, deep caries, and pulp exposure management, leading to an analysis of the biological aspects of regenerative techniques such as angiogenesis, neurogenesis, inflammation, and epigenetics. In the later chapters, practical considerations relating to bioengineering, biomaterial choice, revitalization, and stem cell-based procedures are discussed and their likely therapeutic impact considered. Aimed at dental students, postgraduates, and research-minded dental practitioners, this translational book summarizes state-of-the-art scientific knowledge on dentin–pulp interactions and regenerative endodontics, while highlighting the opportunities to incorporate recent developments into everyday practice. Readers will also find extensive discussion of potential future developments and research avenues relating to each aspect of this exciting and rapidly developing field.

This book provides evidence-based information in the field of regenerative dentistry discussing the most recent advances, current clinical applications, limitations and future directions. The coverage encompasses the regeneration of alveolar bone, the dentine-pulp complex, enamel, the periodontium and other tissues associated with the oral cavity. A full description is provided of regenerative approaches in dentistry including regenerative endodontics and tooth repair, regenerative periodontics, regenerative assisted orthodontics, regenerative approaches in oral medicine, and dental tissue derived stem cells and their potential applications. The book is written by an international team of leading experts. It will be beneficial for students, practitioners and researchers in the fields of endodontics, periodontics and implantology.

Regenerative endodontics is the generation and replacement of diseased, damaged or absent pulp. This issue of Dental Clinics of North America provides a clinical view of regenerative endodontics and its aims, methods and techniques.

As a first year mds student , thrown into the ocean of dentistry was a bit clueless about intricacies of the enormous array of regenerative endodontics being taught, not understanding why I needed to be so thorough with so many aspects of regeneration and other disciplines . It took me a year when I started studying its properties and behaviour. Probably the seed of this book was sown then. As CHARLES WILLIAM ELIOT observed “Books are the quietest and most constant friends; they are the most accessible and wisest counsellors. The chapters in this book have a flow were the story unfolds as one reads on in a clear, simple and stepwise manner. This textbook has tried to assemble the current knowledge of the subject along with traditional principles and concepts and presented to help in developing a better understanding of the subject. As we know conventional root canal therapy cleans and fills the pulp chamber with biologically inert material. Regenerative endodontics instead seeks to replace living tissue in the pulp chamber.

This issue of Dental Clinics of North America focuses on Endodontics, and is edited by Dr. Mo Kang. Articles will include: Endodontic Microbiology and Pathobiology: Current State of Knowledge; Conventional Endodontic Therapies: Innovation in Biomechanics; Endodontic Retreatments: Non-surgical and Surgical Approaches; Pain Management in Endodontics: Opportunity for New Therapeutics; Pulpal Management of Immature Teeth: Use of New Biomaterials for Conservative Therapies; Innovation in Bioactive Restorative Materials; Topic in Regenerative Endodontics; Biological Molecules for the Regeneration of the Pulp-dentin Complex; Cell Homing Approach in Endodontic Regeneration; Stem Cell Therapies for Oral and Systemic Diseases; Endodontic Treatment Outcomes, and more!

The authoritative reference that continues to present a systematic analysis of the scientific basis of endodontology The third edition of Essential Endodontology: Prevention and Treatment of Apical Periodontitis has been revised and updated to include the most recent developments in the field, maintaining its position as the major scientific treatise of apical periodontitis. Making an often-complex subject more digestible, the book explores the scientific basis of endodontology, adopting a systematic analysis of the available clinical and laboratory evidence. Promoting apical periodontitis as a disease entity, the comprehensive third edition focuses on its biology and clinical features, enabling the reader to have a better understanding of its diagnosis, prevention and treatment. In addition to thorough updates and full colour illustrations throughout, a new chapter on regenerative endodontics has been added to this edition. Written with a focus on the scientific basis of endodontology Includes a new chapter on regenerative endodontics Presents the most current information and major developments in this fast-moving field Provides helpful learning outcomes in each chapter Contains full colour illustrations, enriching the text Features contributions from a noted panel of international experts, including new contributors from across the globe Regarded as a vital companion to the pursuit of excellence in postgraduate and specialist education, Essential Endodontology is an indispensable and accessible resource for practicing endodontists, postgraduate students of endodontology and those seeking professional certification in endodontology.

Regenerative endodontics is the generation and replacement of diseased, damaged or absent pulp. This issue of Dental Clinics of North America provides a clinical view of regenerative endodontics and its aims, methods and techniques.

Sequential and reciprocal interactions between oral epithelial and cranial neural crest-derived mesenchymal cells give rise to the teeth and periodontium. Teeth are vital organs containing a rich number of blood vessels and nerve fibers within the dental pulp and periodontium. Teeth are composed by unique and specific collagenous (dentin, fibrillar cementum) and non-collagenous (enamel) highly mineralized extracellular matrices. Alveolar bone is another collagenous hard tissue that supports tooth stability and function through its close interaction with the periodontal ligament. Dental hard tissues are often damaged after infection or traumatic injuries that lead to the partial or complete destruction of the functional dental and supportive tissues. Well-established protocols are routinely used in dental clinics for the restoration or replacement of the damaged tooth and alveolar bone areas. Recent progress in the fields of cell biology, tissue engineering, and nanotechnology offers promising opportunities to repair damaged or missing dental tissues. Indeed, pulp and periodontal tissue regeneration is progressing rapidly with the application of stem cells, biodegradable scaffolds, and growth factors. Furthermore, methods that enable partial dental hard tissue repair and regeneration are being evaluated with variable degrees of success. However, these cell-based therapies are still incipient and many issues need to be addressed before any clinical application. The understanding of tooth and periodontal tissues formation would be beneficial for improving regenerative attempts in dental clinics. In the present e-book we have covered the various aspects dealing with dental and periodontal tissues physiology and regeneration in 6 chapters: 1. General principles on the use of stem cells for regenerating craniofacial and dental tissues 2. The roles of nerves, vessels and stem cell niches in tissue regeneration 3. Dental pulp regeneration and mechanisms of various odontoblast functions 4. Dental root and periodontal physiology, pathology and regeneration 5. Physiology and regeneration of the bone using various scaffolds and stem cell populations 6. Physiology, pathology and regeneration of enamel using dental epithelial stem cells