Clinical Endocrinology And Diagnostic Imaging

This monograph is based on the authors’ extensive experience in the areas of clinical endocrinology and diagnostic imaging, their clinical and research work and insight gained from teaching medical students and doctors in the Czech Republic and abroad. The chapters contain embryological and anatomical notes, clinical characteristics of individual endocrinopathies, laboratory and function tests, including reference values, indications and algorithms of imaging methods and principles of rational modern therapy of individual pathologies, including further clinical monitoring of patients. Texts also give practical advice regarding how to approach patients with endocrine gland diseases, point out some potential misinterpretations of examination results and are supplemented with numerous images of pathological states, which are almost exclusively sourced from the authors’ private archives. The chapter on diabetes mellitus centres on the complications of diagnosing diabetes and on the mutual relation between diabetes and other endocrinopathies. Focusing primarily on clinical practice, the work does not elaborate on pathophysiology, but covers only the most recent pertinent literature from the discipline. What makes this comprehensible publication exceptional is the fact that it not only presents the clinical view of the endocrinologist on the various covered subjects, but the reader is also given the opportunity to learn about current diagnostic trends using imaging methods. This interdisciplinary view offers the reader a comprehensive insight into the field and the necessary knowledge for their clinical practice. This monograph is intended for medical students, junior endocrinologists, diabetologists, radiologists and general practitioners interested in endocrinology, however, it can be useful also for doctors preparing for medical postgraduate certification in endocrinology and imaging methods as it undoubtedly provides valuable information.

Imaging in Endocrinology will provide endocrinologists and radiologists of all levels with an outstanding diagnostic imaging atlas to aid them in the diagnosis and management of all the major endocrine diseases they are likely to encounter. In full colour throughout, the 300 high-quality images consist of CT scans, MRI, NMR and histopathology slides, and are arranged by each specific endocrine condition, resulting in a visually outstanding and easily accessible tool that guides the user through exactly what to look out for and provides a practical and extremely useful aid in helping them formulate a diagnosis. Every major endocrine condition is covered in a specific section, including diseases of the thyroid, pituitary, reproductive and adrenal glands, the pancreas, bone metabolism problems, and the various forms of endocrine cancers. Each disease covered will offer a comparison of the normal findings so as to further assist in diagnosis. An accompanying website contains an online slide-atlas of all the figures in the book, to allow users to download all figures for use in presentations. Led by Paolo Pozzilli, an internationally-recognised expert in this field, the authors have assembled a wonderful collection of images that will be greatly valued by endocrinologists and radiologists alike, ensuring this is the perfect tool to consult when assessing patients with endocrine disease.

This issue of Endocrinology and Metabolism Clinics, guest edited by Drs. Richard Auchus, Adina Turcu, Alan D. Waxman, and Barry D. Pressman, is devoted to Biochemical and Imaging Diagnostics in Endocrinology. Articles in this issue include Mass spectrometry applicability in endocrine testing; Point-of-care endocrine testing; Thyroid, Bone; NET; Predictors of fertility; Thyroid ultrasound imaging and needle biopsy; Pituitary imaging; Adrenal imaging; Pancreatic imaging; Diagnosis and management of thyroid disorders; Neuroendocrine Tumors, and Parathyroid Imaging.

Revolutionary changes in medical imaging have enormously improved the ability to detect structural and functional organ alterations early. Imaging is becoming an essential tool - in association with hormonal assays - for the diagnosis and management of endocrine disorders. New contrast media and their application to ultrasounds, as well as the opportunity to merge images acquired by functional/metabolic and traditional techniques, allow characterization of key features of identified lesions. Some radiological techniques such as ultrasonography, CT, and MRI are now available in operating rooms, thus supporting a diagnostic and therapeutic approach to endocrine diseases. In this new book, distinguished experts have contributed concise and well-illustrated chapters to describe pathognomonic features of several benign and malignant diseases affecting endocrine glands. They review the main advantages and disadvantages of each diagnostic technique along with indications for selecting a method. As a special feature, online videos of dynamic diagnostic and therapeutic procedures are available. Imaging in Endocrine Disorders is a must read and valuable reference for all professionals dealing with endocrine disorders, including internists and general practitioners who must manage the essential diagnostic workup.

This book provides a comprehensive guide for selective venous sampling procedures and the role of interventional radiologists in the care and treatment of patients with endocrine disorders. Disorders of the endocrine system involve an imbalance in the natural homeostasis of the hormones produced by the glands in the body. There are a variety of endocrine conditions that are characterized by either hormonal hyposecretion or hypersecretion. Percutaneous selective venous sampling is the gold standard diagnostic tool for the medical and surgical management of patients with a variety of such disorders. Selective venous sampling is a minimally invasive interventional procedure that interventional radiologists perform to localize sites of abnormal hormone secretion. Computed tomography and magnetic resonance imaging are the most used diagnostic imaging modalities in patients with the suspected endocrine disorder; however, their specificity is not optimal, and identifying a culprit gland is difficult based on imaging findings alone. Therefore, the ultimate decision for management depends on the outcome of selective venous sampling. As these various venous samplings are increasingly performed worldwide, the collaboration between interventional radiology, endocrinology, surgical endocrinology, surgical oncology, neurosurgery, and gynecology teams is essential. With limited literature on the topic, this volume fills the gap with in-depth coverage of selective venous sampling alongside the pathophysiology, epidemiology, clinical diagnosis, as well as medical, surgical, and interventional management of endocrine disorders. The book is divided into five parts: Clinical, Laboratory, and Radiological Diagnosis of Endocrine Disorders; Selective Venous Sampling in Interventional Radiology; Medical Treatment of Endocrine Disorders; Surgical Treatment of Endocrine Disorders; Interventional Treatment of Endocrine Disorders. Throughout these parts, endocrine disorders that require venous sampling are covered in depth: primary aldosteronism, primary hyperparathyroidism, Cushing’s disease, hormone-secreting pancreatic adenomas, and androgen-secreting ovarian tumors. There is additionally an emerging role for interventional management in thyroid gland disorders, which is covered here. This is an ideal guide for interventional radiologists caring for patients with endocrine disorders, as well as endocrinologists, endocrine surgeons, surgical oncologists, otolaryngologists, neurosurgeons, gynecologists, and nephrologists.

Nuclear medicine is an important element of daily practice for the endocrinologist, both for diagnosis and for treatment. The continuous rapid development of nuclear medicine procedures has created the need for a concise, up-to-date practical guide that presents the essential information required by the endocrinologist. This book is designed to ensure ease of use in clinical practice and provides the most relevant information on nuclear medicine as applied to endocrine pathology. It is divided into three sections covering general aspects of nuclear medicine, the role of nuclear endocrinology in diagnosis, and the role of nuclear endocrinology in therapy. The endocrine glands are covered by organ and by pathology. Pertinent background information is provided, choice of radiopharmaceutical is explained, and the role of different image acquisition techniques is discussed. In addition, informative clinical cases are presented with the aid of high-quality images.

Endocrinology is a complex specialty that spans a wide range of diseases, disorders, and conditions. The field is now moving toward an increasingly personalized approach to patient management, with a greater focus on mechanisms of disease and biomarkers. Written by internationally renowned specialists, the second edition of Endocrinology in Clinical Practice provides a cutting-edge, problem-orientated approach to the management of clinical problems in endocrinology. Highlights of the new edition include: An overview of neuroendocrine disease Strides made by the identification of aryl hydrocarbon receptor–interacting protein mutations in patients with familial isolated pituitary adenomas The diverse roles of IGF-I Changes in diagnostic imaging and the increasing use of positron emission tomography The rapidly increasing incidence of neuroendocrine tumors and their management Hereditary primary hyperparathyroidism and multiple endocrine neoplasia Mechanistic and genomic advances related to disorders of calcium regulation and infertility The endocrinology of aging Protocols for pituitary function testing With complete updates to existing chapters, the second edition also presents new research data, diagnostic techniques, treatment options, and safety concerns related to existing therapies. This edition offers current guidance and scientifically focused information relevant to a range of clinical problems, making it an essential reference for practicing endocrinologists and specialist clinicians.

This issue of Endocrinology and Metabolism Clinics, guest edited by Dr. Michael Mingzhao Xing, is dedicated to Thyroid Cancer. Topics include, but are not limited to, Current Histological Classification of Thyroid Cancer, Molecular Pathogenesis and Mechanisms of Thyroid Cancer, Clinical Diagnostic Evaluation of Thyroid Nodules, Molecular Diagnostic Evaluation of Thyroid Nodules, Clinical Risk Stratification of Differentiated Thyroid Cancer, Molecular Risk Stratification of Differentiated Thyroid Cancer, Conventional Thyroidectomy in the Treatment of Primary Thyroid Cancer, Neck Dissection in the Surgical Treatment of Thyroid Cancer, Conventional Robotic Endoscopic Thyroidectomy for Thyroid Cancer, Transoral Endoscopic Thyroidectomy for Thyroid Cancer, Conventional Radioiodine Therapy for Differentiated Thyroid Cancer, Re-differentiation of Radioiodine-refractory Thyroid Cancer for Radioiodine Treatment, Management of Papillary Thyroid Microcarcinoma, Conservative Surveillance Management of Low-risk Papillary Thyroid Microcarcinoma, Thyroid-stimulating Hormone Suppression Therapy in Differentiated Thyroid Cancer, Diagnostic Imaging Testing in the Surveillance of Thyroid Cancer Recurrence, Novel Drug Treatments of Progressive Radioiodine-refractory Differentiated Thyroid Cancer, Management of Anaplastic Thyroid Cancer, and Management of Medullary Thyroid cancer.