Clinical Management Of Uncomplicated Skin And Skin Structure Infections

Diagnosis techniques, differential diagnosis, patient characteristics, and management issues specific to each condition (eg, cellulitis, impetigo, folliculitis, wound infections, abscesses, erysipelas, and acute paronychia are presented. Appropriate antimicrobial therapy (oral and topical), antimicrobial activity of the vaious agents, pathogens involved, and resistant organisms are reviewed in detail. Special patient populations, including diabetics, immunocompromised, and penicillin-allergic patients, are also discussed.

The authors examine diagnosis techniques, differential diagnosis, patient characteristics, and management issues specific to each condition, including cellulitis, impetigo, folliculitis, wound infections, abscesses, erysipelas, and acute paronychia. The book describes appropriate antimicrobial therapy (oral and topical), antimicrobial activity of the various agents, pathogens involved, and resistant organisms. Sections cover special patient populations, including diabetic, immunocompromised, and penicillin-allergic patients.

With collaboration of Consulting Editor Dr. Helen Boucher, Guest Editor Dr. Henry Chambers has assembled expert authors to provide current clinical reviews on the diagnosis and treatment of soft tissue and skin infections. Articles are specifically devoted to the following topics: Mimics of Skin and Soft Tissue Infections; Cellulitis; Staphylococcal Skin and Soft Tissue Infections; Necrotizing Fasciitis, Clostridial Skin and Soft Tissue Infections, and Streptococcal Toxic Shock Syndrome; Skin Infections from Bites; Skin and Soft Tissue Infections in Intravenous Drug Users; Gram-negative Skin and Soft Tissue Infections; Skin and Soft Tissue Infections in Diabetics; Skin and Soft Tissue Infections in Non-HIV Immunocompromised Hosts; Approach to the Patient with a Skin and Soft Tissue Infection; and Decolonization of Staphylococcus aureus. Readers will come away with the clinical information needed to improve outcomes in patients with soft tissue and skin infections.

This comprehensive account of the human herpesviruses provides an encyclopedic overview of their basic virology and clinical manifestations. This group of viruses includes human simplex type 1 and 2, Epstein–Barr virus, Kaposi's Sarcoma-associated herpesvirus, cytomegalovirus, HHV6A, 6B and 7, and varicella-zoster virus. The viral diseases and cancers they cause are significant and often recurrent. Their prevalence in the developed world accounts for a major burden of disease, and as a result there is a great deal of research into the pathophysiology of infection and immunobiology. Another important area covered within this volume concerns antiviral therapy and the development of vaccines. All these aspects are covered in depth, both scientifically and in terms of clinical guidelines for patient care. The text is illustrated generously throughout and is fully referenced to the latest research and developments.

The quinolones are making a significant contribution to patient care and have added a new dimension to antibacterial therapy. During the last decade, they became important agents for treating hospital-acquired infections. This volume covers their mechanisms of action, resistance mechanisms and epidemiology, pharmacokinetics, safety and clinical applications. Their effectiveness for respiratory, urinary, sexually transmitted, skin, soft tissue, bone and joint infections, infections of the eyes, ears, nose and throat, and less common infections such as mycobacterial, Brucella and others are reviewed. Also described is their use in pediatric, oncology and immunocompromised patients. The quinolone story continues to be intriguing with exciting future implications.This monograph is an important comprehensive review and update for researchers and clinicians in pharmacology, clinical medicine, molecular and cell biology, epidemiology and the pharmaceutical industry.

Based on careful analysis of burden of disease and the costs ofinterventions, this second edition of 'Disease Control Priorities in Developing Countries, 2nd edition' highlights achievable priorities; measures progresstoward providing efficient, equitable care; promotes cost-effectiveinterventions to targeted populations; and encourages integrated effortsto optimize health. Nearly 500 experts - scientists, epidemiologists, health economists,academicians, and public health practitioners - from around the worldcontributed to the data sources and methodologies, and identifiedchallenges and priorities, resulting in this integrated, comprehensivereference volume on the state of health in developing countries.

Kucers’ The Use of Antibiotics is the definitive, internationally-authored reference, providing everything that the infectious diseases specialist and prescriber needs to know about antimicrobials in this vast and rapidly developing field. The much-expanded Seventh Edition comprises 4800 pages in 3 volumes in order to cover all new and existing therapies, and emerging drugs not yet fully licensed. Concentrating on the treatment of infectious diseases, the content is divided into four sections - antibiotics, anti-fungal drugs, anti-parasitic drugs, and anti-viral drugs - and is highly structured for ease of reference. Each chapter is organized in a consistent format, covering susceptibility, formulations and dosing (adult and pediatric), pharmacokinetics and pharmacodynamics, toxicity, and drug distribution, with detailed discussion regarding clinical uses - a feature unique to this title. Compiled by an expanded team of internationally renowned and respected editors, with expert contributors representing Europe, Africa, Asia, Australia, South America, the US, and Canada, the Seventh Edition adopts a truly global approach. It remains invaluable for anyone using antimicrobial agents in their clinical practice and provides, in a systematic and concise manner, all the information required when prescribing an antimicrobial to treat infection.

This volume offers a comprehensive overview of basic and applied aspects of Staphylococcus aureus, which is one of the most important human pathogens. It includes sixteen chapters that address the microbiology and immunology of S. aureus, the pathology of its key manifestations, and the current standard of care. Further, it reviews cutting-edge advances in alternative therapeutic and prophylactic approaches to antibiotics. All chapters were written by respected experts in the field – presenting recent findings on a diverse range of aspects, they are nonetheless interlinked. As such, the book is a must-read for all researchers, clinicians and technicians engaged in basic or applied science work involving S. aureus.