Clinical Trials In Optic Nerve Disease Treatment

This book is a compendium of the worldwide ocular stem cell, gene therapy, and other studies treating Optic Nerve Disease that are registered with Clinicaltrials.gov. The study and the Clinical Trial number is provided in order to make it easier for the reader to obtain further information. The book contains an introduction to Optic Nerve Disease as well as a summary of common optic nerve conditions. Clinical Trials in Optic Nerve Disease Treatment is a valuable resource for ophthalmologists, optometrists, other physicians, and researchers.

This is the first practical reference book focusing only on common optic nerve disorders. The author discusses diagnosis, pathophysiology, management, and prognosis of complex optic nerve disorders. The book is organized by optic nerve diagnoses commonly encountered in a neuro-ophthalmologic practice. It is written in a clear, concise style for quick, easy reference in the clinic. Each chapter is formatted in a similar manner. Neurologists and ophthalmologists will find this book useful when they need a practical reference for incorporating optic nerve evaluation in their clinical practice.

Optic Nerve Disorders: Diagnosis and Management, Second Edition, is a thoroughly revised and updated reference, including new information on diagnostic techniques such as genetic testing for hereditary optic neuropathies, new data on toxic/drug-related optic neuropathies and recent data from clinical trial studies. Additional novel therapies, including stem cell therapies, the use of nanotechnology and gene therapies are featured highlights, as is spectral domain optical coherence tomography (OCT) for imaging of the optic nerve. The way in which OCT is used in differentiating optic nerve disorders from other retinal disorders and how OCT is used in monitoring the course of the disease, is also discussed. This practical reference focuses on common optic nerve disorders. It addresses diagnosis, pathophysiology, management and prognosis and is written in a clear, concise style for quick, easy reference in the clinic. With additional color photographs to better illustrate the material, the second edition will prove to be the go-to reference for ophthalmologists, neurologists and neurosurgeons working with optic nerve disorders.

This volume offers every clinical ophthalmologist valuable guidance in implementing the results of the latest multicenter clinical trials in practice. Chapters on all major disease entities review all pertinent trials, bring these trials into a real-world setting, and show how the results should influence day-to-day patient management. Coverage includes diseases in all ophthalmologic subspecialties—cornea/external disease, glaucoma, retina, pediatric ophthalmology, ocular oncology, neuro-ophthalmology, and oculoplastics. More than 170 illustrations, 92 in full color, complement the text. General ophthalmologists will have at their fingertips, in an easily digestible format, the current standard of patient care across the spectrum of ophthalmology.

This is a concise how-to of successfully treating previously deemed "untreatable" retinal and optic nerve conditions with stem cell therapies. Based on the results of 11 years of experience treating approximately 600 patients, this text will serve as a template for others to develop similar stem cell based treatments in their specialty. Author, Jeffrey N. Weiss, MD is specifically poised to offer dependable insight on stem cell surgery for both the retina and the optic nerve, having performed the first retinal stem cell surgery in 2010, with Institutional Review Board (IRB) approved studies that are registered with the National Institute of Health (NIH), and listed on ClinicalTrials.gov. Featuring all original work from Dr. Jeffrey Weiss's specialization in stem cell ophthalmology, this book is primarily written for ophthalmologists, but structured so that specialists across disciplines can take the model presented and create their own studies and clinical trials using stem cell therapies.

Now in a revised and updated Second Edition, this handy guide to eye care uses evidence from the latest clinical trials to deliver practical advice directly applicable to the challenges of daily ophthalmic practice. Helpful illustrations and tables support the text and improve outcomes.

Each chapter in this unique resource summarizes the important findings and recommendations of a major clinical trial. Readers will find the rationale for the study and a description of its primary and secondary outcomes. The patient population is described along with the different arms of treatment undertaken. Treatments are discussed, with tables that summarize how patients meeting various criteria should be treated.