Cochlear Mechanisms Structure Function And Models

Great advances have been made in understanding hearing in recent years. In particular, the mechanical function of the cochlea has become the focus of intense interest. This started in one direction, with the discovery of otoacoustic emissions in 1978, which required active mechanical amplification processes, as first postulated by Gold in 1948. Direct evidence for the role of this mechanism in sharpening-up the otherwise poor, basilar membrane tuning properties, was provided in 1982; and in 1983, motility was shown in outer hair cells. In parallel, an immense amount of work has been done on the electrophysiology of hair cells, following the first intracellular recordings in 1977. Over a longer time scale, models of basilar membrane motion have been developed and refined, and recently much effort has been put into incorporating active mechanisms and non-linear processes. It seemed an opportune time to bring together the leading workers in these various areas, to take stock of the whole field and to stimulate further progress. This book represents the proceedings of a NATO ARW on the Mechanics of Hearing held at the University of Keele, 3-8 July, 1988. The conception of the meeting owes much to earlier meetings held in Boston in 1985 (Peripheral Auditory Mechallisms, Eds. J.B. Allen, J.L.

Proceedings of a workshop on the physics and biophysics of hearing that brought together experimenters and modelers working on all aspects of audition. Topics covered include: cochlear mechanical measurements, cochlear models, mechanicals and biophysics of hair cells, efferent control, and ultrastructure.

Auditory Physiology and Perception documents the proceedings of the 9th International Symposium on Hearing held in Careens, France, 9-14 June 1991. The aim of the symposium was to promote exchanges between hearing scientists working with different approaches from cell biology to psychology. The volume is organized into 10 parts. Part I contains papers on the biology of inner ear cells. Part II presents studies on auditory periphery functioning. Part III examines frequency selectivity while Part IV contains papers that deal with the subject of pitch. The papers in Part V examine the coding of intensity. Parts VI and VII discuss temporal analyses and spectral shape analysis, respectively. Part VIII takes up spectro-temporal processing. Part IX covers binaural interactions and sound localization. The studies in Part X focus on pathologies, such as the relations between evoked otoacoustic emissions and pure tone audiometry and the effect of short duration acoustic trauma on activity of single neurons in the ventral cochlear nucleus. The final chapter of the text is a tribute to Professor Zwicker, a leading scientist in hearing, who passed away some months before the symposium.

The auditory system presents many features of a complex computational environment, as well as providing numerous opportunities for computational analysis. This volume represents an overview of computational approaches to understanding auditory system function. The chapters share the common perspective that complex information processing must be understood at multiple levels; that disciplines such as neurobiology, psychophysics, and computer science make vital contributions; and that the end product of computational analysis should be the development of formal models.

The function of vertebrate hearing is served by a surprising variety of sensory structures in the different groups of fish, amphibians, reptiles, birds, and mammals. This book discusses the origin, specialization, and functional properties of sensory hair cells, beginning with environmental constraints on acoustic systems and addressing in detail the evolutionary history behind modern structure and function in the vertebrate ear. Taking a comparative approach, chapters are devoted to each of the vertebrate groups, outlining the transition to land existence and the further parallel and independent adaptations of amniotic groups living in air. The volume explores in depth the specific properties of hair cells that allowed them to become sensitive to sound and capable of analyzing sounds into their respective frequency components. Evolution of the Vertebrate Auditory System is directed to a broad audience of biologists and clinicians, from the level of advanced undergraduate students to professionals interested in learning more about the evolution, structure, and function of the ear.

This book contains the proceedings of an international hearing-research conference held in Germany 2002. The conference brought together experts in genetics, molecular and cellular biology, physiology, engineering, physics, mathematics, audiology and medicine to synthesize and extend our understanding of how the cochlea works. Topics are discussed experimentally and theoretically at the molecular, cellular and whole-organ levels. Some of the topics are: mechanosensitivity of motor proteins; mechanochemical transduction by motor proteins; mechanoelectrical transduction in the stereocilia of hair cells; electromechanical transduction in the stereocilia, soma and synapses of hair cells; multidimensional vibration of the organ of Corti; and otoacoustic emissions. This book will be invaluable to researchers and students in auditory science.

A thesis about nonlinearity in the cochlea. Outer Hair Cells in the Organ of Corti amplify sound waves in a nonlinear way. For instance, they produce combination tones that do not exist in the original sound wave.

A message from a speaker to a listener has to travel a very long way, from an intention on the part of the former, via an acoustic signal, through the transducer stages of the peripheral auditory system. The present book is about the listener. It consists of 35 papers by researchers from a limited number of related fields between the auditory periphery and word recognition, who met in 1991.