Cognitive Enhancement In Schizophrenia And Related Disorders

A practical guide on how to assess and treat schizophrenia and related disorders using cognitive rehabilitation.

Disturbances of various domains of cognitive function have been shown to provide a major determinant of outcome for patients with psychiatric conditions. Cognitive impairment is present in an array of diseases, including schizophrenia (with its prodromal stage), mood disorder, autism spectrum disorder, obsessive-compulsive disorder, anxiety disorder, post-traumatic disorder, and eating disorder. In an effort to develop effective therapeutics for cognitive impairment, bridging of preclinical and clinical evidence has been attempted. This edited Book will provide a forum for researchers and clinicians interested in the phenomenology, underlying mechanisms, and treatment of cognitive impairment associated with psychiatric illnesses. Twenty-eight contributions from 8 countries in Europe, Middle East, Asia, North America, and South America represent studies dealing with genetic, molecular, imaging, physiological, psychological, and behavioral issues. Information in this Book will facilitate the development of therapeutics of greater clinical value.

Individuals with schizophrenia and related disorders experience significant functioning deficits in the community. The study of social cognition in schizophrenia has grown rapidly over the past decade, and a consensus has developed among researchers that dysfunction in social cognition may contribute to the severe interpersonal problems that are a hallmark of schizophrenia. This has generated hope that treatments which improve social cognition in this illness may enhance an individual's ability to live a socially engaged and rewarding life. Social Cognition in Schizophrenia: From Evidence to Treatment provides a firm grounding in the theory and research of normal social cognition, builds on this base to describe how social cognition appears to be dysfunctional in schizophrenia, and explains how this dysfunction might be ameliorated. Composed of contributed chapters written by the top experts in the field, the volume is divided into three parts to address each of these areas. Part I, Foundations of Human Social Cognition, explores normal social cognition in childhood development, adulthood, and across cultures, as well the brain-bases of social cognition and clinical social cognition research. Part II, Social Cognition in Schizophrenia: Descriptive and Experimental Research, discusses social cognition and functional outcome, emotion processing, Theory of Mind, paranoid ideation, social cognition in early psychosis, and the social cognitive neuroscience of schizophrenia. Part III, Social Cognition in Schizophrenia: Treatment Approaches, focuses on findings from current treatment outcome research as well as several leading social cognitive intervention approaches-Integrated Neurocognitive Therapy (INT), Cognitive Enhancement Therapy (CET), Metacognitive Training (MCT), and Social Cognition and Interaction Training (SCIT). This comprehensive, accessible volume will be invaluable to researchers studying social cognition and psychosocial treatment development in schizophrenia, clinicians working with this patient population, students in social and clinical psychology, nursing, social work and occupational therapy, and medical students.

Provides state-of-the-art information about cognition in schizophrenia with a wide ranging focus on measuring and treating cognitive deficits.

This volume covers the dramatic developments that have occurred in basic neuroscience and clinical research in cognitive neurology and dementia. It is based on the clinical approach to the patient, and provides essential knowledge that is fundamental to clinical practice.

Although the precise mechanisms and pathways of schizophrenia remain something of a mystery, there is little dispute that cognitive deficits present as some of the clearest and most debilitating symptoms of the disease. This book describes the characteristics of cognitive deficits in schizophrenia, functional implications, the course of impairments, the genetic and biological contributions and reviews management options, including neuropsychological, psychological and pharmacological techniques. Chapters are written by leading experts in the field, in an accessible and highly informative style, ensuring the content is clinically relevant. State-of-the-art information about new developments in the treatment of related features of the illness, such as disability, is provided. The wide ranging focus of this volume will appeal to clinicians and academic researchers working with patients impaired by severe mental illness.

Could CRT provide the first structured method of alleviating cognitive deficits associated with schizophrenia? Cognitive Remediation Therapy for Schizophrenia describes the background and development of this new psychological therapy and demonstrates how it provides the first structured help to overcome the thinking problems associated with schizophrenia. In three sections, the book covers the theoretical and empirical underpinning of cognitive remediation therapy and explores its application. Part I, 'The Development of Therapy', provides the historical context and theoretical background to the therapy and emphasizes the value of rehabilitating cognitive deficits. In Part II, 'Improving Cognitive Processes', the process and effects of changing cognition are examined. Finally, in Part III, 'The Process of Therapy', the authors provide a clinical guide to the delivery of cognitive remediation therapy and use case examples to support its efficacy. This book is the first to describe an individual cognitive remediation therapy programme based on a clear model of the relationship between thinking and behaviour. It will be of both academic and clinical value to all those health professionals and clinical academics who want not only to understand the relationships between thought and action but also to intervene to improve therapy.

Cognitive Enhancement: Pharmacologic, Environmental and Genetic Factors addresses the gap that exists in research on the topic, gathering multidisciplinary knowledge and tools that help the reader understand the basics of cognitive enhancement. It also provides assistance in designing procedures and pharmacological approaches to further the use of novel cognitive enhancers, a field that offers potential benefit to a variety of populations, including those with neurologic and psychiatric disorders, mild aging-related cognitive impairment, and those who want to improve intellectual performance. The text builds on our knowledge of the molecular/cellular basis of cognitive function, offering the technological developments that may soon enhance cognition. Separate sections cover enhancement drugs, environmental conditions, and genetic factors in terms of both human and animal studies, including both healthy/young and aging/diseased individuals. Provides a multidisciplinary knowledge, enabling a further understanding of cognitive enhancement Offers coverage of the pharmacologic, environmental, and genetic factors relevant to the topic Discusses cognitive enhancement from the perspective of both healthy and diseased or aging populations Topics are discussed in terms of both human and animal studies