Comprehensive Pharmacology

The Second Edition will continue this tradition of better preparing researchers in the basics of pharmacology. In addition, new human interest material including historical facts in pharmacology will be added. A new section on therapeutics will help readers identify with diseases and drug treatments. Over 30 new figures and tables More human interest information to provide readers with historical facts on pharmacology research New section on therapeutics to help identify diseaes and drug treatments New section on new biological concepts relevant to pharmacological research (i.e., systems biology) New study sections organized with ASPET and other international pharmacology organizations New coverage of pharmacokinetics and drug disposition

This resource provides simple explanations of the ways in which biological systems use basic biochemical mechanisms to produce fine chemical control of physiology, allowing for more informed predictions of drug effects in all systems and forming the basis of the drug-discovery process.

COMPREHENSIVE PHARMACOLOGY for Clinical Dentistry is a unique collection of therapeutic drugs relevant to Dentistry. Salient features include: • An “Introduction to pharmacology” that contains necessary information regarding General Pharmacology important for Dental students. • A “Therapeutic Drugs Classification” that contains Classes of Drugs, which are important for Dental Students and Dental Practitioners. Special feature of ‘Dental consideration’ has been added at the end of most chapters so, that Dental Students must know how to deal with a patient using that particular Drug, during dental procedures in his office. • And “Pharmacology in Dental Practice”, contains information regarding Drugs that are directly used by Dentist in his office.

Pharmacology in Drug Discovery and Development: Understanding Drug Response, Second Edition, is an introductory resource illustrating how pharmacology can be used to furnish the tools necessary to analyze different drug behavior and trace this behavior to its root cause or molecular mechanism of action. The concepts discussed in this book allow for the application of more predictive pharmacological procedures aimed at increasing therapeutic efficacy that will lead to more successful drug development. Chapters logically build upon one another to show how to characterize the pharmacology of any given molecule and allow for more informed predictions of drug effects in all biological systems. New chapters are dedicated to the interdisciplinary drug discovery environment in both industry and academia, and special techniques involved in new drug screening and lead optimization. This edition has been fully revised to address the latest advances and research related to real time kinetic assays, pluridimensional efficacy, signaling bias, irreversible and chemical antagonism, allosterically-induced bias, pharmacokinetics and safety, target and pathway validation, and much more. With numerous valuable chapter summaries, detailed references, practical examples and case studies throughout, Dr. Kenakin successfully navigates a highly complex subject, making it accessible for students, professors, and new researchers working in pharmacology and drug discovery. Includes example-based cases that illustrate how the pharmacological concepts discussed in this book lead to practical outcomes for further research Provides vignettes on those researchers and scientists who have contributed significantly to the fields of pharmacology and drug discovery throughout history Offers sample questions throughout the book and an appendix containing answers for self-testing and retention

This successful guide assists scientists trained in molecular biology and related fields who now need to know the basic theories, principles and practical applications of pharmacology. This latest edition continues the tradition of better preparing researchers in the basics of pharmacology. With expanded hands-on exercises and the addition of Pharmacokinetics coverage, new human interest material including historical facts in pharmacology and a new section on therapeutics that will help readers identify with diseases and drug treatments. The ideal book for researchers in drug discovery who have seen their role shift from "individual" to "team player" where that team includes chemists, biologists, and others with strong, but varied, science backgrounds who must now work together toward their common pharmacology goal. At GlaxoSmithKline, a pharmaceuticals world-leader, Terry Kenakin regularly teaches a course for their research scientists and has drawn on his experience to create a pharmacology primer. *New - Latest coverage of the chemistry of drugs including expanded coverage of the pharmacokinetic discussion of druglike properties -- Increases reader understanding of necessary ADME (Absorption, Distribution, Metabolism, and Excretion) properties and increases the rate of drug approval and acceptance. *Context - Unique discussions on various drug discovery teams and the role of the chemist on those teams -- Promotes the understanding of these expanding roles and responsibilities and how to maximize the effective contributions of each matrix team member. *Real-world learning - There are hands-on exercises, with extensive answers, utilizing real data on structure activity relationships; utilization of pharmacological principles to make general statements about how changes in structure lead to changes in drug activity. + hands on exercises with extensive answers on Pharmacokinetics -- Stengthens practical application and understanding of core concepts and principles. *Study sections are organized with ASPET (American Society for Pharmacology and Experimental Therapeutics)and other international organizations -- Ensures that learning follows professional industry standards.

A Pharmacology Primer: Techniques for More Effective and Strategic Drug Discovery, Fifth Edition features the latest ideas and research regarding the application of pharmacology to the process of drug discovery. Written by well-respected pharmacologist, Terry P. Kenakin, this primer is an indispensable resource for all those involved in drug discovery. This updated edition has been thoroughly revised to include material on quantifying drug efficacy through bias and cluster analysis, the impact of molecular dynamics and protein structural analysis, the real time kinetic analysis of drug effect, virtual screening for new drug chemical scaffolds, and much more. With full color illustrations and new examples throughout, this book remains a top reference for all industry and academic scientists that is also ideal for students directly involved in drug discovery or pharmacologic research. Highlights changes surrounding strategies for drug discovery, providing a comprehensive reference and featuring advances in the methods involved Includes multiple new sections, such as development and utilization of models in pharmacology, de-orphanization of new drug targets, predicting impact of disease on drug pharmacokinetics, and the impact of enzyme kinetics on drug-drug interactions Illustrates the application of rapid inexpensive assays to predict activity in the therapeutic setting, showing data outcomes and the limitations inherent in interpreting this data

Pharmacology doesn't have to be hard! Here's why: At Medical Creations, we are firm believers of the notion that the best way to learn a new topic is first to understand the fundamentals. Once you know the fundamentals, you will be able to understand the bigger picture. If you don't understand the bigger picture, forcing yourself to memorize any details becomes that much harder. Our Pharmacology book is meant to give you a good understanding of the topic before you can dive into the details with other, more extensive pharmacology books. The goal is to have you understand rather than memorize. It's a great alternative to the thicker and more expensive pharmacology books if you are studying for an exam and you just want a quick recap, or if you are just starting out and you want an overview. The purpose of this pharmacology book is to serve as a reference manual and a comprehensive study guide for medical, nursing, and paramedic students. For easy understanding of this complex subject, the book has been divided into multiple units based on each body system. The addition of multiple-choice questions will make it easier for you to remember the information from previous chapters. The key therapeutic drug classes for each major system have been outlined in separate chapters. Bullet points and tables make the content easy to understand. Pharmacology is a constantly evolving field, and new drugs are being developed every day. The main aim of this book is to familiarize the reader with the different categories of drugs. The most commonly prescribed drugs are described here, but the book is by no means exhaustive and does not cover all the drugs available today. For detailed descriptions of the latest drugs on the market, and less commonly prescribed drugs, the reader is referred to one of the more exhaustive textbooks of pharmacology. This book will help you: * ..Have a clear understanding of pharmacology * ..Learn about different groups of drugs, the pharmacokinetics, and the pharmacodynamics * ..Find pharmacology much more bearable Go to the top-right of the page and click "Add to Cart"