Comprehensive Toxicology Toxicology Testing And Evaluation

An explosive increase in the knowledge of the effects of chemical and physical agents on biological systems has led to an increased understanding of normal cellular functions and the consequences of their perturbations. The 14-volume Second Edition of Comprehensive Toxicology has been revised and updated to reflect new advances in toxicology research, including content by some of the leading researchers in the field. It remains the premier resource for toxicologists in academia, medicine, and corporations. Comprehensive Toxicology Second Edition provides a unique organ-systems structure that allows the user to explore the toxic effects of various substances on each human system, aiding in providing diagnoses and proving essential in situations where the toxic substance is unknown but its effects on a system are obvious. Comprehensive Toxicology Second Edition is the most complete and valuable toxicology work available to researchers today. Contents updated and revised to reflect developments in toxicology research Organized with a unique organ-system approach Features full color throughout Available electronically on sciencedirect.com, as well as in a limited-edition print version

Comprehensive Toxicology - the first comprehensive reference work in toxicology, is an in-depth, state-of-the-art review of toxicology of unrivalled quality. It is designed to encompass investigation from a molecular level to the intact organism. Presented in a 13-volume printed form.

This volume provides the reader with a comprehensive overview of the routine and special toxicologic assessments performed on pharmaceutical agents, chemicals, pesticides and consumer products. Toxicity testing procedures will be described emphasizing experimental design considerations (dose and species selection, toxicokinetic criteria) as well as regulatory guidelines and impacts of global harmonization efforts. The volume also provides insights into the risk assessment process in terms of evaluating and interpreting toxicity data relative to human safety.