Concepts And Challenges In The Biophysics Of Hearing With Cd Rom Proceedings Of The 10th International Workshop On The Mechanics Of Hearing

This book extends our understanding of the mechanics and biophysics of hearing by bringing together the latest research on the topic by experts in cell and molecular biology, physiology, physics, engineering and mathematics. It contains the proceedings of the 10th International Workshop on the Mechanics of Hearing that was held at Keele University in the United Kingdom at the end of July, 2008. Topics for discussion included theoretical and experimental research at the molecular, cellular and systems levels. Separate sections of the book deal with: the transmission of sound energy to and from the inner ear, and wave propagation within the inner ear; the enhancement of stimulus wave motion that occurs in the inner ear; new measurement techniques that will underpin future innovative studies; the micro-mechanics of the basilar and tectorial membranes and the organ of Corti; cochlear dynamics; sensory hair cells and electromechanical transduction; and sensory hair-bundles and mechano-electrical transduction. The book concludes with the transcript of an open discussion session between the participants of the workshop, highlighting areas of uncertainty and controversy in the field, and pointing the way to the solutions to be sought in future research. This book reviews and synthesizes current concepts and challenges in the biophysics of hearing, and will be an invaluable guide to researchers and students in all branches of auditory science.

Symposium held in 1999 near Sendai in Japan.

Proceedings of a workshop on the physics and biophysics of hearing that brought together experimenters and modelers working on all aspects of audition. Topics covered include: cochlear mechanical measurements, cochlear models, mechanicals and biophysics of hair cells, efferent control, and ultrastructure.

This book contains the proceedings of an international hearing-research conference held in Germany 2002. The conference brought together experts in genetics, molecular and cellular biology, physiology, engineering, physics, mathematics, audiology and medicine to synthesize and extend our understanding of how the cochlea works. Topics are discussed experimentally and theoretically at the molecular, cellular and whole-organ levels. Some of the topics are: mechanosensitivity of motor proteins; mechanochemical transduction by motor proteins; mechanoelectrical transduction in the stereocilia of hair cells; electromechanical transduction in the stereocilia, soma and synapses of hair cells; multidimensional vibration of the organ of Corti; and otoacoustic emissions. This book will be invaluable to researchers and students in auditory science. The proceedings have been selected for coverage in: • Index to Scientific & Technical Proceedings (ISTP CDROM version / ISI Proceedings) Contents:StereociliaHair CellsWhole-Organ MechanicsCochlear ModelsEmissionsDiscussion Session Readership: Hearing scientists (including medical persons in otolaryngology), biophysicists and molecular biologists, engineers interested in manufacturing silicon devices (MEMS), and persons interested in modelling biological systems. Keywords:Audition;Hearing;Cochlea;Biophysics;Hearing Impairment;Motor Molecules;Ion Channels;Interferometry;Otoacoustic EmissionsReviews:“In addition to the scientific papers, this book includes the comments and discussions raised for each manuscript at the time of its oral presentation, and most importantly, a final chapter with the edited transcript of the recording of a discussion session about outstanding topics of cochlear biophysics held by some of the most prominent researchers in the field. The first hand information provided by these transcripts is precisely what makes this book particularly interesting … The quality of this carefully edited book is excellent.”Audiology & Neuro-Otology

The workshop brought together experts in genetics, molecular and cellular biology, physiology, engineering, physics, mathematics, audiology and medicine to present current work and to review the critical issues of inner ear function. A special emphasis of the workshop was on analytical model based studies. Experimentalists and theoreticians thus shared their points of view. The topics ranged from consideration of the hearing organ as a system to the study and modeling of individual auditory cells including molecular aspects of function. Some of the topics in the book are: motor proteins in hair cells; mechanical and electrical aspects of transduction by motor proteins; function of proteins in stereocilia of hair cells; production of acoustic force by stereocilia, mechanical properties of hair cells and the organ of Corti; mechanical vibration of the organ of Corti; wave propagation in tissue and fluids of the inner ear; sound amplification in the cochlea; critical oscillations; cochlear nonlinearity, and mechanisms for the production of otoacoustic emissions. This book will be invaluable to researchers and students in auditory science.

The main aim of the symposium on the hearing system is to provide a forum in which data, ideas and models from both the physiological and psychoacoustical standpoints can be presented and discussed. Apart from those areas traditionally covered by such meetings, two areas with important recent advances have been included, viz, development and regeneration. The present volume will be of interest to all scientists working in the field of auditory research.

This proceedings volume contains papers presented during the meeting on Diversity in Auditory Mechanics by leading neurobiologists, biophysicists and mathematicians interested in auditory periphery.