Concepts In Vaccine Development
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Concepts in Vaccine Development
Author | : Stefan H. E. Kaufmann |
Publsiher | : Walter de Gruyter |
Total Pages | : 608 |
Release | : 2012-05-24 |
Genre | : Science |
ISBN | : 9783110906660 |
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Practical Aspects of Vaccine Development
Author | : Parag Kolhe,Satoshi Ohtake |
Publsiher | : Elsevier |
Total Pages | : 386 |
Release | : 2021-09-08 |
Genre | : Business & Economics |
ISBN | : 9780128143575 |
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Formulation, Development and Manufacturing of Vaccines: The Practical Aspects provides an industry perspective on vaccine product development and manufacture that covers their formulation development, manufacture and delivery/in-use considerations of vaccine production. With the increasing complexity of vaccine products in development, there is a need for a comprehensive review of the current state of the industry and its challenges. While formulation scientists working in biotherapeutic development may be familiar with proteins, vaccines present unique challenges, including the wide range of vaccine components that may comprise proteins, polysaccharides, protein-polysaccharide conjugates, adjuvants, etc. and the varying stability and behavior of solution- and suspension-based systems. This book is an essential resource for formulation scientists, researchers in vaccine development throughout medical and life sciences, and advanced students. Includes formulation considerations for various vaccine types, including proteins, polysaccharides, conjugates and live vaccines Considers process development for solution, suspension and lyophilized products Explores the future potential of vaccines, including multi-component vaccines and novel delivery mechanisms/devices
Vaccines for the 21st Century
Author | : Institute of Medicine,Division of Health Promotion and Disease Prevention,Committee to Study Priorities for Vaccine Development |
Publsiher | : National Academies Press |
Total Pages | : 472 |
Release | : 2001-02-21 |
Genre | : Medical |
ISBN | : 9780309174985 |
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Vaccines have made it possible to eradicate the scourge of smallpox, promise the same for polio, and have profoundly reduced the threat posed by other diseases such as whooping cough, measles, and meningitis. What is next? There are many pathogens, autoimmune diseases, and cancers that may be promising targets for vaccine research and development. This volume provides an analytic framework and quantitative model for evaluating disease conditions that can be applied by those setting priorities for vaccine development over the coming decades. The committee describes an approach for comparing potential new vaccines based on their impact on morbidity and mortality and on the costs of both health care and vaccine development. The book examines: Lessons to be learned from the polio experience. Scientific advances that set the stage for new vaccines. Factors that affect how vaccines are used in the population. Value judgments and ethical questions raised by comparison of health needs and benefits. The committee provides a way to compare different forms of illness and set vaccine priorities without assigning a monetary value to lives. Their recommendations will be important to anyone involved in science policy and public health planning: policymakers, regulators, health care providers, vaccine manufacturers, and researchers.
Vaccine Development and Manufacturing
Author | : Emily P. Wen,Ronald Ellis,Narahari S. Pujar |
Publsiher | : John Wiley & Sons |
Total Pages | : 452 |
Release | : 2014-11-17 |
Genre | : Technology & Engineering |
ISBN | : 9780470261941 |
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Vaccine Manufacturing and Production is an invaluable reference on how to produce a vaccine - from beginning to end - addressing all classes of vaccines from a processing, production, and regulatory viewpoint. It will provide comprehensive information on the various fields involved in the production of vaccines, from fermentation, purification, formulation, to regulatory filing and facility designs. In recent years, there have been tremendous advances in all aspects of vaccine manufacturing. Improved technology and growth media have been developed for the production of cell culture with high cell density or fermentation. Vaccine Manufacturing and Production will serve as a reference on all aspects of vaccine production by providing an in-depth description of the available technologies for making different types of vaccines and the current thinking in facility designs and supply issues. This book will provide insight to the issues scientists face when producing a vaccine, the steps that are involved, and will serve as a reference tool regarding state-of-the-art vaccine manufacturing technologies and facility set-up. Highlights include: Comprehensive coverage of vaccine production : from a process point of view- fermentation to purification to formulation developments; from a production point of view - from facility design to manufacturing; and from a regulatory point of view - requirements from government agencies Authors from different major pharmaceutical and biotechnology companies Describes the challenges and issues involved in vaccine production and manufacturing of the different classes of vaccines, an area not covered by other books currently on the market
Opportunities in Biotechnology for Future Army Applications
Author | : National Research Council,Division on Engineering and Physical Sciences,Board on Army Science and Technology,Committee on Opportunities in Biotechnology for Future Army Applications |
Publsiher | : National Academies Press |
Total Pages | : 118 |
Release | : 2001-07-11 |
Genre | : Science |
ISBN | : 9780309075558 |
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This report surveys opportunities for future Army applications in biotechnology, including sensors, electronics and computers, materials, logistics, and medical therapeutics, by matching commercial trends and developments with enduring Army requirements. Several biotechnology areas are identified as important for the Army to exploit, either by direct funding of research or by indirect influence of commercial sources, to achieve significant gains in combat effectiveness before 2025.
Vaccine Development From Concept to Clinic
Author | : A. Krishna Prasad |
Publsiher | : Royal Society of Chemistry |
Total Pages | : 323 |
Release | : 2022-11-09 |
Genre | : Medical |
ISBN | : 9781788018777 |
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Utilising successful case studies Vaccine Development will provide insight to the issues scientists face when producing a vaccine, the steps involved and will serve as an ideal reference tool regarding state-of-the-art vaccine development.
History of Vaccine Development
Author | : Stanley A. Plotkin |
Publsiher | : Springer Science & Business Media |
Total Pages | : 352 |
Release | : 2011-05-11 |
Genre | : Medical |
ISBN | : 9781441913395 |
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Vaccinology, the concept of a science ranging from the study of immunology to the development and distribution of vaccines, was a word invented by Jonas Salk. This book covers the history of the methodological progress in vaccine development and to the social and ethical issues raised by vaccination. Chapters include "Jenner and the Vaccination against Smallpox," "Viral Vaccines," and "Ethical and Social Aspects of vaccines." Contributing authors include pioneers in the field, such as Samuel L. Katz and Hilary Koprowski. This history of vaccines is relatively short and many of its protagonists are still alive. This book was written by some of the chief actors in the drama whose subject matter is the conquest of epidemic disease.
Vaccine Analysis Strategies Principles and Control
Author | : Brian K. Nunnally,Vincent E. Turula,Robert D. Sitrin |
Publsiher | : Springer |
Total Pages | : 669 |
Release | : 2014-11-27 |
Genre | : Medical |
ISBN | : 9783662450246 |
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This book is an indispensable tool for anyone involved in the research, development, or manufacture of new or existing vaccines. It describes a wide array of analytical and quality control technologies for the diverse vaccine modalities. Topics covered include the application of both classical and modern bio-analytical tools; procedures to assure safety and control of cross contamination; consistent biological transition of vaccines from the research laboratory to manufacturing scale; whole infectious attenuated organisms, such as live-attenuated and inactivated whole-cell bacterial vaccines and antiviral vaccines using attenuated or inactivated viruses; principles of viral inactivation and the application of these principles to vaccine development; recombinant DNA approaches to produce modern prophylactic vaccines; bacterial subunit, polysaccharide and glycoconjugate vaccines; combination vaccines that contain multiple antigens as well as regulatory requirements and the hurdles of licensure.