Constraining Chance

This text examines the representation and staging of chance in literature through the study of a specific case - the work of the 20th-century French writer Georges Perec (1936-82).

This book presents ideas and methods for directly optimizing the spatial layout of the landscape features in which an ecosystem functions. There is rich discussion of wildlife habitat issues as well as chapters on recreation, timber management, water runoff, and pest management.

A token of the world’s instability and of human powerlessness, chance is inevitably a crucial literary theme. It also presents formal problems: Must the artist struggle against chance in pursuit of a flawless work? Or does chance have a place in the artistic process or product? This book examines the representation and staging of chance in literature through the study of a specific case—the work of the twentieth-century French writer Georges Perec (1936–82). In Constraining Chance, James explores the ways in which Perec’s texts exploit the possibilities of chance, by both tapping into its creative potential and controlling its operation. These works, she demonstrates, strive to capture essential aspects of human life: its "considerable energy" (Perec’s phrase), its boundless possibilities, but also the constraints and limitations that bind it. A member of the Ouvroir de littérature potentielle (known as Oulipo), Perec adopted the group’s dictum that the literary work should be "anti-chance"—a product of fully conscious creative processes. James shows how Perec gave this notion a twist, using Oulipian precepts both to explore the role of chance in human existence and to redefine the possibilities of literary form. Thus the investigation of chance links Perec’s writing methods, which harness chance for creative purposes, to the thematic exploration of causality, chance, and fate in his writings. Constraining Chance has received early praise from scholars in the field. Warren F. Motte calls it "an erudite, engaging, intellectually intrepid reflection on the ways in which one of the most powerful authors of the twentieth century grappled with the notion of chance. [James] writes with both elegance and authority, inviting us to see Georges Perec's work through a new lens, one where chance may be viewed as a positive potential, fully enlisted in the service of ‘intentional’ literature."

Phenotypic Switching: Implications in Biology and Medicine provides a comprehensive examination of phenotypic switching across biological systems, including underlying mechanisms, evolutionary significance, and its role in biomedical science. Contributions from international leaders discuss conceptual and theoretical aspects of phenotypic plasticity, its influence over biological development, differentiation, biodiversity, and potential applications in cancer therapy, regenerative medicine and stem cell therapy, among other treatments. Chapters discuss fundamental mechanisms of phenotypic switching, including transition states, cell fate decisions, epigenetic factors, stochasticity, protein-based inheritance, specific areas of human development and disease relevance, phenotypic plasticity in melanoma, prostate cancer, breast cancer, non-genetic heterogeneity in cancer, hepatitis C, and more. This book is essential for active researchers, basic and translational scientists, clinicians, postgraduates and students in genetics, human genomics, pathology, bioinformatics, developmental biology, evolutionary biology and adaptive opportunities in yeast. Thoroughly addresses the conceptual, experimental and translational aspects that underlie phenotypic plasticity Emphasizes quantitative approaches, nonlinear dynamics, mechanistic insights and key methodologies to advance phenotypic plasticity studies Features a diverse range of chapter contributions from international leaders in the field

Presents an examination of American novels and nonfiction texts, published between 1947 and 2005, that looks at the concept of chance and how it was denied in the Soviet Union.

How the Biosphere Works: Fresh Views Discovered While Growing Peppers offers a simple and novel theoretical approach to understanding the history of the biosphere, including humanity’s place within it. It also helps to clarify what the possibilities and limitations are for future action. This is a subject of wide interest because today we are facing a great many environmental issues, many of which may appear unconnected. Yet all these issues are part of our biosphere. For making plans for the future and addressing our long-term survival and well-being, an integrated knowledge of our biosphere and its history is therefore indispensable. Key Features Documents what the biosphere is, and what our position as humans within it is today. Describes how the biosphere has become the way it is. Summarizes the novel simple theoretical model proposed in the book, and thus, how the biosphere functions. Predicts what the possibilities and limitations are for future human action Emphasizes how simple but careful observations can lead to far-reaching theoretical implications.

Examines Perec's impact on architecture, art, design, media, electronic communications, computing and the everydayWhat do Perec's descriptions of the minutiae of everyday life reveal about our use of information and communications technologies?What happens if we read Life: A Users Manual as a toolbox of ideas for games studies? What light does the concept of the ainfra-ordinary shed on social media? What insights does algorithmic writing generate for the digital humanities? What lessons can architects, artists, game-designers and writers draw from Perec's fascination with creative constraints? Through an examination of such questions, this collection takes Perec scholarship beyond its existing limits to offer new ways of rethinking our present.ContributorsTom Apperley, Monash University, Australia.Caroline Bassett, University of Sussex, UK. David Bellos, Princeton, USA.Justin Clemens, University of Melbourne, Australia.Ben Highmore, University of Sussex, UK.Alison James, University of Chicago, USA.Sandra Kaji-OGrady, University of Sydney, Australia. Christian Licoppe, TA(c)lA(c)com ParisTech, France.Anthony McCosker, Swinburne University of Technology, Melbourne, Australia. Mireille RibiA*re, independent scholar, translator and author.Darren Tofts, Swinburne University of Technology, Melbourne, Australia.Rowan Wilken, RMIT, Melbourne, Australia.Mark Wolff, Hartwick College in Oneonta, New York, USA.