Contact Problems For Soft Biological And Bioinspired Materials

This book contains contributions from leading researchers in biomechanics, nanomechanics, tribology, contact mechanics, materials science and applications on various experimental techniques including atomic force microscopy (AFM) for studying soft, biomimetic and biological materials and objects. Biologists, physicists, researchers applying methods of contact mechanics and researchers testing materials using indentation techniques along with many other applied scientists will find this book a useful addition to their libraries. Moreover, several reviews in this book are written as introductions to several important and rather sophisticated research areas such as depth-sensing indentation, studying of biological cells by AFM probes, mechanics of adhesive contact and contact between viscoelastic (hereditary elastic) solids. The book containing new theoretical models, results of experimental studies and numerical simulations, along with reviews of above mentioned areas of contact mechanics in application to biological systems, would be beneficial for researchers in many areas of biology, medicine, engineering, mechanics and biomimetics.

Taking a unique materials science approach, this text introduces students to the basic concepts and applications of materials and biomedical engineering and prepares them for the challenges of the new interdisciplinary field of biomaterials science. Split into three sections - Basic Biology Principles, Biological Materials, and Bioinspired Materials and Biomimetics - it presents biological materials along with the structural and functional classification of biopolymers, bioelastomers, foams, and ceramic composites. More traditional biomimetic designs such as Velcro are then discussed in conjunction with new developments that mimic the structure of biological materials at the molecular level, mixing nanoscale with biomolecular designs. Bioinspired design of materials and structures is also covered. Focused presentations of biomaterials are presented throughout the text in succinct boxes, emphasising biomedical applications, whilst the basic principles of biology are explained, so no prior knowledge is required. The topics are supported by approximately 500 illustrations, solved problems, and end-of-chapter exercises.

Global warming, pollution, food and water shortage, cyberspace insecurity, over-population, land erosion, and an overburdened health care system are major issues facing the human race and our planet. These challenges have presented a mandate to develop “natural” or “green” technologies using nature and the living system as a guide to rationally design processes, devices, and systems. This approach has given rise to a new paradigm, one in which innovation goes hand-in-hand with less waste, less pollution, and less invasiveness to life on earth. Bioinspiration has also led to the development of technologies that mimic the hierarchical complexity of biological systems, leading to novel highly efficient, more reliable multifunctional materials, devices, and systems that can perform multiple tasks at one time. This multi-volume handbook focuses on the application of biomimetics and bioinspiration in medicine and engineering to produce miniaturized multi-functional materials, devices, and systems to perform complex tasks. Our understanding of complex biological systems at different length scales has increased dramatically as our ability to observe nature has expanded from macro to molecular scale, leading to the rational biologically-driven design to find solution to technological problems in medicine and engineering.The following three-volume set covers the fields of bioinspired materials, electromechanical systems developed from concepts inspired by nature, and tissue models respectively.The first volume focuses on the rational design of nano- and micro-structured hierarchical materials inspired by the relevant characteristics in living systems, such as the self-cleaning ability of lotus leaves and cicadas' wings; the superior walking ability of water striders; the anti-fogging function of mosquitoes' eyes; the water-collecting ability of Namib Desert Beetles and spider silk; the high adhesivity of geckos' feet and rose petals; the high adhesivity of mussels in wet aquatic environments; the anisotropic wetting of butterflies' wings; the anti-reflection capabilities of cicadas' wings; the self-cleaning functionality of fish scales; shape anisotropy of intracellular particles; the dielectric properties of muscles; the light spectral characteristics of plant leaves; the regeneration and self-healing ability of earthworms; the self-repairing ability of lotus leaves; the broadband reflectivity of moths' eyes; the multivalent binding, self-assembly and responsiveness of cellular systems; the biomineral formation in bacteria, plants, invertebrates, and vertebrates; the multi-layer structure of skin; the organization of tissue fibers; DNA structures with metal-mediated artificial base pairs; and the anisotropic microstructure of jellyfish mesogloea. In this volume, sensor and microfluidic technologies combined with surface patterning are explored for the diagnosis and monitoring of diseases. The high throughput combinatorial testing of biomaterials in regenerative medicine is also covered.The second volume presents nature-oriented studies and developments in the field of electromechanical devices and systems. These include actuators and robots based on the movement of muscles, algal antenna and photoreception; the non-imaging light sensing system of sea stars; the optical system of insect ocellus; smart nanochannels and pumps in cell membranes; neuromuscular and sensory devices that mimic the architecture of peripheral nervous system; olfaction-based odor sensing; cilia-mimetic microfluidic systems; the infrared sensory system of pyrophilous insects; ecologically inspired multizone temperature control systems; cochlea and surface acoustic wave resonators; crickets' cercal system and flow sensing abilities; locusts' wings and flapping micro air vehicles; the visual motion sensing of flying insects; hearing aid devices based on the human cochlea; the geometric perception of tortoises and pigeons; the organic matter sensing capability of cats and dogs; and the silent flight of rats. The third volume features engineered models of biological tissues. These include engineered matrices to mimic cancer stem cell niches; in vitro models for bone regeneration; models of muscle tissue that enable the study of cardiac infarction and myopathy; 3D models for the differentiation of embryonic stem cells; bioreactors for in vitro cultivation of mammalian cells; human lung, liver and heart tissue models; topographically-defined cell culture models; ECM mimetic tissue printing; biomimetic constructs for regeneration of soft tissues; and engineered constructs for the regeneration of musculoskeletal and corneal tissue.This three-volume set is a must-have for anyone keen to understand the complexity of biological systems and how that complexity can be mimicked to engineer novel materials, devices and systems to solve pressing technological challenges of the twenty-first century.Key Features:The only handbook that covers all aspects of biomimetics and bioinspiration, including materials, mechanics, signaling and informaticsContains 248 colored figures

The special interest afforded biological and bioinspired materials and devices lies in the fact that many biological materials, as diverse as bone and teeth and spider silk, have highly refined and sophisticated platforms of structure that are well organized at hierarchical levels spanning nanoscale to microscale measures. There is absolutely strict and precise control of materials synthesis exerted by these natural systems, and vigorous study and advancement in the fields of biomineralization, molecular biology, and DNA technology, for instance, have brought increasing understanding of such control in ever expanding fashion. This knowledge has been quickly transferred into the design and development of synthetic materials that mimic their biological counterparts. In this context, an explosion in research in the past few years has centered on the identification and synthesis of 1) unique ceramics or composites for biomaterials, magnetic and optical use, 2) self-assembled biopolymeric systems for biomaterials and biosensor application, and 3) colloidal and amphiphilic systems for relevance in biomedicine, nanotechnology, and biosensor fabrication. Therefore, new nanocrystalline composites, nanofibers, biosteel fibers, novel biosensors, distinctive drug-delivery systems, exceptional tissue engineering scaffolds, exclusive molecular imprinting matrices, and innovative photonic crystals are suddenly available. Given this backdrop, the papers in this volume involve biology, medicine, engineering, physics, chemistry, and materials science. Topics include biomineralization and the structure and mechanical, magnetic, and optical properties of biominerals; implant materials for dental, maxillofacial, orthopaedic, urological, and ophthalmic applications; tissue adhesives and cements; material degradation and implant failure; organic modification of surfaces and their biocompatibility; tissue engineering with cells and scaffolding to generate extracellular matrices for tissue regeneration; emerging technologies in tissue engineering, including application of stem cells and gene therapy; in situ and ex situ characterization techniques and imaging of biomaterials; pharmaceutical crystallization and materials for drug and gene delivery; supramolecular and biological self assembly; and structure and dynamics of organic/inorganic interfaces.

Global warming, pollution, food shortage, security, and health care are major issues facing us and our planet. These global challenges have inspired scientists and engineers to design materials, processes, and enabling tools that mimic nature and are less intrusive. The aim of the Handbook of Biomimetics and Bioinspiration is to serve as a reference on synthesis, modification, assembly, packaging, transportation, targeting, and recognition at their destination, conservation of information and response to foreign invadors, the creation of a dynamic living system from these assemblies, and the use of the principles governing biological systems for creating novel biomimetic systems. Presented in a set of three volumes, this handbook covers biomimetics and bioinspiration within the scope of materials, mechanics, dynamics, transport, chemical reactions, control, recognition, and informatics.

Takes a materials science approach, correlating structure-property relationships with function across a broad range of biological materials.

Human cortical bone as a structural material : Hierarchical design and biological degradation / Robert Ritchie and Elizabeth A. Zimmermann -- Bio-inspiration from nacre / Nima Rahbar and Sina Askarinejad -- Bio-inspiration from bamboo / Ting Tan and Wole Soboyejo.

Nature has provided opportunities for scientists to observe patterns in biomaterials which can be imitated when designing construction materials. Materials designed with natural elements can be robust and environment friendly at the same time. Advances in our understanding of biology and materials science coupled with the extensive observation of nature have stimulated the search for better accommodation/compression of materials and the higher organization/reduction of mechanical stress in man-made structures. Bio-Inspired Materials is a collection of topics that explore frontiers in 3 sections of bio-inspired design: (i) bionics design, (ii) bio-inspired construction, and (iii) bio-materials. Chapters in each section address the most recent advances in our knowledge about the desired and expected relationship between humans and nature and its use in bio-inspired buildings. Readers will also be introduced to new concepts relevant to bionics, biomimicry, and biomimetics. Section (i) presents research concepts based on information gained from the direct observation of nature and its applications for human living. Section (ii) is devoted to ‘artificial construction’ of the Earth. This section addresses issues on geopolymers, materials that resemble the structure of soils and natural rocks; procedures that reduce damage caused by earthquakes in natural construction, the development of products from vegetable resins and construction principles using bamboo. The last section takes a look into the future towards the improvement of human living conditions. Bio-Inspired Materials offers readers - having a background in architecture, civil engineering and systems biology - a new perspective about sustainable building which is a key part of addressing the environmental concerns of current times.