Current Topics In Vector Research

Current Topics in Vector Research is based on the premise that to un derstand the whole, one must first understand the component parts and how they interact. Here in Volume 4, as well as in future volumes, vector, pathogen, and host will be treated both individually and as integral parts of multifaceted transmission systems. It is our intention to present up-to date, coherent syntheses of the latest findings in vector research, suggest promising frontiers for future research, and call attention to possible prac tical applications of our present understandings of pathogen-vector-host interactions. To realize our goals, we invite world-renowned, veteran sci entists as well as neophytes to report on their individual areas of expertise. Where appropriate, authors are encouraged to draw conclusions and pro pose hypotheses that stimulate additional thinking and research or oth erwise further our understanding of vector transmission cycles and how such cycles might be interrupted. It is our hope that readers will agree that we are serving these objectives and creating a milieu for specialists and generalists in vector research to maintain rapport and understanding.

Vector transmission of pathogens affecting human, animal, and plant health continues to plague mankind both in industrialized and Third World coun tries. The diseases caused by these pathogens cost billions of dollars an nually in medical expenses and lost productivity. Some cause widespread of food-and fiber-producing plants and animals, whereas others destruction present direct and immediate threats to human life and further development in Third World countries. During the past 15 years or so, we have witnessed an explosive increase in interest in how vectors acquire, carry, and subsequently inoculate dis ease agents to human, animal, and plant hosts. This interest transcends the boundaries of anyone discipline and involves researchers from such varied fields as human and veterinary medicine, entomology, plant pa thology, virology, physiology, microbiology, parasitology, biochemistry, molecular biology, genetic engineering, ultrastructure, biophysics, bio systematics, biogeography, ecology, behavioral sciences, and others. Ac companying and perhaps generating this renewed interest is the realization that fundamental knowledge of pathogen-vector-host interrelationships is a first and necessary step in our quest for efficient, safe methods of disease control.

Vector transmission of pathogens affecting human, animal, and plant health continues to plague mankind both in industrialized and Third World coun tries. The diseases caused by these pathogens cost billions of dollars an nually in medical expenses and lost productivity. Some cause widespread of food-and fiber-producing plants and animals, whereas others destruction present direct and immediate threats to human life and further development in Third World countries. During the past 15 years or so, we have witnessed an explosive increase in interest in how vectors acquire, carry, and subsequently inoculate dis ease agents to human, animal, and plant hosts. This interest transcends the boundaries of anyone discipline and involves researchers from such varied fields as human and veterinary medicine, entomology, plant pa thology, virology, physiology, microbiology, parasitology, biochemistry, molecular biology, genetic engineering, ultrastructure, biophysics, bio systematics, biogeography, ecology, behavioral sciences, and others. Ac companying and perhaps generating this renewed interest is the realization that fundamental knowledge of pathogen-vector-host interrelationships is a first and necessary step in our quest for efficient, safe methods of disease control.

This 6th volume of the ECVD series reflects on the progress of GVCR. The introduction and concluding chapters of the book have been written in collaboration with WHO.

Entomology, plant pathology and virology are a few of the disciplines covered by this well-reviewed series. It also covers the spectrum of vectors from mosquitos and leafhoppers to nematodes, and pathogens from viruses to mycoplasmas to protozoa. Articles deal with the emerging science of vector ecology, and consider both biotic and abiotic environmental influences on disease transmission. As a form to present current thinking in this field, the series is an important resource for researchers and students involved in understanding and overcoming the many vector-borne diseases of plants, animals, and humans.

Pathogens transmitted among humans, animals, or plants by insects and arthropod vectors have been responsible for significant morbidity and mortality throughout recorded history. Such vector-borne diseases â€" including malaria, dengue, yellow fever, and plague â€" together accounted for more human disease and death in the 17th through early 20th centuries than all other causes combined. Over the past three decades, previously controlled vector-borne diseases have resurged or reemerged in new geographic locations, and several newly identified pathogens and vectors have triggered disease outbreaks in plants and animals, including humans. Domestic and international capabilities to detect, identify, and effectively respond to vector-borne diseases are limited. Few vaccines have been developed against vector-borne pathogens. At the same time, drug resistance has developed in vector-borne pathogens while their vectors are increasingly resistant to insecticide controls. Furthermore, the ranks of scientists trained to conduct research in key fields including medical entomology, vector ecology, and tropical medicine have dwindled, threatening prospects for addressing vector-borne diseases now and in the future. In June 2007, as these circumstances became alarmingly apparent, the Forum on Microbial Threats hosted a workshop to explore the dynamic relationships among host, pathogen(s), vector(s), and ecosystems that characterize vector-borne diseases. Revisiting this topic in September 2014, the Forum organized a workshop to examine trends and patterns in the incidence and prevalence of vector-borne diseases in an increasingly interconnected and ecologically disturbed world, as well as recent developments to meet these dynamic threats. Participants examined the emergence and global movement of vector-borne diseases, research priorities for understanding their biology and ecology, and global preparedness for and progress toward their prevention, control, and mitigation. This report summarizes the presentations and discussions from the workshop.