Data Management Of Protein Interaction Networks
Download Data Management Of Protein Interaction Networks full books in PDF, epub, and Kindle. Read online free Data Management Of Protein Interaction Networks ebook anywhere anytime directly on your device. Fast Download speed and no annoying ads. We cannot guarantee that every ebooks is available!
Data Management of Protein Interaction Networks
Author | : Mario Cannataro,Pietro H. Guzzi |
Publsiher | : John Wiley & Sons |
Total Pages | : 145 |
Release | : 2012-02-03 |
Genre | : Computers |
ISBN | : 9781118103739 |
Download Data Management of Protein Interaction Networks Book in PDF, Epub and Kindle
Current PPI databases do not offer sophisticated querying interfaces and especially do not integrate existing information about proteins. Current algorithms for PIN analysis use only topological information, while emerging approaches attempt to exploit the biological knowledge related to proteins and kinds of interaction, e.g. protein function, localization, structure, described in Gene Ontology or PDB. The book discusses technologies, standards and databases for, respectively, generating, representing and storing PPI data. It also describes main algorithms and tools for the analysis, comparison and knowledge extraction from PINs. Moreover, some case studies and applications of PINs are also discussed.
Biological Data Mining in Protein Interaction Networks
Author | : Li, Xiao-Li,Ng, See-Kiong |
Publsiher | : IGI Global |
Total Pages | : 450 |
Release | : 2009-05-31 |
Genre | : Technology & Engineering |
ISBN | : 9781605663999 |
Download Biological Data Mining in Protein Interaction Networks Book in PDF, Epub and Kindle
"The goal of this book is to disseminate research results and best practices from cross-disciplinary researchers and practitioners interested in, and working on bioinformatics, data mining, and proteomics"--Provided by publisher.
Protein Interaction Networks
Author | : Aidong Zhang |
Publsiher | : Cambridge University Press |
Total Pages | : 283 |
Release | : 2009-04-06 |
Genre | : Computers |
ISBN | : 9781139479035 |
Download Protein Interaction Networks Book in PDF, Epub and Kindle
The analysis of protein-protein interactions is fundamental to the understanding of cellular organization, processes, and functions. Proteins seldom act as single isolated species; rather, proteins involved in the same cellular processes often interact with each other. Functions of uncharacterized proteins can be predicted through comparison with the interactions of similar known proteins. Recent large-scale investigations of protein-protein interactions using such techniques as two-hybrid systems, mass spectrometry, and protein microarrays have enriched the available protein interaction data and facilitated the construction of integrated protein-protein interaction networks. The resulting large volume of protein-protein interaction data has posed a challenge to experimental investigation. This book provides a comprehensive understanding of the computational methods available for the analysis of protein-protein interaction networks. It offers an in-depth survey of a range of approaches, including statistical, topological, data-mining, and ontology-based methods. The author discusses the fundamental principles underlying each of these approaches and their respective benefits and drawbacks, and she offers suggestions for future research.
Protein Protein Interaction Networks
Author | : Stefan Canzar,Francisca Rojas Ringeling |
Publsiher | : Humana |
Total Pages | : 0 |
Release | : 2019-10-04 |
Genre | : Science |
ISBN | : 1493998722 |
Download Protein Protein Interaction Networks Book in PDF, Epub and Kindle
This volume explores techniques that study interactions between proteins in different species, and combines them with context-specific data, analysis of omics datasets, and assembles individual interactions into higher-order semantic units, i.e., protein complexes and functional modules. The chapters in this book cover computational methods that solve diverse tasks such as the prediction of functional protein-protein interactions; the alignment-based comparison of interaction networks by SANA; using the RaptorX-ComplexContact webserver to predict inter-protein residue-residue contacts; the docking of alternative confirmations of proteins participating in binary interactions and the visually-guided selection of a docking model using COZOID; the detection of novel functional units by KeyPathwayMiner and how PathClass can use such de novo pathways to classify breast cancer subtypes. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary hardware- and software, step-by-step, readily reproducible computational protocols, and tips on troubleshooting and avoiding known pitfalls. Cutting-edge and comprehensive, Protein-Protein Interaction Networks: Methods and Protocols is a valuable resource for both novice and expert researchers who are interested in learning more about this evolving field.
Scientific Data Management
Author | : Arie Shoshani,Doron Rotem |
Publsiher | : CRC Press |
Total Pages | : 592 |
Release | : 2009-12-16 |
Genre | : Computers |
ISBN | : 9781420069815 |
Download Scientific Data Management Book in PDF, Epub and Kindle
Dealing with the volume, complexity, and diversity of data currently being generated by scientific experiments and simulations often causes scientists to waste productive time. Scientific Data Management: Challenges, Technology, and Deployment describes cutting-edge technologies and solutions for managing and analyzing vast amounts of data, helping
Heterogeneous Data Management Polystores and Analytics for Healthcare
Author | : Vijay Gadepally,Timothy Mattson,Michael Stonebraker,Tim Kraska,Fusheng Wang,Gang Luo,Jun Kong,Alevtina Dubovitskaya |
Publsiher | : Springer Nature |
Total Pages | : 235 |
Release | : 2021-03-03 |
Genre | : Computers |
ISBN | : 9783030710552 |
Download Heterogeneous Data Management Polystores and Analytics for Healthcare Book in PDF, Epub and Kindle
This book constitutes revised selected papers from two VLDB workshops: The International Workshop on Polystore Systems for Heterogeneous Data in Multiple Databases with Privacy and Security Assurances, Poly 2020, and the 6th International Workshop on Data Management and Analytics for Medicine and Healthcare, DMAH 2020, which were held virtually on August 31 and September 4, 2020. For Poly 2020, 4 full and 3 short papers were accepted from 10 submissions; and for DMAH 2020, 7 full and 2 short papers were accepted from a total of 15 submissions. The papers were organized in topical sections as follows: Privacy, Security and/or Policy Issues for Heterogenous Data; COVID-19 Data Analytics and Visualization; Deep Learning based Biomedical Data Analytics; NLP based Learning from Unstructured Data; Biomedical Data Modelling and Prediction.
Scientific and Statistical Database Management
Author | : Michael Gertz,Bertram Ludäscher |
Publsiher | : Springer |
Total Pages | : 660 |
Release | : 2010-06-27 |
Genre | : Computers |
ISBN | : 9783642138188 |
Download Scientific and Statistical Database Management Book in PDF, Epub and Kindle
This book constitutes the proceedings of the 22nd International Conference on Scientific and Statistical Database Management, SSDBM 2010, held in Heidelberg, Germany in June/July 2010. The 30 long and 11 short papers presented were carefully reviewed and selected from 94 submissions. The topics covered are query processing; scientific data management and analysis; data mining; indexes and data representation; scientific workflow and provenance; and data stream processing.
Protein Interaction Networks in Health and Disease
Author | : Spyros Petrakis,Miguel A. Andrade-Navarro |
Publsiher | : Frontiers Media SA |
Total Pages | : 91 |
Release | : 2016-10-19 |
Genre | : Genetics |
ISBN | : 9782889199822 |
Download Protein Interaction Networks in Health and Disease Book in PDF, Epub and Kindle
The identification and mapping of protein-protein interactions (PPIs) is a major goal in systems biology. Experimental data are currently produced in large scale using a variety of high-throughput assays in yeast or mammalian systems. Analysis of these data using computational tools leads to the construction of large protein interaction networks, which help researchers identify novel protein functions. However, our current view of protein interaction networks is still limited and there is an active field of research trying to further develop this concept to include important processes: the topology of interactions and their changes in real time, the effects of competition for binding to the same protein region, PPI variation due to alternative splicing or post-translational modifications, etc. In particular, a clinically relevant topic for development of the concept of protein interactions networks is the consideration of mutant isoforms, which may be responsible for a pathological condition. Mutations in proteins may result in loss of normal interactions and appearance of novel abnormal interactions that may affect a protein’s function and biological cycle. This Research Topic presents novel findings and recent achievements in the field of protein interaction networks with a focus on disease. Authors describe methods for the identification and quantification of PPIs, the annotation and analysis of networks, considering PPIs and protein complexes formed by mutant proteins associated with pathological conditions or genetic diseases.